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Autor:
Yue, Wang, Ries J, Langley, Kyle, Tamshen, Stephen M, Jamieson, Man, Lu, Heather D, Maynard, Jo K, Perry
Publikováno v:
Bioconjugate chemistry. 31(6)
Growth hormone (GH) is a peptide hormone that mediates actions through binding to a cell surface GH receptor (GHR). The GHR antagonist, B2036, combines an amino acid substitution at 120 that confers GHR antagonist activity, with eight additional amin