Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Stephen M Krone"'
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 4, p e1004874 (2016)
Reproduction in fishes and other vertebrates represents the timely coordination of many endocrine factors that culminate in the production of mature, viable gametes. In recent years there has been rapid growth in understanding fish reproductive biolo
Externí odkaz:
https://doaj.org/article/d0154848d96f4f9c9adcbafe501682d1
Autor:
Dilara Ally, Valorie R Wiss, Gail E Deckert, Danielle Green, Pavitra Roychoudhury, Holly A Wichman, Celeste J Brown, Stephen M Krone
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88702 (2014)
Most clinical and natural microbial communities live and evolve in spatially structured environments. When changes in environmental conditions trigger evolutionary responses, spatial structure can impact the types of adaptive response and the extent
Externí odkaz:
https://doaj.org/article/b6d76007a8f0415aae72c8bd41f5b9a9
Publikováno v:
Cells, Vol 13, Iss 7, p 585 (2024)
Recombination among different phages sometimes facilitates their ability to grow on new hosts. Protocols to direct the evolution of phage host range, as might be used in the application of phage therapy, would then benefit from including steps to ena
Externí odkaz:
https://doaj.org/article/a0271e3f8b964e79abf59746515a637a
Autor:
Stephen M. Krone, Beth M. Tuschhoff
Publikováno v:
PeerJ, Vol 10, p e12926 (2022)
We develop the mathematical structure of the neutral coalescent with both replication-dependent and replication-independent mutations. This allows us to explain and quantify empirical results that explore differences in genetic diversity in bacterial
Externí odkaz:
https://doaj.org/article/87dbaa4e87ab425a89f8709f052e6be8
Publikováno v:
Antibiotics, Vol 11, Iss 12, p 1709 (2022)
Background: The host ranges of individual phages tend to be narrow, yet many applications of phages would benefit from expanded host ranges. Empirical methods have been developed to direct the evolution of phages to attack new strains, but the method
Externí odkaz:
https://doaj.org/article/8bd0abbec73040078adf6e5a3341c137
Publikováno v:
Virus evolution. 8(2)
Defective interfering particles (DIPs) are naturally occurring viruses that have evolved to parasitize other viruses. They suppress wild-type (WT) virus infections through their role as intracellular parasites. Because most encode few or no viral pro
Publikováno v:
Evolution, Medicine, and Public Health
Background and objectivesGenetic engineering combined with CRISPR technology has developed to the point that gene drives can, in theory, be engineered to cause extinction in countless species. Success of extinction programs now rests on the possibili
Publikováno v:
Evolution, Medicine, and Public Health
Background and objectives Genetic engineering and similar technologies offer promising new approaches to controlling human diseases by blocking transmission from vectors. However, in spatially structured populations, imperfect coverage of the vector
Publikováno v:
Bulletin of Mathematical Biology
During an epidemic, the interplay of disease and opinion dynamics can lead to outcomes that are different from those predicted based on disease dynamics alone. Opinions and the behaviours they elicit are complex, so modelling them requires a measure