Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Stephen L Johnson"'
Autor:
Robert C Tryon, Stephen L Johnson
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102317 (2014)
The study of regeneration in an in vivo vertebrate system has the potential to reveal targetable genes and pathways that could improve our ability to heal and repair damaged tissue. We have developed a system for clonal labeling of discrete cell line
Externí odkaz:
https://doaj.org/article/1591488e0b074b969ff609a8a9c07996
Autor:
Simon Perathoner, Jacob M Daane, Ulrike Henrion, Guiscard Seebohm, Charles W Higdon, Stephen L Johnson, Christiane Nüsslein-Volhard, Matthew P Harris
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004080 (2014)
The scaling relationship between the size of an appendage or organ and that of the body as a whole is tightly regulated during animal development. If a structure grows at a different rate than the rest of the body, this process is termed allometric g
Externí odkaz:
https://doaj.org/article/70696f579efe42d38c65d793b3a4db2b
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67801 (2013)
In order to facilitate understanding of pigment cell biology, we developed a method to concomitantly purify melanocytes, iridophores, and retinal pigmented epithelium from zebrafish, and analyzed their transcriptomes. Comparing expression data from t
Externí odkaz:
https://doaj.org/article/25092cce79294fc9ad2b770ab927afe7
Autor:
Zurab R Tsetskhladze, Victor A Canfield, Khai C Ang, Steven M Wentzel, Katherine P Reid, Arthur S Berg, Stephen L Johnson, Koichi Kawakami, Keith C Cheng
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47398 (2012)
A major challenge in personalized medicine is the lack of a standard way to define the functional significance of the numerous nonsynonymous, single nucleotide coding variants that are present in each human individual. To begin to address this proble
Externí odkaz:
https://doaj.org/article/da3862002040408fb9a144dce163ab1c
Publikováno v:
Frontiers in Psychology, Vol 2 (2011)
Ordinary variations in human infants’ attachment behaviors—their proclivity to seek and accept comfort from caregivers—are associated with a wide range of individual differences in psychological functioning in adults. The current investigation
Externí odkaz:
https://doaj.org/article/5b11fbfad1cc4fd284f6d6d895099642
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21010 (2011)
Previous research in zebrafish has demonstrated that embryonic and larval regeneration melanocytes are derived from separate lineages. The embryonic melanocytes that establish the larval pigment pattern do not require regulative melanocyte stem cell
Externí odkaz:
https://doaj.org/article/a87e9991a1904399b146653b30575a71
Publikováno v:
PLoS Genetics, Vol 5, Iss 11, p e1000744 (2009)
Relatively little is known about the generation of adult form. One complex adult trait that is particularly amenable to genetic and experimental analysis is the zebrafish pigment pattern, which undergoes extensive remodeling during post-embryonic dev
Externí odkaz:
https://doaj.org/article/75a933d57eb447459151e513aa051b32
Autor:
Keith A Hultman, Erine H Budi, Daniel C Teasley, Andrew Y Gottlieb, David M Parichy, Stephen L Johnson
Publikováno v:
PLoS Genetics, Vol 5, Iss 7, p e1000544 (2009)
Adult stem cells are responsible for maintaining and repairing tissues during the life of an organism. Tissue repair in humans, however, is limited compared to the regenerative capabilities of other vertebrates, such as the zebrafish (Danio rerio). A
Externí odkaz:
https://doaj.org/article/7aa332eac91340b3a76f1f3d1fa05901
Autor:
Susana S Lopes, Xueyan Yang, Jeanette Müller, Thomas J Carney, Anthony R McAdow, Gerd-Jörg Rauch, Arie S Jacoby, Laurence D Hurst, Mariana Delfino-Machín, Pascal Haffter, Robert Geisler, Stephen L Johnson, Andrew Ward, Robert N Kelsh
Publikováno v:
PLoS Genetics, Vol 4, Iss 3, p e1000026 (2008)
A fundamental problem in developmental biology concerns how multipotent precursors choose specific fates. Neural crest cells (NCCs) are multipotent, yet the mechanisms driving specific fate choices remain incompletely understood. Sox10 is required fo
Externí odkaz:
https://doaj.org/article/f89e23d958bc4722af8d568b44265ef5
Publikováno v:
PLoS Genetics, Vol 3, Iss 6, p e88 (2007)
The establishment of a single cell type regeneration paradigm in the zebrafish provides an opportunity to investigate the genetic mechanisms specific to regeneration processes. We previously demonstrated that regeneration melanocytes arise from cell
Externí odkaz:
https://doaj.org/article/b246479196db4b339c15afc5b008194d