Zobrazeno 1 - 10
of 452
pro vyhledávání: '"Stephen L Leib"'
Autor:
Janine Lux, Hannah Portmann, Lucía Sánchez García, Maria Erhardt, Lalaina Holivololona, Laura Laloli, Manon F. Licheri, Clement Gallay, Robert Hoepner, Nicholas J. Croucher, Daniel Straume, Jan-Willem Veening, Ronald Dijkman, Manfred Heller, Denis Grandgirard, Stephen L. Leib, Lucy J. Hathaway
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Treatment of pneumococcal infections is limited by antibiotic resistance and exacerbation of disease by bacterial lysis releasing pneumolysin toxin and other inflammatory factors. We identified a previously uncharacterized peptide in the Kle
Externí odkaz:
https://doaj.org/article/2a2b48dedc9249f1b222be17efc91b1a
Autor:
Janine Schwitter, Mattia Branca, Antonela Bicvic, Lena S. Abbuehl, Franziska Suter-Riniker, Stephen L. Leib, Anelia Dietmann
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionAn increasing number of studies demonstrate that viral meningitis and meningoencephalitis, even those with a mild course of meningitis, can result in residual sequelae.MethodsWe aimed to investigate the long-term outcome in both viral men
Externí odkaz:
https://doaj.org/article/ecc6696c100e40099de56d5f83b31d55
Autor:
Fanny Wegner, Blanca Cabrera-Gil, Araud Tanguy, Christiane Beckmann, Niko Beerenwinkel, Claire Bertelli, Matteo Carrara, Lorenzo Cerutti, Chaoran Chen, Samuel Cordey, Alexis Dumoulin, Louis du Plessis, Marc Friedli, Yannick Gerth, Gilbert Greub, Adrian Härri, Hans Hirsch, Cedric Howald, Michael Huber, Alexander Imhof, Laurent Kaiser, Verena Kufner, Stephen L. Leib, Karoline Leuzinger, Etleva Lleshi, Gladys Martinetti, Mirjam Mäusezahl, Milo Moraz, Richard Neher, Oliver Nolte, Alban Ramette, Maurice Redondo, Lorenz Risch, Lionel Rohner, Tim Roloff, Pascal Schläepfer, Katrin Schneider, Franziska Singer, Valeria Spina, Tanja Stadler, Erik Studer, Ivan Topolsky, Alexandra Trkola, Daniel Walther, Nadia Wohlwend, Cinzia Zehnder, Aitana Neves, Adrian Egli
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTDuring the SARS-CoV-2 pandemic, many countries directed substantial resources toward genomic surveillance to detect and track viral variants. There is a debate over how much sequencing effort is necessary in national surveillance programs for
Externí odkaz:
https://doaj.org/article/c4ccaa18016f452ba4419207aed44b4b
Autor:
Alexander Ernst, Indre Piragyte, Ayisha Marwa MP, Ngoc Dung Le, Denis Grandgirard, Stephen L. Leib, Andrew Oates, Nadia Mercader
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Drug repurposing is an important strategy in COVID-19 treatment, but many clinically approved compounds have not been extensively studied in the context of embryogenesis, thus limiting their administration during pregnancy. Here we used the
Externí odkaz:
https://doaj.org/article/3304dbc4c60f47f495335c5b6a8c0604
Autor:
Lena S. Abbuehl, Mattia Branca, Anamaria Ungureanu, Andrea Federspiel, Stephen L. Leib, Claudio L. A. Bassetti, Arsany Hakim, Anelia Dietmann
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundMagnetic resonance imaging (MRI) findings in meningoencephalitis have mainly been described in terms of their diagnostic value rather than their prognostic potential, except for herpes simplex virus (HSV) encephalitis. The aims of our study
Externí odkaz:
https://doaj.org/article/c6cfbcb47a6841ad86e29c80559401ed
Autor:
Gabriele Chiffi, Denis Grandgirard, Sabrina Stöckli, Luca G. Valente, Antoine Adamantidis, Stephen L. Leib
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Background/Aims Tick-borne encephalitis (TBE) is a disease affecting the central nervous system. Over the last decade, the incidence of TBE has steadily increased in Europe and Asia despite the availably of effective vaccines. Up to 50% of p
Externí odkaz:
https://doaj.org/article/8919a62c7a234d8a8251f1162bdfe242
Autor:
Miguel A. Terrazos Miani, Loïc Borcard, Sonja Gempeler, Christian Baumann, Pascal Bittel, Stephen L. Leib, Stefan Neuenschwander, Alban Ramette
Publikováno v:
Pathogens, Vol 13, Iss 1, p 61 (2024)
Whole-genome sequencing (WGS) represents the main technology for SARS-CoV-2 lineage characterization in diagnostic laboratories worldwide. The rapid, near-full-length sequencing of the viral genome is commonly enabled by high-throughput sequencing of
Externí odkaz:
https://doaj.org/article/f679f8d420324c5db1a59bce8793aeb6
Autor:
Ngoc Dung Le, Marel Steinfort, Denis Grandgirard, Aleksandra Maleska, David Leppert, Jens Kuhle, Stephen L. Leib
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract One-third of pneumococcal meningitis (PM) survivors suffer from neurological sequelae including learning disabilities and hearing loss due to excessive neuroinflammation. There is a lack of efficacious compounds for adjuvant therapy to contr
Externí odkaz:
https://doaj.org/article/2fd1aada1b5d47b99683246ef3ea9822
Autor:
Annelies Müller, Cebile Lekhuleni, Sabrina Hupp, Mignon du Plessis, Lalaina Holivololona, Eduard Babiychuk, Stephen L. Leib, Denis Grandgirard, Asparouh I. Iliev, Anne von Gottberg, Lucy J. Hathaway
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
IntroductionStreptococcus pneumoniae bacteria cause life-threatening invasive pneumococcal disease (IPD), including meningitis. Pneumococci are classified into serotypes, determined by differences in capsular polysaccharide and both serotype and pneu
Externí odkaz:
https://doaj.org/article/e3e92183b61e452f81a54b7fb7c2e7cf
Autor:
Anamaria Ungureanu, Julia van der Meer, Antonela Bicvic, Lena Abbuehl, Gabriele Chiffi, Léonore Jaques, Franziska Suter-Riniker, Stephen L. Leib, Claudio L. A. Bassetti, Anelia Dietmann
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Depending on geographic location, causes of encephalitis, meningoencephalitis and meningitis vary substantially. We aimed to identify the most frequent causes, clinical presentation and long-term outcome of encephalitis, meningoen
Externí odkaz:
https://doaj.org/article/1a679c0cbd284258be96087aea0d4a6d