Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stephen L. Gasior"'
Autor:
Zhenglin Hou, Rimante Zedaveinyte, Joshua K. Young, Sushmitha Paulraj, Arunas Silanskas, Greta Bigelyte, Virginijus Siksnys, Vesna Djukanovic, Karolina Budre, Tautvydas Karvelis, Česlovas Venclovas, Stephen L. Gasior
Publikováno v:
Nucleic acids research, Oxford : Oxford University Press, 2020, first on line, p. [1-8]
Nucleic acids research, Oxford : Oxford University Press, 2020, vol. 48, iss. 9, p. 5016-5023
Nucleic Acids Research
Nucleic acids research, Oxford : Oxford University Press, 2020, vol. 48, iss. 9, p. 5016-5023
Nucleic Acids Research
In recent years, CRISPR-associated (Cas) nucleases have revolutionized the genome editing field. Being guided by an RNA to cleave double-stranded (ds) DNA targets near a short sequence termed a protospacer adjacent motif (PAM), Cas9 and Cas12 offer u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d247b0d5509d3ee33c07486670fba61
https://repository.vu.lt/VU:ELABAPDB55056678&prefLang=en_US
https://repository.vu.lt/VU:ELABAPDB55056678&prefLang=en_US
Autor:
Rodolphe Barrangou, Lijuan Wang, Joshua K. Young, Pedro Navarro, Stephen L. Gasior, Becca Vickroy, Spencer Jones
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-7 (2019)
Communications Biology
Communications Biology
CRISPR-Cas systems are robust and facile tools for manipulating the genome, epigenome and transcriptome of eukaryotic organisms. Most groups use class 2 effectors, such as Cas9 and Cas12a, however, other CRISPR-Cas systems may provide unique opportun
Autor:
Stephen L. Gasior, Zhenglin Hou, Virginijus Siksnys, Greta Bigelyte, Vesna Djukanovic, Joshua K. Young, Arunas Silanskas, Česlovas Venclovas, Rimante Zedaveinyte, Sushmitha Paulraj, Karolina Budre, Tautvydas Karvelis
In recent years, CRISPR-associated (Cas) nucleases have revolutionized the genome editing field. Being guided by an RNA to cleave double-stranded (ds) DNA targets near a short sequence termed a protospacer adjacent motif (PAM), Cas9 and Cas12 offer u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae7b83f3950dd003dc996178de31ff0
https://doi.org/10.1101/654897
https://doi.org/10.1101/654897
Autor:
Barbara Truman, Rachel A. Umoren, Stephen L. Gasior, Carolyn Lowe, Dora J. Stadler, Deema Al-Sheikhly
Publikováno v:
Innovations in Global Medical and Health Education. 2014
Certain aspects of healthcare education are difficult to teach in real world environments or in isolated classroom settings. These include, but are not limited to, collaboration and interdisciplinary teamwork skills that are necessary for improved te
Autor:
Uy Ear, Ralph R. Weichselbaum, Stephen L. Gasior, Heidi Olivares, Danielle M. Hari, Douglas K. Bishop
Publikováno v:
Proceedings of the National Academy of Sciences. 98:8411-8418
Members of the RecA family of recombinases from bacteriophage T4, Escherichia coli , yeast, and higher eukaryotes function in recombination as higher-order oligomers assembled on tracts of single-strand DNA (ssDNA). Biochemical studies have shown tha
Publikováno v:
Genes & Development. 12:2208-2221
We show that the Saccharomyces cerevisiae recombination protein Rad52 and the single-strand DNA-binding protein RPA assemble into cytologically detectable subnuclear complexes (foci) during meiotic recombination. Immunostaining shows extensive coloca
Autor:
Nicholas A. Wallace, Stephen L. Gasior, Prescott L. Deininger, Zachary J Faber, Heather L. Howie, Denise A. Galloway
Publikováno v:
Virology. 443(1)
The expression of the E6 protein from certain members of the HPV genus β (β HPV 5 and 8 E6) can disrupt p53 signaling by diminishing the steady state levels of two p53 modifying enzymes, ATR and p300. Here, we show that β-HPV 5 and 8 E6 are also c
Autor:
Graeme Preston, Nicolas Gilbert, John V. Moran, Stephen L. Gasior, Prescott L. Deininger, Dale J. Hedges
Publikováno v:
Gene
Gene, Elsevier, 2007, 390 (1-2), pp.190-198. ⟨10.1016/j.gene.2006.08.024⟩
Gene, Elsevier, 2007, 390 (1-2), pp.190-198. ⟨10.1016/j.gene.2006.08.024⟩
The human Long Interspersed Element-1 (LINE-1) and the Short Interspersed Element (SINE) Alu comprise 28% of the human genome. They share the same L1-encoded endonuclease for insertion, which recognizes an A+T-rich sequence. Under a simple model of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e46b2d9e1c93ae0039ab9d6c5c077c
https://europepmc.org/articles/PMC1850991/
https://europepmc.org/articles/PMC1850991/
Publikováno v:
Analytical biochemistry. 349(1)
RNA interference has become a powerful tool for specific inhibition of gene expression in mammalian cells. Expression constructs allow for the long-term delivery of short interfering RNAs, usually through the expression of Pol III-transcribed hairpin
Two RecA homologs, Rad51 and Dmc1, assemble as cytologically visible complexes (foci) at the same sites on meiotic chromosomes. Time course analysis confirms that co-foci appear and disappear as the single predominant form. A large fraction of co-foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300352fadbc1d0e294f5abcea215a34b
https://europepmc.org/articles/PMC27106/
https://europepmc.org/articles/PMC27106/