Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Stephen K. Tahir"'
Autor:
Stephen K. Tahir, Morey L. Smith, Paul Hessler, Lisa Roberts Rapp, Kenneth B. Idler, Chang H. Park, Joel D. Leverson, Lloyd T. Lam
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Venetoclax (ABT-199), a first-in-class orally bioavailable BCL-2-selective inhibitor, was recently approved by the FDA for use in patients with 17p-deleted chronic lymphocytic leukemia who have received prior therapy. It is also b
Externí odkaz:
https://doaj.org/article/50dd38d90f7d492b9bcfd36f4735ec83
Publikováno v:
BioTechniques, Vol 29, Iss 1, Pp 156-160 (2000)
We have developed a rapid [3H] colchicine competition-binding scintillation proximity assay (SPA) to evaluate antimitotic compounds that bind to the colchicine-binding site on tubulin. The premise of our assay is that compounds will compete with radi
Externí odkaz:
https://doaj.org/article/09710dc5545f42398e97d82ebc886ac7
Autor:
Jun Chen, Wei Wu, Stephen K. Tahir, Paul E. Kroeger, Saul H. Rosenberg, Lex M. Cowsert, Frank Bennett, Stanislaw Krajewski, Maryla Krajewska, Kate Welsh, John C. Reed, Shi-Chung Ng
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 2, Iss 3, Pp 235-241 (2000)
Survivin, a member of the inhibitor of apoptosis protein (IAP) family, is detected in most common human cancers but not in adjacent normal cells. Previous studies suggest that survivin associates with the mitotic spindle and directly inhibits caspase
Externí odkaz:
https://doaj.org/article/59fbb30bc5034417a9a1b3c18c1b0f2f
Autor:
Stephen K. Tahir, Emiliano Calvo, Benedito A. Carneiro, Junichiro Yuda, Aditya Shreenivas, Mojca Jongen-Lavrencic, Eelke Gort, Kenichi Ishizawa, Daniel Morillo, Carla Biesdorf, Morey Smith, Dong Cheng, Monica Motwani, David Sharon, Tamar Uziel, Dimple A. Modi, Fritz G. Buchanan, Susan Morgan-Lappe, Bruno C. Medeiros, Darren C. Phillips
Publikováno v:
Blood, 141(17), 2114-2126. American Society of Hematology
Activation of apoptosis in malignant cells is an established strategy for controlling cancer and is potentially curative. To assess the impact of concurrently inducing the extrinsic and intrinsic apoptosis-signaling pathways in acute myeloid leukemia
Autor:
Dimitri Semizarov, Rick Lesniewski, Guido Sauter, Stephen K. Tahir, Gang Wang, Mark G. Anderson, Charles Van Sant, Edward T. Olejniczak
Supplementary Table S3 from Integrative Genomic Analysis of Small-Cell Lung Carcinoma Reveals Correlates of Sensitivity to Bcl-2 Antagonists and Uncovers Novel Chromosomal Gains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f070759111d30eeaa00eabf58e85394
https://doi.org/10.1158/1541-7786.22520652
https://doi.org/10.1158/1541-7786.22520652
Autor:
Tamar Uziel, Yu Shen, Daniel H. Albert, Warren M. Kati, Anahita Bhathena, Terry Magoc, Michael Mitten, Stephen K. Tahir, Sha Jin, Richard J. Bellin, Denise M. Wilcox, Xiaoli Huang, Ziping Yang, Emily J. Faivre, Xiaoyu Lin, Lloyd T. Lam
Suppl. Figure 1. Caspase inhibitor prevents caspase 3/7 activity; Suppl. Figure 2. Levels of BIM, BAD, BAX and BAK silencing by siRNA; Suppl. Figure 3. mRNA and protein expression of BCL2 and BCLxl upon treatment with ABBV-075.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1dad5db1a75487ec658a49fed01fd1
https://doi.org/10.1158/1535-7163.22508502.v1
https://doi.org/10.1158/1535-7163.22508502.v1
Autor:
Steven W. Elmore, Chris Tse, Joel D. Leverson, Deepak Sampath, Heather Maecker, Saul H. Rosenberg, Scott L. Ackler, Haichao Zhang, Stephen K. Tahir, Alexander R. Shoemaker, Yu Shen, Morey Smith, Xiaoyu Lin, Paul Nimmer, Michael J. Mitten, Bernard Liu, Xiaoli Huang, Vivek Abraham, Sha Jin, Jun Chen
PDF file - 40K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2c37b6b6dd801b591e2466ba9d48a4
https://doi.org/10.1158/1535-7163.22497208
https://doi.org/10.1158/1535-7163.22497208
Autor:
Steven W. Elmore, Chris Tse, Joel D. Leverson, Deepak Sampath, Heather Maecker, Saul H. Rosenberg, Scott L. Ackler, Haichao Zhang, Stephen K. Tahir, Alexander R. Shoemaker, Yu Shen, Morey Smith, Xiaoyu Lin, Paul Nimmer, Michael J. Mitten, Bernard Liu, Xiaoli Huang, Vivek Abraham, Sha Jin, Jun Chen
PDF file - 78K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cb83ab1dce91e1962e4cf133b54b8a
https://doi.org/10.1158/1535-7163.22497211
https://doi.org/10.1158/1535-7163.22497211
Autor:
Dimitri Semizarov, Rick Lesniewski, Guido Sauter, Stephen K. Tahir, Gang Wang, Mark G. Anderson, Charles Van Sant, Edward T. Olejniczak
Cancer is a highly heterogeneous disease in terms of the genetic profile and the response to therapeutics. An early identification of a genomic marker in drug discovery may help select patients that would respond to treatment in clinical trials. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a93be6ecf2f02b04c78232a3c5db95
https://doi.org/10.1158/1541-7786.c.6542718.v1
https://doi.org/10.1158/1541-7786.c.6542718.v1
Autor:
Steven W. Elmore, Chris Tse, Joel D. Leverson, Deepak Sampath, Heather Maecker, Saul H. Rosenberg, Scott L. Ackler, Haichao Zhang, Stephen K. Tahir, Alexander R. Shoemaker, Yu Shen, Morey Smith, Xiaoyu Lin, Paul Nimmer, Michael J. Mitten, Bernard Liu, Xiaoli Huang, Vivek Abraham, Sha Jin, Jun Chen
PDF file - 77K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4246d1fdcd63851c0714efa3d05f46d0
https://doi.org/10.1158/1535-7163.22497205.v1
https://doi.org/10.1158/1535-7163.22497205.v1