Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stephen Joseph Johnson"'
Autor:
Suzanne Ross Kesten, Hyacinth C. Akunne, Lawrence D. Wise, David Juergen Wustrow, Stephen Joseph Johnson, Thomas G. Heffner, Thomas A. Pugsley
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:561-566
Screening in a neurotensin (NT) receptor binding assay resulted in the discovery of compound 1 with NT receptor binding affinity of 450 nM. SAR studies that varied substituents on each aromatic ring and the linking 1,5-pentanedione chain lead to comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2aecb85e5cdaceb7e7bf9f843691629
https://doi.org/10.1016/s0960-894x(97)00067-x
https://doi.org/10.1016/s0960-894x(97)00067-x
Autor:
Stephen Joseph Johnson, Shelly A. Glase, Suzanne R. Kesten, Peter J. Manley, Lawrence D. Wise, Jon Wright, Thomas G. Heffner, Thomas A. Pugsley, Robert G. MacKenzie, Hyacinth C. Akunne
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1361-1366
A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamide dopamine (DA) D 3 receptor agonists has been identified. These compounds were found to be selective for DA D 3 over D 2 receptors and were shown to be partial to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b944dbffb56fd0b3f3b76b3ac650a3a3
https://doi.org/10.1016/0960-894x(96)00231-4
https://doi.org/10.1016/0960-894x(96)00231-4
Autor:
Stephen Joseph Johnson
Publikováno v:
The Journal of Organic Chemistry. 60:8089-8092
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff70a837b187d058200c924d3b82570d
https://doi.org/10.1021/jo00129a061
https://doi.org/10.1021/jo00129a061
Autor:
Walter H. Moos, Stephen Joseph Johnson, Sharie L. Myers, Michael R. Pavia, Suzanne R. Kesten, Roy D. Schwarz, Robert E. Davis, Sheila H. Hobbs, Linda L. Coughenour, David T. Dudley
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5c72bac365091fa5c5c42af714f78de
https://doi.org/10.1002/chin.199142186
https://doi.org/10.1002/chin.199142186
Autor:
Stephen Joseph Johnson
Publikováno v:
ChemInform. 22
Reexamination of the reaction of ortho esters with diamino-malconitrile (1) or 4,5-dicyanoimidazole (3a) revealed that 1-alkyl-4,5-dicyanoimidazoles 4a-f can be obtained in high yield in a one-pot procedure without any additional reagent. This simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e21205adea504a39365f2921866d31
https://doi.org/10.1002/chin.199136185
https://doi.org/10.1002/chin.199136185
Autor:
Stephen Joseph Johnson
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e07fd922cfacf4b7ad0d489e548f48c
https://doi.org/10.1002/chin.199615141
https://doi.org/10.1002/chin.199615141
Publikováno v:
The Journal of Organic Chemistry. 57:4746-4749
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc973541e3becdceeec61769403f0e96
https://doi.org/10.1021/jo00043a038
https://doi.org/10.1021/jo00043a038
Autor:
Michael R. Pavia, Roy D. Schwarz, Robert E. Davis, Linda L. Coughenour, Stephen Joseph Johnson, Sharie L. Myers, David T. Dudley, Walter H. Moss, Sheila H. Hobbs, Suzanne R. Kesten
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 1:147-150
An oxazolidinone analogue of pilocarpine demonstrates muscarinic agonist-like properties in vitro at the acetylcholine-receptor. Replacement of the carbon alpha to the carbonyl in pilocarpine with a nitrogen represents the most active 2-oxazolidinone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1986ad776c0f5bc246f691c5030b5ee2
https://doi.org/10.1016/s0960-894x(01)80787-3
https://doi.org/10.1016/s0960-894x(01)80787-3
Autor:
Stephen Joseph Johnson
Publikováno v:
Synthesis. 1991:75-78
Reexamination of the reaction of ortho esters with diamino-malconitrile (1) or 4,5-dicyanoimidazole (3a) revealed that 1-alkyl-4,5-dicyanoimidazoles 4a-f can be obtained in high yield in a one-pot procedure without any additional reagent. This simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::583955f472ab5f1c8a670ad4061ba1c5
https://doi.org/10.1055/s-1991-26384
https://doi.org/10.1055/s-1991-26384
Autor:
Leonard T. Meltzer, Bastiaan Johan Venhuis, Durk Dijkstra, Stephen Joseph Johnson, Thomas G. Heffner, David J. Wustrow, LD Wise, Håkan Wikström
Publikováno v:
Journal of Medicinal Chemistry, 46(4), 584-590. AMER CHEMICAL SOC
A series of analogues of 6-(NN-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one (6), an enone prodrug of the mixed DA D-1/D-2 agonist 5,6-diOH-DPAT (2), was synthesized. The pharmacological profiles of these new enones and their in vivo ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6e765b584a7fb5118c8a8f4cd86996
https://pubmed.ncbi.nlm.nih.gov/12570379
https://pubmed.ncbi.nlm.nih.gov/12570379