Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen L. Dickinson"'
Publikováno v:
Journal of psychopharmacology (Oxford, England). 4(2)
The behavioural effects of the specific and selective α2-adrenoreceptor antagonists, idazoxan, efaroxan and RX811059, have been investigated in the rat. All three drugs induced periods of behavioural activation characterized by increased locomotion
Publikováno v:
Neurochemistry International. 20:307-313
Whilst the CNS effects of thyrotropin releasing hormone (TRH) may result from a direct action on neurones it is also a possibility that another cell type may mediate an indirect action. A potential candidate for such a role is the astrocyte. The abil
Publikováno v:
Journal of Psychopharmacology. 5:187-195
The α2-adrenoceptor antagonists idazoxan and RX811059 induced reciprocal forepaw treading, a component of the 5-HT-behavioural syndrome in rats. This response is independent of 'non-α2-adrenoceptor idazoxan binding sites' (NAIBS) at which RX811059
Publikováno v:
Brain Research. 330:253-263
Responses to drugs affecting 5-hydroxytryptamine (5-HT) and dopaminergic (DA) system have been examined in rats after repeated immobilization. Groups of rats were immobilized for 2 h per day for up to 7 days. Twenty-four hours later their behavioural
Autor:
Paul Slater, Stephen L. Dickinson
Publikováno v:
Peptides. 1:293-299
Chronic administration of 1-prolyl-l-leucyl-glycinamide (MIF-I) to mice slightly reduced morphine's antinociceptive activity in the hot-plate test and modified the biphasic motor activity response to morphine. MIF-I antagonized the initial depression
Publikováno v:
Brain Research. 345:10-18
The effect of chronic corticosterone treatment (50 mg/kg s.c. 2 × daily) for up to 4 days on behavioural responses to drugs affecting 5-hydroxytryptamine (5-HT) and dopamine (DA) systems was examined in rats 20 h after the last treatment, when place
Publikováno v:
Psychopharmacology. 96:521-527
The importance of dopamine (DA) in mediating locomotor, exploratory and stereotyped behaviour in rodents is well established. Evidence also indicates a modulatory role for noradrenaline (NA) although, due to nonspecificity. of previously available ag
Publikováno v:
European Journal of Pharmacology. 119:143-152
Rats were immobilised for 2 h/day. Twenty four hours after the 1, 3 or 7 immobilisation periods they were injected with the 5HT agonist 5-methoxy-N,N-dimethyltryptamine (5MeODMT; 5 mg/kg i.p.) and behavioural responses (i.e. hind limb abduction, fore