Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Stephen K. Anderson"'
Autor:
Robert Y. S. Cheng, Lisa A. Ridnour, Adelaide L. Wink, Ana L. Gonzalez, Elise L. Femino, Helene Rittscher, Veena Somasundaram, William F. Heinz, Leandro Coutinho, M. Cristina Rangel, Elijah F. Edmondson, Donna Butcher, Robert J. Kinders, Xiaoxian Li, Stephen T. C. Wong, Daniel W. McVicar, Stephen K. Anderson, Milind Pore, Stephen M. Hewitt, Timothy R. Billiar, Sharon A. Glynn, Jenny C. Chang, Stephen J. Lockett, Stefan Ambs, David A. Wink
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-12 (2023)
Abstract A strong correlation between NOS2 and COX2 tumor expression and poor clinical outcomes in ER breast cancer has been established. However, the mechanisms of tumor induction of these enzymes are unclear. Analysis of The Cancer Genome Atlas (TC
Externí odkaz:
https://doaj.org/article/5046eefbdac54f9198343a6b6f842146
Autor:
Hongchuan Li, Md Ahasanur Rahman, Michael Ruesch, Caprice D. Eisele, Erik M. Anderson, Paul W. Wright, Jennie Cao, Shashikala Ratnayake, Qingrong Chen, Chunhua Yan, Daoud Meerzaman, Roshini S. Abraham, Aharon G. Freud, Stephen K. Anderson
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113454- (2023)
Summary: Previous studies of the murine Ly49 and human KIR gene clusters implicated competing sense and antisense promoters in the control of variegated gene expression. In the current study, an examination of transcription factor genes defines an ab
Externí odkaz:
https://doaj.org/article/53ef519c8e7344d8ac994b0e279e76e5
Autor:
Erik M. Anderson, Stephen K. Anderson
Publikováno v:
Genes, Vol 15, Iss 2, p 252 (2024)
An abundance of antisense promoters in the vicinity of the transcriptional start site of coding genes suggests that they play an important role in gene regulation. The divergent transcription of housekeeping genes by a common central promoter region
Externí odkaz:
https://doaj.org/article/4f71013a42b6452bb5dd940e875c5a2e
Autor:
Elizabeth K. Graydon, Tonia L. Conner, Kim Dunham, Cara Olsen, Emilie Goguet, Si’Ana A. Coggins, Marana Rekedal, Emily Samuels, Belinda Jackson-Thompson, Matthew Moser, Alyssa Lindrose, Monique Hollis-Perry, Gregory Wang, Santina Maiolatesi, Yolanda Alcorta, Anatalio Reyes, Mimi Wong, Kathy Ramsey, Julian Davies, Edward Parmelee, Orlando Ortega, Mimi Sanchez, Sydney Moller, Jon Inglefield, David Tribble, Timothy Burgess, Robert O’Connell, Allison M. W. Malloy, Simon Pollett, Christopher C. Broder, Eric D. Laing, Stephen K. Anderson, Edward Mitre
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNatural killer (NK) cells can both amplify and regulate immune responses to vaccination. Studies in humans and animals have observed NK cell activation within days after mRNA vaccination. In this study, we sought to determine if baseline
Externí odkaz:
https://doaj.org/article/44b64d20627f4b7e934c54c095a2eca8
Autor:
Elizabeth K. Graydon, Allison M.W. Malloy, Kawthar Machmach, Peifang Sun, Dominic Paquin-Proulx, Stephen Lizewski, Rhonda Lizewski, Dawn L. Weir, Carl W. Goforth, Stephen K. Anderson, Andrew G. Letizia, Edward Mitre
Publikováno v:
Current Research in Immunology, Vol 4, Iss , Pp 100064- (2023)
This study tested the hypothesis that high frequencies of natural killer (NK) cells are protective against symptomatic SARS-CoV-2 infection. Samples were utilized from the COVID-19 Health Action Response for Marines study, a prospective, observationa
Externí odkaz:
https://doaj.org/article/4bfc31955d084980a10a82d06946100c
Autor:
Veena Somasundaram, Lisa A. Ridnour, Robert YS. Cheng, Abigail J. Walke, Noemi Kedei, Dibyangana D. Bhattacharyya, Adelaide L. Wink, Elijah F. Edmondson, Donna Butcher, Andrew C. Warner, Tiffany H. Dorsey, David A. Scheiblin, William Heinz, Richard J. Bryant, Robert J. Kinders, Stanley Lipkowitz, Stephen TC. Wong, Milind Pore, Stephen M. Hewitt, Daniel W. McVicar, Stephen K. Anderson, Jenny Chang, Sharon A. Glynn, Stefan Ambs, Stephen J. Lockett, David A. Wink
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102529- (2022)
Antitumor immune polarization is a key predictor of clinical outcomes to cancer therapy. An emerging concept influencing clinical outcome involves the spatial location of CD8+ T cells, within the tumor. Our earlier work demonstrated immunosuppressive
Externí odkaz:
https://doaj.org/article/861cead31d3f4ebb8be3e8669adfe0cf
Autor:
Belinda M. Jackson-Thompson, Emilie Goguet, Eric D. Laing, Cara H. Olsen, Simon Pollett, K. Monique Hollis-Perry, Santina E. Maiolatesi, Luca Illinik, Kathleen F. Ramsey, Anatalio E. Reyes, Yolanda Alcorta, Mimi A. Wong, Julian Davies, Orlando Ortega, Edward Parmelee, Alyssa R. Lindrose, Matthew Moser, Elizabeth Graydon, Andrew G. Letizia, Christopher A. Duplessis, Anuradha Ganesan, Kathleen P. Pratt, Allison M. Malloy, David W. Scott, Stephen K. Anderson, Andrew L. Snow, Clifton L. Dalgard, John H. Powers, David Tribble, Timothy H. Burgess, Christopher C. Broder, Edward Mitre
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background SARS-CoV-2 is a recently emerged pandemic coronavirus (CoV) capable of causing severe respiratory illness. However, a significant number of infected people present as asymptomatic or pauci-symptomatic. In this prospective assessme
Externí odkaz:
https://doaj.org/article/92bd135e155348ab950f477df74eb6d7
Autor:
Hong Lou, Joseph F. Boland, Hongchuan Li, Robert Burk, Meredith Yeager, Stephen K. Anderson, Nicolas Wentzensen, Mark Schiffman, Lisa Mirabello, Michael Dean
Publikováno v:
Cancers, Vol 14, Iss 19, p 4895 (2022)
The human papillomavirus (HPV) type 16 E7 oncogene is critical to carcinogenesis and highly conserved. Previous studies identified a preponderance of non-synonymous E7 variants amongst HPV16-positive cancer-free controls compared to those with cervic
Externí odkaz:
https://doaj.org/article/7e9dd33e1fa4446c8a6eb35d2f53053c
Autor:
Frederick J. Goodson-Gregg, Brian Rothbard, Amy Zhang, Paul W. Wright, Hongchuan Li, Victoria E. Walker-Sperling, Mary Carrington, Stephen K. Anderson
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
A complex system regulating HLA-C expression in NK cells, driven by an NK-specific promoter that produces alternatively spliced variants of the 5′-UTR has been recently identified. Exon content of the NK-specific 5′-UTR varies strikingly across H
Externí odkaz:
https://doaj.org/article/c925690f8eae457d8eb7c8f9a6010fae
Autor:
Christopher L. McGinity, Erika M. Palmieri, Veena Somasundaram, Dibyangana D. Bhattacharyya, Lisa A. Ridnour, Robert Y. S. Cheng, Aideen E. Ryan, Sharon A. Glynn, Douglas D. Thomas, Katrina M. Miranda, Stephen K. Anderson, Stephen J. Lockett, Daniel W. McVicar, David A. Wink
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7068 (2021)
The metabolic requirements and functions of cancer and normal tissues are vastly different. Due to the rapid growth of cancer cells in the tumor microenvironment, distorted vasculature is commonly observed, which creates harsh environments that requi
Externí odkaz:
https://doaj.org/article/bc1fc47034cc4b409f11cdaf4e353bb8