Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen M, Mongovin"'
Autor:
Nathalie Esser, Christine Schmidt, Breanne M. Barrow, Laura Cronic, Daryl J. Hackney, Stephen M. Mongovin, Meghan F. Hogan, Andrew T. Templin, Joseph J. Castillo, Rebecca L. Hull, Sakeneh Zraika
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Treatment of heart failure with the angiotensin receptor-neprilysin inhibitor sacubitril/valsartan improved glycemic control in individuals with type 2 diabetes. The relative contribution of neprilysin inhibition versus angiotensin II receptor antago
Externí odkaz:
https://doaj.org/article/2ca52c5595b6419c9d324310bf524e62
Autor:
Nathalie, Esser, Stephen M, Mongovin, Jacqueline, Parilla, Breanne M, Barrow, Thomas O, Mundinger, Brendy S, Fountaine, Megan J, Larmore, Joseph J, Castillo, Rehana, Akter, Rebecca L, Hull, Sakeneh, Zraika
Publikováno v:
Am J Physiol Endocrinol Metab
Type 2 diabetes is associated with the upregulation of neprilysin, a peptidase capable of cleaving glucoregulatory peptides such as glucagon-like peptide-1 (GLP-1). In humans, use of the neprilysin inhibitor sacubitril in combination with an angioten
Autor:
Venus A. Wong, Raquel Herrero, Gustavo Matute-Bello, Thomas R. Martin, Stephen M. Mongovin, Anne B. Lipke
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 301:L60-L70
We have shown that febrile-range hyperthermia enhances lung injury and mortality in mice exposed to inhaled LPS and is associated with increased TNF-α receptor activity, suppression of NF-κB activity in vitro, and increased apoptosis of alveolar ep
Autor:
Venus A. Wong, Stephen M. Mongovin, Kiyoyasu Kurahashi, Raquel Herrero, Thomas R. Martin, Gustavo Matute-Bello, Anne B. Lipke
Publikováno v:
The Journal of Immunology. 184:3801-3813
Fever is common in critically ill patients and is associated with worse clinical outcomes, including increased intensive care unit mortality. In animal models, febrile-range hyperthermia (FRH) worsens acute lung injury, but the mechanisms by which th
Autor:
Amy Selk, Kimberly Ballman, Venus A. Wong, Stephen M. Mongovin, Osamu Kajikawa, Shu Min Lin, Thomas R. Martin, Charles W. Frevert, Mark M. Wurfel
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 31:162-170
CD14 is important in the clearance of bacterial pathogens from lungs. However, the mechanisms that regulate the expression of membrane CD14 (mCD14) on alveolar macrophages (AM) have not been studied in detail. This study examines the regulation of mC
Autor:
Osamu Kajikawa, Thomas R. Martin, Rebecca Fox-Dewhurst, Richard B. Goodman, Wes B. Wong, Stephen M. Mongovin, Martin C. Johnson, Venus A. Wong
Publikováno v:
Journal of Biological Chemistry. 271:10853-10858
GRO proteins are alpha-chemokine cytokines that attract neutrophils and stimulate the growth of a variety of cells. Previously, we observed that rabbit alveolar macrophages transcribe the genes for at least two GRO homologues. In order to study the r
Autor:
Stephen M. Mongovin, Venus A. Wong, Richard B. Goodman, Osamu Kajikawa, Thomas R. Martin, Martin C. Johnson
Publikováno v:
Gene. 151(1-2)
We cloned two rabbit GRO homologue cDNAs from a lipopolysaccharide-stimulated rabbit alveolar macrophage (AM) cDNA library. One cDNA contains the complete coding sequence for a new mature GRO protein, RabGRO, which shares 68, 78 and 70% amino-acid id
Autor:
Ann Moriarty, Didier J. Leturcq, Stephen M. Mongovin, John C. Mathison, Richard J. Ulevitch, Peter S. Tobias, Thomas R. Martin
Publikováno v:
Journal of leukocyte biology. 56(1)
The CD14 antigen was originally described as a differentiation antigen on mononuclear cells. The purpose of this study was to investigate the relationship between the appearance of surface CD14 and the acquisition of lipopolysaccharide (LPS) responsi