Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Stephen J.P. Pratt"'
Autor:
Patrick C. Bailey, Rachel M. Lee, Michele I. Vitolo, Stephen J.P. Pratt, Eleanor Ory, Kristi Chakrabarti, Cornell J. Lee, Keyata N. Thompson, Stuart S. Martin
Publikováno v:
iScience, Vol 8, Iss , Pp 29-39 (2018)
Summary: The mammosphere assay has become widely employed to quantify stem-like cells in a population. However, the problem is there is no standard protocol employed by the field. Cell seeding densities of 1,000 to 100,000 cells/mL have been reported
Externí odkaz:
https://doaj.org/article/5ecf840c180a4be4af26ec43d803e3e3
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease in which weakness, increased susceptibility to muscle injury, and inadequate repair appear to underlie the pathology. While most attention has focused within the muscle fiber, w
Externí odkaz:
https://doaj.org/article/f3e76d05787e47dea7aeedd38dd317e5
Autor:
Makenzy L. Mull, Stephen J.P. Pratt, Keyata N. Thompson, David A. Annis, Abanoub A. Gad, Rachel M. Lee, Katarina T. Chang, Megan B. Stemberger, Julia A. Ju, Darin E. Gilchrist, Liron Boyman, Michele I. Vitolo, W. Jonathan Lederer, Stuart S. Martin
Publikováno v:
bioRxiv
The tumor microenvironment and wound healing after injury, both contain extremely high concentrations of the extracellular signaling molecule, adenosine triphosphate (ATP) compared to normal tissue. P2Y2 receptor, an ATP-activated purinergic receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78aa45db9744bdc6e2ea3d69527d6092
https://doi.org/10.1101/2023.03.31.533191
https://doi.org/10.1101/2023.03.31.533191
Publikováno v:
Biophysical Reviews
Calcium is a versatile element that participates in cell signaling for a wide range of cell processes such as death, cell cycle, division, migration, invasion, metabolism, differentiation, autophagy, transcription, and others. Specificity of calcium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132b59aa295ade5fdc4f2413fc5b1e39
http://europepmc.org/articles/PMC7755621
http://europepmc.org/articles/PMC7755621
Autor:
Trevor J. Mathias, Julia A. Ju, Christopher M. Jewell, Rachel M. Lee, Stephen J.P. Pratt, Keyata Thompson, Michele Vitolo, Eleanor C Ory, Cornell J. Lee, Stuart S. Martin
Publikováno v:
Lab Chip
The technical challenges of imaging non-adherent tumor cells pose a critical barrier to understanding tumor cell responses to the non-adherent microenvironments of metastasis, like the bloodstream or lymphatics. In this study, we optimized a microflu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbac99f6896ff07b5c75bf1354cae443
https://doi.org/10.1039/d0lc00207k
https://doi.org/10.1039/d0lc00207k
Autor:
Ponvijay eKombairaju, Jaclyn P Kerr, Joseph A Roche, Stephen J.P Pratt, Richard M Lovering, Thomas E Sussan, Jung-Hyun eKim, Guoli eShi, Shyam eBiswal, Christopher William Ward
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Oxidative stress is a critical disease modifier in the muscular dystrophies. Recently, we discovered a pathway by which mechanical stretch activates NADPH Oxidase 2 (NoX2) dependent ROS generation (X-ROS). Our work in dystrophic skeletal muscle revea
Externí odkaz:
https://doaj.org/article/902b720b7a07474fb6003d5a3c426a46
Publikováno v:
Biotechniques
Isolated myofibers are commonly used to understand the function of skeletal muscle in vivo. This can involve single isolated myofibers obtained from dissection or from enzymatic dissociation. Isolation via dissection allows control of sarcomere lengt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bc816d337f88ffaa6992bc0aba3406
https://pubmed.ncbi.nlm.nih.gov/33000629
https://pubmed.ncbi.nlm.nih.gov/33000629
Autor:
Keyata Thompson, Cornell J. Lee, Patrick C. Bailey, Christopher M. Jewell, Stephen J.P. Pratt, Stuart S. Martin, Eleanor C Ory, Katarina T. Chang, Karen F. Underwood, Julia A. Ju, Trevor M. Mathias, Lekhana Bhandary, Michele Vitolo, Rebecca A. Whipple
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Mammosphere assays are widely used in vitro to identify prospective cancer-initiating stem cells that can propagate clonally to form spheres in free-floating conditions. However, the traditional mammosphere assay inevitably introduces cell aggregatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96357e3e766ff00904d97a1c53b57051
https://pubmed.ncbi.nlm.nih.gov/33547369
https://pubmed.ncbi.nlm.nih.gov/33547369
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1452, p 1452 (2020)
Cancers, Vol 12, Iss 1452, p 1452 (2020)
Mechanotransduction is the interpretation of physical cues by cells through mechanosensation mechanisms that elegantly translate mechanical stimuli into biochemical signaling pathways. While mechanical stress and their resulting cellular responses oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81bf1d12a61f3f7e33ccae39f764246
https://pubmed.ncbi.nlm.nih.gov/32503141
https://pubmed.ncbi.nlm.nih.gov/32503141
Autor:
Rachel M. Lee, Patrick C. Bailey, Keyata Thompson, Kristi R. Chakrabarti, Michele Vitolo, Eleanor C Ory, Cornell J. Lee, Stuart S. Martin, Stephen J.P. Pratt
Publikováno v:
iScience, Vol 8, Iss, Pp 29-39 (2018)
iScience
iScience
Summary The mammosphere assay has become widely employed to quantify stem-like cells in a population. However, the problem is there is no standard protocol employed by the field. Cell seeding densities of 1,000 to 100,000 cells/mL have been reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254e16999f8b735ab20852948b0cc030
https://doi.org/10.1016/j.isci.2018.08.015
https://doi.org/10.1016/j.isci.2018.08.015