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pro vyhledávání: '"Stephen J.E. Murphy"'
Autor:
Praveen Radhakrishnan, Laura Casals-Diaz, Moritz J. Strowitzki, Martin Schneider, Eric Brown, Cormac T. Taylor, Leila Smith, Bianca Crifo, Stephen J.E. Murphy, Martin Steinhoff, Ellen H. van den Bogaard, Raphael R. Fagundes, Doug N. Halligan, Hanna Niehues, Mario C. Manresa
Publikováno v:
Allergy, 74, 753-766
Allergy, 74(4), 753-766. Wiley-Blackwell
Allergy, 74, 4, pp. 753-766
Allergy, 74(4), 753-766. Wiley-Blackwell
Allergy, 74, 4, pp. 753-766
Background When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. The hypoxia‐inducible factor‐1α (HIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4f9ae7f987c73233c85b75f12db898
http://hdl.handle.net/2066/202595
http://hdl.handle.net/2066/202595
Publikováno v:
Seminars in Immunology. 28:469-477
Crosstalk between metabolic and immune pathways has recently become appreciated to be key to the regulation of host defence. The hypoxia-inducible factor (HIF) is a transcription factor which was initially described as a ubiquitous master regulator o