Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Stephen K. Van den Eeden"'
Autor:
Talar S. Habeshian, Kimberly L. Cannavale, Jeff M. Slezak, Yu-Hsiang Shu, Gary W. Chien, XuFeng Chen, Feng Shi, Kimberly D. Siegmund, Stephen K. Van Den Eeden, Jiaoti Huang, Chun R. Chao
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTAccurately identifying life-threatening prostate cancer (PCa) at time of diagnosis remains an unsolved problem. We evaluated whether DNA methylation status of selected candidate genes can predict the risk of metastasis beyond clinical risk fa
Externí odkaz:
https://doaj.org/article/e9339ab4917847d98550c4fbbffd952c
Autor:
Chun R. Chao, Jeff Slezak, Kimberly Siegmund, Kimberly Cannavale, Yu‐Hsiang Shu, Gary W. Chien, Xu‐Feng Chen, Feng Shi, Nan Song, Stephen K. Van Den Eeden, Jiaoti Huang
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18837-18849 (2023)
Abstract Background We used a genome‐wide discovery approach to identify methylation markers associated with metastasis in men with localized prostate cancer (PCa), as better identification of those at high risk of metastasis can inform treatment d
Externí odkaz:
https://doaj.org/article/7e2cb60011cb4623851ef31c8c7570c4
Autor:
Ana Babic, Michael H. Rosenthal, Tilak K. Sundaresan, Natalia Khalaf, Valerie Lee, Lauren K. Brais, Maureen Loftus, Leah Caplan, Sarah Denning, Anamol Gurung, Joanna Harrod, Khoschy Schawkat, Chen Yuan, Qiao-Li Wang, Alice A. Lee, Leah H. Biller, Matthew B. Yurgelun, Kimmie Ng, Jonathan A. Nowak, Andrew J. Aguirre, Sangeeta N. Bhatia, Matthew G. Vander Heiden, Stephen K. Van Den Eeden, Bette J. Caan, Brian M. Wolpin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Patients with pancreatic cancer commonly develop weight loss and muscle wasting. Whether adipose tissue and skeletal muscle losses begin before diagnosis and the potential utility of such losses for earlier cancer detection are not well unde
Externí odkaz:
https://doaj.org/article/cdfd07dd22ed47b9aca3132200d8cb87
Autor:
Hanna M. Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Selina M. Yogeshwar, Ryan P. Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, Guo Luo, Jing Zhang, Fang Han, Han Yan, Xiao Song Dong, Jing Li, Jun Zhang, Seung-Chul Hong, Tae Won Kim, Yves Dauvilliers, Lucie Barateau, Gert Jan Lammers, Rolf Fronczek, Geert Mayer, Joan Santamaria, Isabelle Arnulf, Stine Knudsen-Heier, May Kristin Lyamouri Bredahl, Per Medbøe Thorsby, Giuseppe Plazzi, Fabio Pizza, Monica Moresco, Catherine Crowe, Stephen K. Van den Eeden, Michel Lecendreux, Patrice Bourgin, Takashi Kanbayashi, Francisco J. Martínez-Orozco, Rosa Peraita-Adrados, Antonio Benetó, Jacques Montplaisir, Alex Desautels, Yu-Shu Huang, FinnGen, Poul Jennum, Sona Nevsimalova, David Kemlink, Alex Iranzo, Sebastiaan Overeem, Aleksandra Wierzbicka, Peter Geisler, Karel Sonka, Makoto Honda, Birgit Högl, Ambra Stefani, Fernando Morgadinho Coelho, Vilma Mantovani, Eva Feketeova, Mia Wadelius, Niclas Eriksson, Hans Smedje, Pär Hallberg, Per Egil Hesla, David Rye, Zerrin Pelin, Luigi Ferini-Strambi, Claudio L. Bassetti, Johannes Mathis, Ramin Khatami, Adi Aran, Sheela Nampoothiri, Tomas Olsson, Ingrid Kockum, Markku Partinen, Markus Perola, Birgitte R. Kornum, Sina Rueger, Juliane Winkelmann, Taku Miyagawa, Hiromi Toyoda, Seik-Soon Khor, Mihoko Shimada, Katsushi Tokunaga, Manuel Rivas, Jonathan K. Pritchard, Neil Risch, Zoltan Kutalik, Ruth O’Hara, Joachim Hallmayer, Chun Jimmie Ye, Emmanuel J. Mignot
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Narcolepsy type 1 (NT1) is caused by a loss of hypocretin/orexin transmission. Risk factors include pandemic 2009 H1N1 influenza A infection and immunization with Pandemrix®. Here, we dissect disease mechanisms and interactions with environ
Externí odkaz:
https://doaj.org/article/5ce5735744474cff8886bce42fe536b9
Autor:
Zeni Wu, Jessica L. Petrick, Andrea A. Florio, Chantal Guillemette, Laura E. Beane Freeman, Julie E. Buring, Gary Bradwin, Patrick Caron, Yu Chen, A. Heather Eliassen, Lawrence S. Engel, Neal D. Freedman, J. Michael Gaziano, Edward L. Giovannuci, Jonathan N. Hofmann, Wen-Yi Huang, Victoria A. Kirsh, Cari M. Kitahara, Jill Koshiol, I-Min Lee, Linda M. Liao, Christina C. Newton, Julie R. Palmer, Mark P. Purdue, Thomas E. Rohan, Lynn Rosenberg, Howard D. Sesso, Rashmi Sinha, Meir J. Stampfer, Caroline Y. Um, Stephen K. Van Den Eeden, Kala Visvanathan, Jean Wactawski-Wende, Anne Zeleniuch-Jacquotte, Xuehong Zhang, Barry I. Graubard, Peter T. Campbell, Katherine A. McGlynn
Publikováno v:
JHEP Reports, Vol 5, Iss 7, Pp 100742- (2023)
Background & Aims: Incidence rates of liver cancer in most populations are two to three times higher among men than women. The higher rates among men have led to the suggestion that androgens are related to increased risk whereas oestrogens are relat
Externí odkaz:
https://doaj.org/article/9ea728b893a84b6ead80ea0343ea52b6
Autor:
Philip C. Haycock, Maria Carolina Borges, Kimberley Burrows, Rozenn N. Lemaitre, Stephen Burgess, Nikhil K. Khankari, Konstantinos K. Tsilidis, Tom R. Gaunt, Gibran Hemani, Jie Zheng, Therese Truong, Brenda M. Birmann, Tracy OMara, Amanda B. Spurdle, Mark M. Iles, Matthew H. Law, Susan L. Slager, Fatemeh Saberi Hosnijeh, Daniela Mariosa, Michelle Cotterchio, James R. Cerhan, Ulrike Peters, Stefan Enroth, Puya Gharahkhani, Loic Le Marchand, Ann C. Williams, Robert C. Block, Christopher I. Amos, Rayjean J. Hung, Wei Zheng, Marc J. Gunter, George Davey Smith, Caroline Relton, Richard M. Martin, Nathan Tintle, Terri Rice, Iona Cheng, Mark Jenkins, Steve Gallinger, Alex J. Cornish, Amit Sud, Jayaram Vijayakrishnan, Margaret Wrensch, Mattias Johansson, Aaron D. Norman, Alison Klein, Alyssa Clay-Gilmour, Andre Franke, Andres V. Ardisson Korat, Bill Wheeler, Björn Nilsson, Caren Smith, Chew-Kiat Heng, Ci Song, David Riadi, Elizabeth B. Claus, Eva Ellinghaus, Evgenia Ostroumova, Hosnijeh, Florent de Vathaire, Giovanni Cugliari, Giuseppe Matullo, Irene Oi-Lin Ng, Jeanette E. Passow, Jia Nee Foo, Jiali Han, Jianjun Liu, Jill Barnholtz-Sloan, Joellen M. Schildkraut, John Maris, Joseph L. Wiemels, Kari Hemminki, Keming Yang, Lambertus A. Kiemeney, Lang Wu, Laufey Amundadottir, Marc-Henri Stern, Marie-Christine Boutron, Mark Martin Iles, Mark P. Purdue, Martin Stanulla, Melissa Bondy, Mia Gaudet, Lenha Mobuchon, Nicola J. Camp, Pak Chung Sham, Pascal Guénel, Paul Brennan, Philip R. Taylor, Quinn Ostrom, Rachael Stolzenberg-Solomon, Rajkumar Dorajoo, Richard Houlston, Robert B. Jenkins, Sharon Diskin, Sonja I. Berndt, Spiridon Tsavachidis, Stephen J. Channock, Tabitha Harrison, Tessel Galesloot, Ulf Gyllensten, Vijai Joseph, Y. Shi, Wenjian Yang, Yi Lin, Stephen K. Van Den Eeden
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104510- (2023)
Summary: Background: The causal relevance of polyunsaturated fatty acids (PUFAs) for risk of site-specific cancers remains uncertain. Methods: Using a Mendelian randomization (MR) framework, we assessed the causal relevance of PUFAs for risk of cance
Externí odkaz:
https://doaj.org/article/89940d7363ce43c781ea8d5c3c0a79fa
Autor:
Kathryn L. Taylor, George Luta, Vasiliki Zotou, Tania Lobo, Richard M. Hoffman, Kimberly M. Davis, Arnold L. Potosky, Tengfei Li, David Aaronson, Stephen K. Van Den Eeden
Publikováno v:
BJUI Compass, Vol 3, Iss 3, Pp 226-237 (2022)
Abstract Objectives In a prospective, comparative effectiveness study, we assessed clinical and psychological factors associated with switching from active surveillance (AS) to active treatment (AT) among low‐risk prostate cancer (PCa) patients. Me
Externí odkaz:
https://doaj.org/article/022ba926e5c94f2e95267fc13d2389b6
Autor:
Heather Spencer Feigelson, Christina L. Clarke, Stephen K. Van Den Eeden, Sheila Weinmann, Andrea N. Burnett-Hartman, Sarah Rowell, Shauna Goldberg Scott, Larissa L. White, Monica Ter-Minassian, Stacey A. A. Honda, Deborah R. Young, Aruna Kamineni, Terrence Chinn, Alexander Lituev, Alan Bauck, Elizabeth A. McGlynn
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background The Kaiser Permanente Research Bank (KPRB) is collecting biospecimens and surveys linked to electronic health records (EHR) from approximately 400,000 adult KP members. Within the KPRB, we developed a Cancer Cohort to address issu
Externí odkaz:
https://doaj.org/article/5b68ef3078694d6c8d579bf6e53c21a7
Autor:
Stephen K. Van Den Eeden, Matthew H.E.M. Browning, Douglas A. Becker, Jun Shan, Stacey E. Alexeeff, G. Thomas Ray, Charles P. Quesenberry, Ming Kuo
Publikováno v:
Environment International, Vol 163, Iss , Pp 107174- (2022)
Background and objective: Prior studies have shown higher green cover levels are associated with beneficial health outcomes. We sought to determine if residential green cover was also associated with direct healthcare costs. Methods: We linked reside
Externí odkaz:
https://doaj.org/article/49427ab2d5734b75ae0d4f01acbe5360
Autor:
Rebecca E. Graff, Taylor B. Cavazos, Khanh K. Thai, Linda Kachuri, Sara R. Rashkin, Joshua D. Hoffman, Stacey E. Alexeeff, Maruta Blatchins, Travis J. Meyers, Lancelote Leong, Caroline G. Tai, Nima C. Emami, Douglas A. Corley, Lawrence H. Kushi, Elad Ziv, Stephen K. Van Den Eeden, Eric Jorgenson, Thomas J. Hoffmann, Laurel A. Habel, John S. Witte, Lori C. Sakoda
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
While genetic loci shared between cancer types have been identified, cross-cancer relationships for polygenic risk scores have not been well studied. Here, the authors have developed polygenic risk scores for 16 cancers in two large cohorts and ident
Externí odkaz:
https://doaj.org/article/c8c7f06feddc43b4892e0628726c8ee8