Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen Kaesshaefer"'
Autor:
Claudio Scuoppo, Gerald Falchook, Elisa Fontana, Anja Williams, Nehal Lakhani, Jeff Evans, Fabio Iwamoto, Meredith McKean, Stefan Symeonides, Alistair McLaren, Jason Henry, Gina Capiaux, Robert Michel, Stephen Kaesshaefer, Alice Bexon, Jim Rotolo
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
T.R. Jeffry Evans, Nehal J. Lakhani, Hendrik-Tobias Arkenau, Meredith McKean, Stefan N. Symeonides, Fabio Massaiti Iwamoto, Jim Rotolo, Gina Capiaux, Rob Michel, Stephen Kaesshaefer, Alice Susannah Bexon, Gerald Steven Falchook
Publikováno v:
Journal of Clinical Oncology. 40:3014-3014
3014 Background: The oncogenic transcription factor CCAAT/enhancer-binding protein β (C/EBPβ) promotes tumor survival and proliferation and inhibits differentiation. ST101 is a peptide antagonist of C/EBPβ, with anti-tumor activity in prostate can
Autor:
Jose Lutzky, Thomas Urban Marron, Steven Francis Powell, Daniel H. Johnson, Manish Patel, Anthony B. El-Khoueiry, John Sarantopoulos, Saida Dadi-Mehmetaj, Luke Russell, Stephen J. Russell, Kah Whye Peng, Stephen Kaesshaefer, Giuseppe Gullo, Alice Susannah Bexon, Mario Sznol
Publikováno v:
Journal of Clinical Oncology. 40:TPS9595-TPS9595
TPS9595 Background: There is a need for novel immunotherapies to address the patient population that never or no longer responds to immune checkpoint inhibitors (CPI). VV1 is an oncolytic vesicular stomatitis virus engineered to express human interfe
Autor:
Alice S Bexon, Hendrik-Tobias Arkenau, Jeff Evans, Gerald S Falchook, Stefan N Symeonides, Meredith A McKean, Elisa Fontana, Manojkumar Bupath, Alistair McLaren, Sreenivasa Chandana, Tze-en Ding, Emerson A Lim, Jim Rotolo, Gina Capiaux, Rob Michel, Stephen Kaesshaefer, Nehal J Lakhani
Publikováno v:
Cancer Research. 82:OT2-01
Background: CCAAT/Enhancer Binding Protein Beta (C/EBPβ) is a transcription factor that is active during embryofetal development but held in an inactive state in most mature cells. C/EBPβ is upregulated or overactivated in multiple cancers, where i
Autor:
Nehal J. Lakhani, Hendrik-Tobias Arkenau, Stefan N. Symeonides, Jeffry Evans, Meredith A. McKean, Elisa Fontana, Manojkumar Bupath, Alistair McLaren, Sreenivasa Chandana, Tze-en Ding, Emerson A. Lim, Jim Rotolo, Gina Capiaux, Rob Michel, Stephen Kaesshaefer, Alice S. Bexon, Gerald S. Falchook
Publikováno v:
Molecular Cancer Therapeutics. 20:P06-03
Introduction: The oncogenic transcription factor CCAAT/enhancer-binding protein β (C/EBPβ) is normally active in embryofetal development, but inactive and suppressed in mature cells. Upregulation or activation of C/EBPβ in cancer promotes tumor su
Autor:
Jim A. Rotolo, Emerson A. Lim, Rob Michel, Hendrik-Tobias Arkenau, Gerald Steven Falchook, Alice Bexon, Stefan Symeonides, Jeff Evans, Gina Capiaux, Nehal Lakhani, Meredith McKean, Stephen Kaesshaefer
Publikováno v:
Neuro-Oncology. 23:vi71-vi71
BACKGROUND C/EBPβ is a transcription factor that is active during embryofetal development but held in an inactive state in most mature cells (Zahnow 2009). C/EBPβ is upregulated or overactivated in multiple cancers, where it inversely correlates wi
Autor:
Alysha N Newsom, Tessa Kroeninger, Nandakumar Packiriswamy, Stephen A. Boorjian, Bethany Brunton, Shruthi Naik, Bradley C. Leibovich, Kah Whye Peng, R. Jeffrey Karnes, Matthew K. Tollefson, Alice Bexon, Ena C. Whitelaw, Monica Reckner, Stephen Kaesshaefer, Timothy D. Lyon, Tanner Miest, Paul R. Young, Igor Frank, Mark L. Gonzalgo, Rosa Maria Diaz
Publikováno v:
Journal of Clinical Oncology. 38:TPS3172-TPS3172
TPS3172 Background: Bladder cancer is a leading cause of cancer death in the United States. Over 90% of bladder cancer cases are urothelial carcinomas (UC) that may present as a non-muscle-invasive (NMIBC) or muscle-invasive disease (MIBC). Standard
Autor:
Manish R. Patel, Israel Lowy, Luke Russell, Cheryl Stoner Brown, Naimish B. Pandya, Frank Seebach, Jose Lutzky, Stephen Kaesshaefer, Erol Wiegert, Steven Francis Powell, Alex A. Adjei, Mario Sznol, Steven J. O'Day, Rosa Maria Diaz, Giuseppe Gullo, Kah Whye Peng, Alice Bexon, Monica Reckner, Aiwu Ruth He
Publikováno v:
Journal of Clinical Oncology. 38:TPS3161-TPS3161
TPS3161 Background: VV1 is an oncolytic vesicular stomatitis virus engineered to express human IFNβ to enhance cellular anti-tumor immune responses and tumor selectivity, and the human sodium iodide symporter (NIS) for virus tracking by SPECT imagin