Zobrazeno 1 - 10
of 280
pro vyhledávání: '"Stephen Leslie"'
Autor:
Genelle F Harrison, Laura Ann Leaton, Erica A Harrison, Katherine M Kichula, Marte K Viken, Jonathan Shortt, Christopher R Gignoux, Benedicte A Lie, Damjan Vukcevic, Stephen Leslie, Paul J Norman
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009059 (2022)
Highly polymorphic interaction of KIR3DL1 and KIR3DS1 with HLA class I ligands modulates the effector functions of natural killer (NK) cells and some T cells. This genetically determined diversity affects severity of infections, immune-mediated disea
Externí odkaz:
https://doaj.org/article/a40864831cbd4d36b90418c41972b80d
Autor:
Paul A Lyons, James E Peters, Federico Alberici, James Liley, Richard M. R. Coulson, William Astle, Chiara Baldini, Francesco Bonatti, Maria C Cid, Heather Elding, Giacomo Emmi, Jörg Epplen, Loïc Guillevin, David R. W. Jayne, Tao Jiang, Iva Gunnarsson, Peter Lamprecht, Stephen Leslie, Mark A. Little, Davide Martorana, Frank Moosig, Thomas Neumann, Sophie Ohlsson, Stefanie Quickert, Giuseppe A. Ramirez, Barbara Rewerska, Georg Schett, Renato A. Sinico, Wojciech Szczeklik, Vladimir Tesar, Damjan Vukcevic, The European Vasculitis Genetics Consortium, Benjamin Terrier, Richard A Watts, Augusto Vaglio, Julia U Holle, Chris Wallace, Kenneth G. C. Smith
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disorder characterised by asthma, eosinophilia and vasculitis. Here, the authors describe a genome-wide association study of EGPA that reveals clinical and genetic difference
Externí odkaz:
https://doaj.org/article/ff891c79b773423a95539793d707bc9a
Autor:
Richard Ahn, Damjan Vukcevic, Allan Motyer, Joanne Nititham, David McG. Squire, Jill A. Hollenbach, Paul J. Norman, Eva Ellinghaus, Rajan P. Nair, Lam C. Tsoi, Jorge Oksenberg, John Foerster, Wolfgang Lieb, Stephan Weidinger, Andre Franke, James T. Elder, Eric Jorgenson, Stephen Leslie, Wilson Liao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Killer cell immunoglobulin-like receptors (KIR) regulate immune responses in NK and CD8+ T cells via interaction with HLA ligands. KIR genes, including KIR2DS1, KIR3DL1, and KIR3DS1 have previously been implicated in psoriasis susceptibility. However
Externí odkaz:
https://doaj.org/article/be5b01fa959f4f46af42fb1812d00ced
Publikováno v:
Dermatology and Therapy, Vol 8, Iss 4, Pp 593-604 (2018)
Abstract Introduction Psoriatic arthritis (PsA) is a chronic, inflammatory arthritis that affects an estimated 30% of patients with psoriasis. PsA is underdiagnosed in primary care and dermatology clinics due to a variety of reasons, including failur
Externí odkaz:
https://doaj.org/article/3c561a2d9f204ef5bc5326afe61d6962
Autor:
Aimee L Hanson, International Genetics of Ankylosing Spondylitis Consortium, Damjan Vukcevic, Stephen Leslie, Jessica Harris, Kim-Anh Lê Cao, Tony J Kenna, Matthew A Brown
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008906 (2020)
The killer immunoglobulin-like receptors (KIRs), found predominantly on the surface of natural killer (NK) cells and some T-cells, are a collection of highly polymorphic activating and inhibitory receptors with variable specificity for class I human
Externí odkaz:
https://doaj.org/article/a58ae09307ae4049b897e5518dd861b1
Publikováno v:
Urology Case Reports, Vol 27, Iss , Pp - (2019)
Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells,
Externí odkaz:
https://doaj.org/article/0822cab3577b4610ac3ec0638af3deef