Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Stephen L. Minger"'
Autor:
Mitchell K.P. Lai, Shirley W.Y. Tsang, Monica Garcia-Alloza, Stephen L. Minger, James A.R. Nicoll, Margaret M. Esiri, Peter T.-H. Wong, Christopher P.L.-H. Chen, María J. Ramírez, Paul T. Francis
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 3, Pp 555-561 (2006)
The effects of the APOE ε4 allele on a range of pre- and postsynaptic cholinergic markers were studied in a cohort of community-based Alzheimer's disease (AD) patients. Compared with age-matched controls, the postmortem AD neocortex showed decreased
Externí odkaz:
https://doaj.org/article/d9dd82bb0f40413b9c101ae665723e85
Autor:
Carol Brayne, George M. Savva, Alyma Somani, Antigoni Ekonomou, Gillian Forster, Stephen L. Minger, Paul T. Francis, Elaine K. Perry, Clive Ballard, Johannes Attems, Mary Johnson
Publikováno v:
Ekonomou, A, Savva, G M, Brayne, C, Forster, G, Francis, P T, Johnson, M, Perry, E K, Attems, J, Somani, A, Minger, S L, Ballard, C G 2015, ' Stage-Specific Changes in Neurogenic and Glial Markers in Alzheimer's Disease ', Biological psychiatry, vol. 77, no. 8, pp. 711-719 . https://doi.org/10.1016/j.biopsych.2014.05.021
BackgroundReports of altered endogenous neurogenesis in people with Alzheimer’s disease (AD) and transgenic AD models have suggested that endogenous neurogenesis may be an important treatment target, but there is considerable discrepancy among stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8055aa72dc8b3eca6bb5243e3be52c48
https://doi.org/10.1016/j.biopsych.2014.05.021
https://doi.org/10.1016/j.biopsych.2014.05.021
Autor:
Sara Hall, R D Ramracheya, Stephen L. Minger, Shanta J. Persaud, Nicholas D. Evans, Helen M. Milne, Peter M. Jones, Christopher J. Burns
Mature beta-cells and nerve cells share many functional similarities despite originating from different embryonic germ layers. The aim of this study was to investigate the potential of neural stem cells (NSCs), isolated from foetal rat brain, as a st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3010bcfb24ee48466f83677f9d304637
https://doi.org/10.1016/j.bbrc.2004.11.062
https://doi.org/10.1016/j.bbrc.2004.11.062
Autor:
Margaret M. Esiri, William G. Honer, Tony Hope, Brendan McDonald, Stephen L. Minger, Paul T. Francis, James A. R. Nicoll, Janet Carter, Janet Keene
Publikováno v:
King's College London
Synaptic pathology is proposed to be integral to the clinical expression of Alzheimer disease (AD). Most studies have assessed only the vesicle protein synaptophysin as a measure of synaptic integrity. The interrelationships of synaptophysin, other p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b196d4dc7359728075d3da70b1c9eac5
https://ora.ox.ac.uk/objects/uuid:8e62632e-ebe7-43f4-87af-bcf6118c1a80
https://ora.ox.ac.uk/objects/uuid:8e62632e-ebe7-43f4-87af-bcf6118c1a80
Autor:
Raj N. Kalaria, Clive Ballard, Mark I. Johnson, Antigoni Ekonomou, Elaine K. Perry, Stephen L. Minger, Robert H. Perry
Publikováno v:
Neuropathology and Applied Neurobiology. 38:344-353
A. Ekonomou, M. Johnson, R. H. Perry, E. K. Perry, R. N. Kalaria, S. L. Minger and C. G. Ballard (2012) Neuropathology and Applied Neurobiology38, 344–353 Increased neural progenitors in individuals with cerebral small vessel disease Aims: Recent w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4274c8331293e7d05742299b82a9d05
https://doi.org/10.1111/j.1365-2990.2011.01224.x
https://doi.org/10.1111/j.1365-2990.2011.01224.x
Autor:
M. J. Cooke, Francesco Dell'Accio, Sarah Pringle, Stefan Przyborski, Stephen L. Minger, C. De Bari, Agamemnon E. Grigoriadis
Publikováno v:
Cell Proliferation. 44:120-127
Objectives: To characterize basal differentiation tendencies of a human embryonic stem (hES) cell line, KCL-002. Materials and methods: In vitro specification and differentiation of hES cells were carried out using embryoid body (EB) cultures and tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5b4f8b9b7bb32673e2d7c11f4b403dd
https://doi.org/10.1111/j.1365-2184.2011.00744.x
https://doi.org/10.1111/j.1365-2184.2011.00744.x
Autor:
Maria B. Goncalves, Marta Agudo, siobhan connor, Stephen B. McMahon, Jonathan Corcoran, Stephen L. Minger, Malcolm Maden
Publikováno v:
Developmental Biology. 326(2):305-313
We show here the role of retinoic acid receptor (RAR) beta and alpha signalling in proliferation and differentiation of endogenous adult forebrain neural progenitor cells (NPCs). RARbeta activation stimulates Sonic hedgehog signalling (Shh), and indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5d893eb522cfb3086eca71ed396c17
Autor:
Matthias Matzkies, Ulrich Mattheus, Sabine Conrad, Michael Bonin, Jürgen Hescheler, Lothar Just, Karl-Dietrich Sievert, Hans-Joachim Wagner, Hans-Jörg Bühring, Jörg Hennenlotter, Arnulf Stenzl, Stephen L. Minger, Markus Renninger, Thomas Skutella, Andreas F. Mack, Wilhelm K. Aicher, Tina Wiesner, Michael Reppel
Publikováno v:
Nature. 456:344-349
Human primordial germ cells and mouse neonatal and adult germline stem cells are pluripotent and show similar properties to embryonic stem cells. Here we report the successful establishment of human adult germline stem cells derived from spermatogoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4849f645a34a0c6d3a30633039d06675
https://doi.org/10.1038/nature07404
https://doi.org/10.1038/nature07404
Publikováno v:
Regenerative Medicine. 2:929-945
Endogenous repair after injury in the adult CNS is limited by a number of factors including cellular loss, inflammation, cavitation and glial scarring. Spinal cord neural progenitor cells (SCNPCs) may provide a valuable cellular source for promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d88544081fc32c27c2ebf0cd80f3f2
https://doi.org/10.2217/17460751.2.6.929
https://doi.org/10.2217/17460751.2.6.929
Autor:
Nissim Benvenisty, Minal Patel, Glyn Stacey, Lesley Young, Sanna Vuoristo, Barak Blum, Robert Passier, Steve Oh, Rebecca S. Hamilton, Miodrag Stojkovic, Barbara B. Knowles, Benjamin Reubinoff, Kehkooi Kee, Barbara S. Mallon, Andras Nagy, Michal Amit, Janet Rossant, Paul J. Gokhale, Franck Lebrin, Henrike Siemen, Simon Bevan, Weidong Zhang, Milla Mikkola, Stephen L. Minger, Norio Nakatsuji, Peter W. Andrews, Eric S Sherrer, Paul Bello, Tikva Turetsky, Lorraine S. Berry, Behrouz Aflatoonian, Christine L. Mummery, Masha Mileikovsky, Yoav Mayshar, Angela Ford, Harry Moore, Mark Jones, Joseph Itskovitz-Eldor, Jackie Johnson, Lars Ährlund-Richter, Roland A. Fleck, Oluseun Adewumi, Jamie P. Jackson, Alex Hampl, Andre Bh Choo, Petr Dvorak, Timo Otonkoski, Daisy Manning, Henrik Semb, Marta P. Imreh, Justin Brooking, Marina Gertsenstein, Dorien Ward, Jin P. Szatkiewicz, Timo Tuuri, Thomas C Schulz, Marian S Piekarczyk, Kevin G. Chen, Karin Astrid Maria Gertow, Renee A. Reijo Pera, Thomas A Weaver, Gemma Beighton, Kye-Yoon Park, Majlinda Lako, Ronald D.G. McKay, Katarina Emanuelsson, Cia Olsson, Carmel M. O’Brien, Johan Hyllner, Hema Patel, Outi Hovatta, Allan J. Robins, Hirofumi Suemori, Peter J. Rugg-Gunn, Martin F. Pera, Marie Corbel, Gary A. Churchill, Ivan Damjanov, John S Draper, Benjamin L. King, Lyn Healy, Steineke van den Brink, Roger A. Pedersen, Anna E. Michalska, Kristina Vintersten
Publikováno v:
Nature Biotechnology. 25:803-816
The International Stem Cell Initiative characterized 59 human embryonic stem cell lines from 17 laboratories worldwide. Despite diverse genotypes and different techniques used for derivation and maintenance, all lines exhibited similar expression pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867a067cc25cab7204dd3712d4e89593
https://doi.org/10.1038/nbt1318
https://doi.org/10.1038/nbt1318