Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stephen Keysar"'
Autor:
Wei Liu, Hongchao Cao, Jing Wang, Areeg Elmusrati, Bing Han, Wei Chen, Ping Zhou, Xiyao Li, Stephen Keysar, Antonio Jimeno, Cun-Yu Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Histone lysine methyltransferase 2D (KMT2D) is the most frequently mutated epigenetic modifier in head and neck squamous cell carcinoma (HNSCC). However, the role of KMT2D in HNSCC tumorigenesis and whether its mutations confer any therapeut
Externí odkaz:
https://doaj.org/article/2acb42a0ff5e40cf83170523fb94604f
Autor:
Jennifer A. Low, Nisha Nanda, Michele Fernandes, Brian B. Tuch, Deborah Morosini, Philip J. Stephens, Yali Li, Dara L. Aisner, Marileila Varella-Garcia, Antonio Jimeno, Stephen Keysar, Adriana Estrada-Bernal, Anh T. Le, Aria Vaishnavi, Lara E. Davis, Robert C. Doebele
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a66340cae723397120cc48c8d7507e
https://doi.org/10.1158/2159-8290.22529550.v1
https://doi.org/10.1158/2159-8290.22529550.v1
Autor:
Jennifer A. Low, Nisha Nanda, Michele Fernandes, Brian B. Tuch, Deborah Morosini, Philip J. Stephens, Yali Li, Dara L. Aisner, Marileila Varella-Garcia, Antonio Jimeno, Stephen Keysar, Adriana Estrada-Bernal, Anh T. Le, Aria Vaishnavi, Lara E. Davis, Robert C. Doebele
Supplementary Figure 1. Structure of LOXO-101. Supplementary Figure 2. Schematic for TRK-SHC1 proximity ligation assay (PLA). Supplementary Figure 3. Validation of the TRK-SHC1 PLA. Supplementary Figure 4. TRK and ALK PLA in an ALK+ tumor sample. Sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2127ca5310438ad8be46daccfdd01122
https://doi.org/10.1158/2159-8290.22529547.v1
https://doi.org/10.1158/2159-8290.22529547.v1
Autor:
John J, Arcaroli, W M, Tai, Ryan, McWilliams, Stacey, Bagby, Patrick J, Blatchford, Marileila, Varella-Garcia, Alicia, Purkey, Kevin S, Quackenbush, Eun-Kee, Song, Todd M, Pitts, Dexiang, Gao, Chris, Lieu, Martine, McManus, Aik Choon, Tan, Xianxian, Zheng, Qin, Zhang, Mark, Ozeck, Peter, Olson, Zhi-Qin, Jiang, Scott, Kopetz, Antonio, Jimeno, Stephen, Keysar, Gail, Eckhardt, Wells A, Messersmith
Publikováno v:
International journal of cancer. 138(1)
Dysregulation of the Notch1 receptor has been shown to facilitate the development and progression of colorectal cancer (CRC) and has been identified as an independent predictor of disease progression and worse survival. Although mutations in the NOTC