Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Stephen M Christensen"'
Autor:
Stephen M Christensen, Ashton T Belew, Najib M El-Sayed, Wagner L Tafuri, Fernando T Silveira, David M Mosser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007152 (2019)
Diffuse cutaneous leishmaniasis (DCL) is a rare form of leishmaniasis where parasites grow uncontrolled in diffuse lesions across the skin. Meta-transcriptomic analysis of biopsies from DCL patients infected with Leishmania amazonensis demonstrated a
Externí odkaz:
https://doaj.org/article/49f2f1354b8145489ae061877c407e3a
Autor:
Chirag Krishna, Joshua Chiou, Saori Sakaue, Joyce B. Kang, Stephen M. Christensen, Isac Lee, Melis Atalar Aksit, Hye In Kim, David von Schack, Soumya Raychaudhuri, Daniel Ziemek, Xinli Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Genetic variation in the human leukocyte antigen (HLA) loci is associated with risk of immune-mediated diseases, but the molecular effects of HLA polymorphism are unclear. Here we examined the effects of HLA genetic variation on the expressi
Externí odkaz:
https://doaj.org/article/68deecd756d04f759f1d94d794e8cfa3
Autor:
Stephen M Christensen, Laura A L Dillon, Lucas P Carvalho, Sara Passos, Fernanda O Novais, V Keith Hughitt, Daniel P Beiting, Edgar M Carvalho, Phillip Scott, Najib M El-Sayed, David M Mosser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 5, p e0005588 (2017)
[This corrects the article DOI: 10.1371/journal.pntd.0004992.].
Externí odkaz:
https://doaj.org/article/262fd8a16d9c4656b73e29de65da7b1f
Autor:
Stephen M Christensen, Laura A L Dillon, Lucas P Carvalho, Sara Passos, Fernanda O Novais, V Keith Hughitt, Daniel P Beiting, Edgar M Carvalho, Phillip Scott, Najib M El-Sayed, David M Mosser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 9, p e0004992 (2016)
Host and parasite gene expression in skin biopsies from Leishmania braziliensis-infected patients were simultaneously analyzed using high throughput RNA-sequencing. Biopsies were taken from 8 patients with early cutaneous leishmaniasis and 17 patient
Externí odkaz:
https://doaj.org/article/bb0256dc2d5a46f3b743829cc856a81b
Autor:
Gail A. West, Shuai Zhao, Quang Tam Nguyen, Stephen M. Christensen, Ilyssa O. Gordon, Stefan D. Holubar, Kellie M. Kravarik, Claudio Fiocchi, Pranab K. Mukherjee, Florian Rieder
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102686- (2023)
Summary: Single-cell isolation techniques allow the investigation of physical and functional relationships between individual cells within a complex cell population. Here, we present a protocol for single-cell isolation from full-thickness intestinal
Externí odkaz:
https://doaj.org/article/d6d3a645def64a3bac390c7b218bc539
Autor:
Alexandra Argyriou, Marc H. Wadsworth, Adrian Lendvai, Stephen M. Christensen, Aase H. Hensvold, Christina Gerstner, Annika van Vollenhoven, Kellie Kravarik, Aaron Winkler, Vivianne Malmström, Karine Chemin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Antibodies against citrullinated proteins (ACPA) can divide rheumatoid arthritis patients but the difference in immune phenotype is not clear. Here the authors characterise T peripheral helper cells in arthritic joints comparing ACPA+ and ACPA- patie
Externí odkaz:
https://doaj.org/article/7c4b331efe744bea9c025a9a5c5433f2
Autor:
Thomas Fabre, Alexander M. S. Barron, Stephen M. Christensen, Shoh Asano, Kathryn Bound, Matthew P. Lech, Marc H. Wadsworth, Xiao Chen, Chang Wang, Ju Wang, James McMahon, Franklin Schlerman, Alexis White, Kellie M. Kravarik, Andrew J. Fisher, Lee A. Borthwick, Kevin M. Hart, Neil C. Henderson, Thomas A. Wynn, Ken Dower
Publikováno v:
Science Immunology. 8
Macrophages are central orchestrators of the tissue response to injury, with distinct macrophage activation states playing key roles in fibrosis progression and resolution. Identifying key macrophage populations found in human fibrotic tissues could
Autor:
Thomas Fabre, Alexander M. S. Barron, Stephen M. Christensen, Shoh Asano, Marc H. Wadsworth, Xiao Chen, Ju Wang, James McMahon, Frank Schlerman, Alexis White, Kellie Kravarik, Andrew J. Fisher, Lee A. Borthwick, Kevin M. Hart, Neil C. Henderson, Thomas A. Wynn, Ken Dower
Macrophages are central orchestrators of the tissue response to injury, with distinct macrophage activation states playing key roles in the progression and resolution of fibrosis. Identifying the unique fibrogenic macrophages that are found in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8993673dee41aff8eae5e3ade2b4825
https://doi.org/10.1101/2022.07.01.498017
https://doi.org/10.1101/2022.07.01.498017
Autor:
Christopher K. E. Bleck, Peng Li, Rosanne Spolski, Leonard M. Neckers, Jian Xin Lin, Luca Gattinoni, Juan Carlos García-Cañaveras, Daniel Gromer, Ning Du, Stephen M. Christensen, Warren J. Leonard, Jessica Fioravanti, Suman Mitra, Joshua D. Rabinowitz, Rosa Nguyen, Jangsuk Oh, Sanjivan Gautam, Dalton Hermans, Risa Ebina-Shibuya, Sharon Veenbergen
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117, 6047-6055. National Academy of Sciences
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Proceedings of the National Academy of Sciences of the United States of America, 117, 6047-6055. National Academy of Sciences
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Interleukin (IL)-2 and IL-21 dichotomously shape CD8 + T cell differentiation. IL-2 drives terminal differentiation, generating cells that are poorly effective against tumors, whereas IL-21 promotes stem cell memory T cells (T SCM ) and antitumor res
Autor:
Alexandra, Argyriou, Marc H, Wadsworth, Adrian, Lendvai, Stephen M, Christensen, Aase H, Hensvold, Christina, Gerstner, Annika, van Vollenhoven, Kellie, Kravarik, Aaron, Winkler, Vivianne, Malmström, Karine, Chemin
Publikováno v:
Nature communications. 13(1)
Rheumatoid arthritis (RA) is an autoimmune disease affecting synovial joints where different CD4