Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen James Moore"'
Autor:
Vaishnavi Rajagopal, Nina C Leksa, Ronald D Gorham, Siddharth Jindal, Soumya Vijayan Nair, Kevin E Knockenhauer, Joanne Chan, Tony S Byun, Courtney J Mercadante, Stephen James Moore, Sandip Panicker, Graham C Parry, Michael J Storek
Publikováno v:
Blood Advances.
Dysregulated activation of the complement system is implicated in the onset or progression of several diseases. Most clinical-stage complement inhibitors target the inactive complement proteins present at high concentrations in plasma, which increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30013ef29ccda532b9e9058e8880f768
https://doi.org/10.1182/bloodadvances.2022009028
https://doi.org/10.1182/bloodadvances.2022009028
Autor:
Marcela F. Pasetti, Les Baillie, Stephen James Moore, Ana L. Jorgensen, Gabriela Mellado-Sánchez, Theresa Gallagher, James P. Nataro
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007644 (2019)
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007644 (2019)
Bacillus anthracis and Yersinia pestis are zoonotic bacteria capable of causing severe and sometimes fatal infections in animals and humans. Although considered as diseases of antiquity in industrialized countries due to animal and public health impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15849a0edf538886c06430e5f8331f7c
https://pubmed.ncbi.nlm.nih.gov/31430284
https://pubmed.ncbi.nlm.nih.gov/31430284
Publikováno v:
Biological chemistry.
The role of proteases in cancer was originally thought to be limited to the breakdown of basement membranes and extracellular matrix (ECM), thereby promoting cancer cell invasion into surrounding normal tissues. It is now well understood that proteas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b945dd7e790e504b5ac7e8d6b3394b2
https://pubmed.ncbi.nlm.nih.gov/30913028
https://pubmed.ncbi.nlm.nih.gov/30913028
Autor:
Julie A. Musson, Rosemary J. Boyton, Daniel M. Altmann, Bernard Maillere, Stephen James Moore, Les Baillie, Rebecca J. Ingram, John H. Robinson, Karen K. Y. Chu, Theresa Gallagher, Ethel Diane Williamson, Stephanie Ascough
Publikováno v:
Frontiers in Microbiology, Vol 6 (2016)
Ascough, S, Ingram, R J, Chu, K K Y, Musson, J A, Moore, S J, Gallagher, T, Baillie, L, Williamson, E D, Robinson, J H, Maillere, B, Boyton, R J & Altmann, D M 2016, ' CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor ', Frontiers in Microbiology, vol. 6, 1506 . https://doi.org/10.3389/fmicb.2015.01506
Frontiers in Microbiology
Ascough, S, Ingram, R J, Chu, K K Y, Musson, J A, Moore, S J, Gallagher, T, Baillie, L, Williamson, E D, Robinson, J H, Maillere, B, Boyton, R J & Altmann, D M 2016, ' CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor ', Frontiers in Microbiology, vol. 6, 1506 . https://doi.org/10.3389/fmicb.2015.01506
Frontiers in Microbiology
Anthrax is an endemic infection in many countries, particularly in the developing world. The causative agent, Bacillus anthracis, mediates disease through the secretion of binary exotoxins. Until recently, research into adaptive immunity targeting th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cb31ccba73e33c17ba9d7ccc698e06
http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01506/full
http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01506/full
Autor:
Helen C. Flick-Smith, Brendan N. Neeson, Rebecca J. Ingram, Daniel M. Altmann, Stephen James Moore, Liliana Rodriguez, Helen S. Atkins, Les Baillie, Marcela F. Pasetti, Theresa B. Huwar, Dominic C. Jenner, Gabriela Mellado-Sánchez, James P. Nataro
Publikováno v:
Vaccine. 28:6740-6748
Studies have confirmed the key role of Bacillus anthracis protective antigen (PA) in the US and UK human anthrax vaccines. However, given the tripartite nature of the toxin, other components, including lethal factor (LF), are also likely to contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0676b7d22264fa7d97b77cb72f63722
https://doi.org/10.1016/j.vaccine.2010.07.075
https://doi.org/10.1016/j.vaccine.2010.07.075
Autor:
Helen S. Atkins, Stephen James Moore, James P. Nataro, Chiguang Feng, Ana L. Rodriguez, Leslie W.J. Baillie, Marcela F. Pasetti
Publikováno v:
Vaccine. 26:6083-6091
We previously demonstrated the ability of an orally administered attenuated Salmonella enterica serovar Typhimurium strain expressing the protective antigen (PA) of Bacillus anthracis to confer protection against lethal anthrax aerosol spore challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b92f1445f1b814803dd9553eb4035d
https://doi.org/10.1016/j.vaccine.2008.09.010
https://doi.org/10.1016/j.vaccine.2008.09.010
Autor:
Fei Han, Shouchun Liu, Stephen James Moore, Jennifer Richardson, Jason Gee, Annie Yang, Olga Vasiljeva, Margaret Nguyen, Luc R. Desnoyers, Kenneth R. Wong, Kate Markham, Elizabeth Menendez, Kathy Kamath, Tony W. Liang, Jeanne Grace Flandez, Daniel R. Hostetter, James W. West, Chihunt Wong, Paul H. Bessette, Henry B. Lowman, Michael Krimm, Patrick S. Daugherty, Jason Gary Sagert
Publikováno v:
Science Translational Medicine. 5
Target-mediated toxicity constitutes a major limitation for the development of therapeutic antibodies. To redirect the activity of antibodies recognizing widely distributed targets to the site of disease, we have applied a prodrug strategy to create
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db22ff4ba0636787e1f4574421baf32
https://doi.org/10.1126/scitranslmed.3006682
https://doi.org/10.1126/scitranslmed.3006682
Autor:
David A. Chang-Yen, Yanting Zhang, Stephen James Moore, Paul M. Pellegrino, Andre' De Fusco, Marek Turewicz, H. Tom Soh, Joshua M. Kogot, Dimitra N. Stratis-Cullum, Paul Pagano, Nancy E. Stagliano
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 11, p e26925 (2011)
PLoS ONE, Vol 6, Iss 11, p e26925 (2011)
Bacterial surface peptide display has gained popularity as a method of affinity reagent generation for a wide variety of applications ranging from drug discovery to pathogen detection. In order to isolate the bacterial clones that express peptides wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577234c0962652b7dd2501bdb5f1012a
https://pubmed.ncbi.nlm.nih.gov/22140433
https://pubmed.ncbi.nlm.nih.gov/22140433