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of 7
pro vyhledávání: '"Stephen K. Costa"'
Autor:
Stephen K. Costa, Katherine Antosca, Chapman N. Beekman, Rachel L. Peterson, Swathi Penumutchu, Peter Belenky
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Antibiotic-induced gut microbiome dysbiosis (AID) is known to be influenced by host dietary composition. However, how and when diet modulates gut dysbiosis remains poorly characterized. Thus, here, we utilize a multi-omics approach to charac
Externí odkaz:
https://doaj.org/article/702e8597c5f9497e9ebb839e6ed0ce66
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009338 (2021)
Host defense proteins (HDPs), aka defensins, are a key part of the innate immune system that functions by inserting into the bacterial membranes to form pores to kill invading and colonizing microorganisms. To ensure survival, microorganism such as S
Externí odkaz:
https://doaj.org/article/7d0e317d0d8d464fbcbf55ab1e6f9745
Autor:
John R. Schultz, Stephen K. Costa, Gorakhnath R. Jachak, Pooja Hegde, Matthew Zimmerman, Yan Pan, Michaele Josten, Chinedu Ejeh, Travis Hammerstad, Hans Georg Sahl, Pedro M. Pereira, Mariana G. Pinho, Véronique Dartois, Ambrose Cheung, Courtney C. Aldrich
Publikováno v:
Journal of medicinal chemistry. 65(20)
Nosocomial infections caused by resistant Gram-positive organisms are on the rise, presumably due to a combination of factors including prolonged hospital exposure, increased use of invasive procedures, and pervasive antibiotic therapy. Although anti
Publikováno v:
J Bacteriol
Antimicrobial peptides (AMPs) are one of the key immune responses that can eliminate pathogenic bacteria through membrane perturbation. As a successful skin commensal, Staphylococcus epidermidis can sense and respond to AMPs through the GraXRS two-co
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 3, p e1009338 (2021)
PLoS Pathogens, Vol 17, Iss 3, p e1009338 (2021)
Host defense proteins (HDPs), aka defensins, are a key part of the innate immune system that functions by inserting into the bacterial membranes to form pores to kill invading and colonizing microorganisms. To ensure survival, microorganism such as S
Autor:
Nadja B. Cech, Stephen K. Costa, Daniel A. Todd, Alan M. O’Neill, Livia S. Zaramela, Karsten Zengler, James A. Sanford, Alexander R. Horswill, Teruaki Nakatsuji, Shadi Khalil, Richard L. Gallo, Michael R. Williams, Ambrose L. Cheung, Marc C. Liggins, Heather L. Winter
Publikováno v:
Science translational medicine. 11(490)
Colonization of the skin by Staphylococcus aureus is associated with exacerbation of atopic dermatitis (AD), but any direct mechanism through which dysbiosis of the skin microbiome may influence the development of AD is unknown. Here, we show that pr
Publikováno v:
Journal of Bacteriology, Vol. 199, No 16 (2017) pp. e00271-17
Staphylococcus epidermidis is the leading cause of infections on indwelling medical devices worldwide. Intrinsic antibiotic resistance and vigorous biofilm production have rendered these infections difficult to treat and, in some cases, require the r