Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephen M. Ostrowski"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3541 (2023)
One effort to combat the rising incidence of malignant melanoma is focused on early detection by the clinical and dermoscopic screening of melanocytic nevi. However, the interaction between nevi, which are congenital or acquired benign melanocytic pr
Externí odkaz:
https://doaj.org/article/9f52035068934339924c898fba00b06e
Autor:
Stephen M. Ostrowski, David E. Fisher
Publikováno v:
Hematology/Oncology Clinics of North America. 35:29-56
Melanoma skin cancer is derived from skin melanocytes and has a high risk of metastatic spread. The era of molecular genetics and next-generation sequencing has uncovered the role of oncogenic BRAFV600E mutations in many melanomas, validated the role
Publikováno v:
Pediatric Dermatology. 38:149-151
Pyogenic granulomas are benign vascular proliferations of the skin and mucous membranes that tend to bleed easily. They typically require procedural treatments that can be difficult for patients with intellectual disabilities or behavioral concerns t
Autor:
David E. Fisher, Stephen M. Ostrowski
Publikováno v:
Journal of Investigative Dermatology. 141:250-252
Resistance to targeted therapy and immunotherapy remains a major obstacle in improving care for patients with advanced melanoma. MicroRNAs play important roles in regulating gene networks involved in disease progression and resistance to therapy in c
Autor:
Masahiro Shuda, Anna Guastafierro, Xuehui Geng, Yoko Shuda, Stephen M Ostrowski, Stefan Lukianov, Frank J Jenkins, Kord Honda, Stephen M Maricich, Patrick S Moore, Yuan Chang
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142329 (2015)
Merkel cell polyomavirus (MCV) causes the majority of human Merkel cell carcinomas (MCC) and encodes a small T (sT) antigen that transforms immortalized rodent fibroblasts in vitro. To develop a mouse model for MCV sT-induced carcinogenesis, we gener
Externí odkaz:
https://doaj.org/article/ee230b55f68646b08018e65853fa7d10
Publikováno v:
Journal of Investigative Dermatology. 141:S120
Autor:
Boris C. Bastian, Ashley Feneran, Beth S. Ruben, Kord Honda, Jeremy S. Bordeaux, Stephen M. Ostrowski, Madhulika Eluri
Publikováno v:
JAAD case reports, vol 3, iss 2
Eluri, M; Feneran, A; Bordeaux, JS; Ruben, B; Ostrowski, S; Bastian, BC; et al.(2017). Multiple Merkel cell carcinomas: Late metastasis or multiple primary tumors? A molecular study.. JAAD case reports, 3(2), 131-134. doi: 10.1016/j.jdcr.2017.01.011. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/8ph63232
JAAD Case Reports, Vol 3, Iss 2, Pp 131-134 (2017)
JAAD Case Reports
Eluri, M; Feneran, A; Bordeaux, JS; Ruben, B; Ostrowski, S; Bastian, BC; et al.(2017). Multiple Merkel cell carcinomas: Late metastasis or multiple primary tumors? A molecular study.. JAAD case reports, 3(2), 131-134. doi: 10.1016/j.jdcr.2017.01.011. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/8ph63232
JAAD Case Reports, Vol 3, Iss 2, Pp 131-134 (2017)
JAAD Case Reports
In the United States, the incidence and mortality rates for Merkel cell carcinoma (MCC) have more than tripled in the last 2 decades.1 The main risk factors involved in MCC pathogenesis include ultraviolet light exposure, immunosuppression, and Merke
Publikováno v:
Adv Drug Deliv Rev
Skin pigmentation is a result of melanin produced by melanocytes in the epidermis. Melanocyte activity, along with the type and distribution of melanins, is the main driver for diversity of skin pigmentation. Dark melanin acts to protect against the
Publikováno v:
The Journal of investigative dermatology
Nervous system involvement in psoriasis pathogenesis is supported by increases in nerve fiber numbers and neuropeptides in psoriatic skin and by reports detailing spontaneous plaque remission following nerve injury. Using the KC-Tie2 psoriasiform mou
Publikováno v:
Journal of Biological Chemistry. 282:26832-26844
Epidemiological evidence suggests that long term treatment with hydroxymethylglutaryl-CoA reductase inhibitors, or statins, decreases the risk for developing Alzheimer disease (AD). However, statin-mediated AD protection cannot be fully explained by