Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Stephen M. Dombrowski"'
Autor:
Sara Qvarlander, Stephen M. Dombrowski, Dipankar Biswas, Suraj Thyagaraj, Francis Loth, Jun Yang, Mark G. Luciano
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985).
Pulsation of the cerebral blood flow (CBF) produces intercranial pressure (ICP) waves. The aim of this study is to determine if externally modifying ICP pulsatility alters parenchymal blood flow pulsatility. A cardiac-gated inflatable device was inse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e6eef3b670bdc4728795ccd381ca6f
https://pubmed.ncbi.nlm.nih.gov/36548513
https://pubmed.ncbi.nlm.nih.gov/36548513
Autor:
Irina Todorov, Dana Schneeberger, Jane Pernotto Ehrman, Tracy Segall, Kellie N Kirksey, Kathryn Barringer, Josie Znidarsic, Michael F. Roizen, Heather Blonsky, Anne Tang, Andrew Bang, Jamie Starkey, Judi Bar, Stephen M. Dombrowski, Linda Libertini, Mladen Golubic, Rocio Lopez, Jonathan Doyle
Publikováno v:
Pain Medicine: The Official Journal of the American Academy of Pain Medicine
Objective To evaluate the effectiveness of a multidisciplinary, nonpharmacological, integrative approach that uses shared medical appointments to improve health-related quality of life and reduce opioid medication use in patients with chronic pain. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498ecaec28d8038f64c6373071e1f532
https://pubmed.ncbi.nlm.nih.gov/33543263
https://pubmed.ncbi.nlm.nih.gov/33543263
Autor:
Syed Khalid, Sara Qvarlander, Ian Suk, Francis Loth, Suraj Thyagaraj, Jun Yang, Amir Manbachi, Serge El-Khoury, Mark G. Luciano, Stephen M. Dombrowski
Publikováno v:
Neurosurgery
BACKGROUND: We have previously reported a method and device capable of manipulating ICP pulsatility while minimally effecting mean ICP. OBJECTIVE: To test the hypothesis that different modulations of the intracranial pressure (ICP) pulse waveform wil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d575d0648ccff8f6e965c0a0e49c6ad3
https://europepmc.org/articles/PMC7666905/
https://europepmc.org/articles/PMC7666905/
Autor:
Anne Song, Alexander J. Federation, Leo J.Y. Kim, David T.W. Jones, Ana Fernandez Miñan, Laura McDonald, Mathieu Lupien, Susan Q. Ke, Lukas Chavez, Briana C. Prager, Sheila K. Singh, Peter B. Dirks, Borja L. Holgado, Kristian W. Pajtler, Yan Li, Till Milde, Marc Zapatka, Angel M. Carcaboso, Livia Garzia, Xiuxing Wang, Chao Jun Li, Kenneth Aldape, Christine Lee, Ian C. Scott, Xin Wang, Laura K. Donovan, Xiu-Wu Bian, Sylvia Doan, Stephen M. Dombrowski, Betty Luu, Michael D. Taylor, Adam Tropper, Vaidehi Mahadev, James E. Bradner, Ryan C. Gimple, Tyler E. Miller, Serap Erkek, Christopher G. Hubert, Daniel C. Factor, Kulandaimanuvel Antony Michaelraj, Stefan M. Pfister, Kelsey C. Bertrand, Jennifer Zuccaro, Zhiqin Huang, Yuan Yao Thompson, Hendrik Witt, Nada Jabado, Konstantin Okonechnikov, Paul A. Northcott, James J. Morrow, Senthuran Vijayarajah, Jeremy N. Rich, Susanne Gröbner, Andrey Korshunov, Vijay Ramaswamy, Sisi Lai, Stephen C. Mack, Alina Saiakhova, Annie Huang, Claudia L.L. Valentim, James T. Rutka, Eric Bouffet, Xiaochong Wu, Matthias Lienhard, Qiulian Wu, Jüri Reimand, Peter J. Houghton, Andrew R. Morton, Peter C. Scacheri, John J.Y. Lee, Marina Ryzhova, Patrick Sin-Chan, Peter Lichter, Stephen T. Keir, Marcel Kool
Publikováno v:
Nature
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Genomic sequencing has driven precision-based oncology therapy; however, the genetic drivers of many malignancies remain unknown or non-targetable, so alternative approaches to the identification of therapeutic leads are necessary. Ependymomas are ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14b43b01c6fec382bc89e653995fb58
https://doi.org/10.1038/nature25169
https://doi.org/10.1038/nature25169
Publikováno v:
Neurotherapeutics. 14:372-384
Brain tumors represent some of the most malignant cancers in both children and adults. Current treatment options target the majority of tumor cells but do not adequately target self-renewing cancer stem cells (CSCs). CSCs have been reported to resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4b189078d5bfa75c3ade71f993ba7b
https://doi.org/10.1007/s13311-017-0524-0
https://doi.org/10.1007/s13311-017-0524-0
Autor:
Wenchao Zhou, Qiulian Wu, Craig Horbinski, Yu Shi, Ashley N. Ferguson, Jeremy N. Rich, Kailin Yang, William A. Flavahan, David F. Kashatus, Shideng Bao, Xiaoguang Fang, Zhi Huang, Stephen M. Dombrowski, Qi Xie
Publikováno v:
Nature neuroscience
Brain tumor initiating cells (BTICs) co-opt the neuronal high affinity glucose transporter, GLUT3, to withstand metabolic stress. We investigated another mechanism critical to brain metabolism, mitochondrial morphology, in BTICs. BTIC mitochondria we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2bce7c4e442ed8c96508f2d0b78b24
http://europepmc.org/articles/PMC4376639
http://europepmc.org/articles/PMC4376639
Autor:
Mark G. Luciano, Serge El-Khoury, Stephen M. Dombrowski, Deepti Kamasamudram Guruprakash, Abhishek Deshpande, Natalie Krajcir, Chandra Krishnan, Jun Yang
Publikováno v:
Clinical Neurology and Neurosurgery. 115:1729-1734
Objectives The aim of this study was to examine lumbar CSF-VEGF levels from elderly patients with ventriculomegaly to evaluate the possible circadian or periodic concentration profile and relevance to the prediction of drainage response. Methods Lumb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5746832630f58cc03ec6a5d757d6dd03
https://doi.org/10.1016/j.clineuro.2013.03.017
https://doi.org/10.1016/j.clineuro.2013.03.017
Autor:
Mark G. Luciano, Serge El-Khoury, Jun Yang, Stephen M. Dombrowski, Sara Qvarlander, Francis Loth, Suraj Thyagaraj
Publikováno v:
Journal of neurosurgery. 126(5)
OBJECTIntracranial pressure (ICP) pulsations are generally considered a passive result of the pulsatility of blood flow. Active experimental modification of ICP pulsations would allow investigation of potential active effects on blood and CSF flow an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1992b695aac97c5f0f819c75c66dc24a
https://pubmed.ncbi.nlm.nih.gov/27419825
https://pubmed.ncbi.nlm.nih.gov/27419825
Autor:
Mark G. Luciano, Natalie Krajcir, Abhishek Deshpande, Chandra Krishnan, Serge El-Khoury, Stephen M. Dombrowski, Jun Yang
Publikováno v:
Neurochemical Research. 36:1947-1954
Vascular endothelial growth factor (VEGF) is a promising biological marker and prognostic indicator in many neurological diseases. Although VEGF concentrations in plasma and cerebrospinal fluid (CSF) are increasingly reported, CSF-VEGF stability pre-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01b88ac5829fbfd7750bb392c99eeb5
https://doi.org/10.1007/s11064-011-0517-z
https://doi.org/10.1007/s11064-011-0517-z
Autor:
Rewa Arar, Anthony Mansour, Angel M. Carcaboso, Thamara Abou-Antoun, Stephen M. Dombrowski, Violette Recinos, Xiao-Nan Li, Jeremy N. Rich, Peter J. Houghton, Mohammad Movassaghi, Erin S. Murphy, Darell D. Bigner, Shuvojit Banerjee
Publikováno v:
Cancer Research. 78:A47-A47
Pediatric high-grade glioma (HGG), which ranks among the most lethal of cancers among children, contain two recurrent mutations within the histone H3 gene H3F3A (K27M and G34R/V). It is not known whether these mutations directly alter specific epigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60309dc134d8a6cc59f6b918cb8de20c
https://doi.org/10.1158/1538-7445.pedca17-a47
https://doi.org/10.1158/1538-7445.pedca17-a47