Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephen M. Eggan"'
Autor:
Catherine E. Arnold, Logan J. Voegtly, Emily K. Stefanov, Matthew R. Lueder, Andrea E. Luquette, Robin H. Miller, Haven L. Miner, Andrew J. Bennett, Lindsay Glang, Tara N. McGinnis, Kristie E. Reisinger, Jae W. Dugan, Michael A. Mangat, Daniel J. Silberger, Rebecca L. Pavlicek, Chaselynn M. Watters, Gregory K. Rice, Francisco Malagon, Regina Z. Cer, Stephen M. Eggan, Kimberly A. Bishop-Lilly
Publikováno v:
Viruses, Vol 14, Iss 9, p 1918 (2022)
The global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the disparity between developed and developing countries for infectious disease surveillance and the sequencing of pathogen genomes. The majori
Externí odkaz:
https://doaj.org/article/e65356d9ce3b4229a750d599655b282a
Autor:
Allison A. Curley, Stephen M. Eggan, Matt S. Lazarus, Z. Josh Huang, David W. Volk, David A. Lewis
Publikováno v:
Neurobiology of Disease, Vol 50, Iss , Pp 179-186 (2013)
Markers of GABA neurotransmission are altered in multiple regions of the neocortex in individuals with schizophrenia. Lower levels of glutamic acid decarboxylase 67 (GAD67) mRNA and protein, which is responsible for most cortical GABA synthesis, are
Externí odkaz:
https://doaj.org/article/274da3c6e2bf42148748a65671eeabe2
Publikováno v:
Schizophrenia Research. 159:124-129
The deleterious effects of cannabis use in schizophrenia have been linked, in part, to underlying disturbances in endogenous cannabinoid signaling in the prefrontal cortex. However, while receptor autoradiography studies of the primary cannabinoid re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f09834776e798f0f36a4753afbf121a
https://doi.org/10.1016/j.schres.2014.07.017
https://doi.org/10.1016/j.schres.2014.07.017
Autor:
David W. Volk, Stephen M. Eggan, Allison A. Curley, David A. Lewis, Matt S. Lazarus, Z. Josh Huang
Publikováno v:
Neurobiology of Disease, Vol 50, Iss, Pp 179-186 (2013)
Markers of GABA neurotransmission are altered in multiple regions of the neocortex in individuals with schizophrenia. Lower levels of glutamic acid decarboxylase 67 (GAD67) mRNA and protein, which is responsible for most cortical GABA synthesis, are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce972478c3860bb2bcd3a248ee08e5e
https://doi.org/10.1016/j.nbd.2012.10.018
https://doi.org/10.1016/j.nbd.2012.10.018
Autor:
Z. Josh Huang, Matthew S. Lazarus, Samuel R. Stoyak, Stephen M. Eggan, David A. Lewis, David W. Volk, Jill R. Glausier
Publikováno v:
Biological Psychiatry. 71:114-119
Levels of cannabinoid 1 receptor (CB1R) messenger RNA (mRNA) and protein, which are expressed most heavily in the cholecystokinin class of γ-aminobutyric acid (GABA) neurons, are lower in the dorsolateral prefrontal cortex in schizophrenia, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb84b676fbede703f59b9fc825a5312c
https://doi.org/10.1016/j.biopsych.2011.09.014
https://doi.org/10.1016/j.biopsych.2011.09.014
Autor:
David A. Lewis, Stephen M. Eggan
Publikováno v:
Cerebral Cortex. 17:175-191
Delta-9-tetrahydrocannabinol (Delta9-THC) has profound effects on higher cognitive functions, and exposure to Delta9-THC has been associated with the appearance or exacerbation of the clinical features of schizophrenia. These actions appear to be med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a03d4d6fa9db5e2c7723b009ba9c11
https://doi.org/10.1093/cercor/bhj136
https://doi.org/10.1093/cercor/bhj136
Publikováno v:
American Journal of Psychiatry. 161:739-742
Inhibition mediated by gamma-aminobutyric acid at the axon initial segment of pyramidal neurons appears to be altered in the prefrontal cortex in schizophrenia. This study examined the densities and laminar distribution of axon initial segments label
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878625908545033fc78dc6f21e9dabb4
https://doi.org/10.1176/appi.ajp.161.4.739
https://doi.org/10.1176/appi.ajp.161.4.739
Publikováno v:
The American journal of psychiatry. 167(12)
Certain cognitive deficits in individuals with schizophrenia have been linked to disturbed gamma-aminobutyric acid (GABA) and glutamate neurotrans-mission in the prefrontal cortex. Thus, it is important to understand how the mechanisms that regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2d0ea529bd6e0f898f6563cddb6821
https://pubmed.ncbi.nlm.nih.gov/20889653
https://pubmed.ncbi.nlm.nih.gov/20889653
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 35(10)
We recently showed that measures of cannabinoid 1 receptor (CB1R) mRNA and protein were significantly reduced in dorsolateral prefrontal cortex (DLPFC) area 9 in schizophrenia subjects relative to matched normal comparison subjects. However, other st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a43edc854912bb1e64f0f4af6ce3c22
https://pubmed.ncbi.nlm.nih.gov/20555313
https://pubmed.ncbi.nlm.nih.gov/20555313
Publikováno v:
Neuroscience. 169(4)
Exposure to cannabis impairs cognitive functions reliant on the circuitry of the dorsolateral prefrontal cortex (DLPFC) and increases the risk of schizophrenia. The actions of cannabis are mediated via the brain cannabinoid 1 receptor (CB1R), which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c8f76e706dad117238a987d92ac490
https://pubmed.ncbi.nlm.nih.gov/20542094
https://pubmed.ncbi.nlm.nih.gov/20542094