Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Stephen J. Szilvassy"'
Autor:
Meletios-Nikolaos Doulgkeroglou, Alessia Di Nubila, Bastian Niessing, Niels König, Robert H. Schmitt, Jackie Damen, Stephen J. Szilvassy, Wing Chang, Lynn Csontos, Sharon Louis, Patrick Kugelmeier, Vincent Ronfard, Yves Bayon, Dimitrios I. Zeugolis
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Although regenerative medicine products are at the forefront of scientific research, technological innovation, and clinical translation, their reproducibility and large-scale production are compromised by automation, monitoring, and standardization i
Externí odkaz:
https://doaj.org/article/3de3c8e6e64145348d519de5459ffc91
Autor:
Stewart C. Whitman, Debra L. Rateri, Stephen J. Szilvassy, Joseph A. Cornicelli, Alan Daugherty
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 8, Pp 1201-1208 (2002)
Class A scavenger receptors (SR-A) have been implicated in the atherogenic process, although there have been conflicting reports as to their specific effect on the development of lesions. In part, this discord may arise because of the variable contri
Externí odkaz:
https://doaj.org/article/e3f3bd25edec40b6bfae7769e79d17da
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 5, Pp 768-771 (2002)
Feeding interleukin-4 (IL-4) deficient C57BL/6 LDL receptor (LDLr)−/− mice a modified diet to investigate the role of this cytokine in cholesterol metabolism led to an unexpected phenotype. IL-4−/− → LDLr−/− mice had enlarged gallbladde
Externí odkaz:
https://doaj.org/article/b57ad7c916ea4b1c89702e5bb47bf217
Autor:
Wing Chang, Jaspreet Gill, Leon Lin, Albertus W. Wognum, Stephen J. Szilvassy, Allen C. Eaves, Sharon A. Louis, Marta A. Walasek
Publikováno v:
Blood. 138:4289-4289
The process of hemostasis and blood coagulation relies heavily on a sufficient supply of platelets (PLTs, also known as thrombocytes) within a person's bloodstream. Platelet transfusion is an effective treatment for thrombocytopenia-related diseases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc953cfc0c7247b199acb6e40adbc2d3
https://doi.org/10.1182/blood-2021-148715
https://doi.org/10.1182/blood-2021-148715
Autor:
Tim Le Fevre, Elaine Ang, Albertus W Wognum, Stephen J Szilvassy, Sharon A Louis, Allen C Eaves, Nooshin Tabatabaei-Zavareh
Publikováno v:
The Journal of Immunology. 206:26.03-26.03
Natural killer (NK) cells are critical effectors of innate immunity that secrete proinflammatory cytokines and kill tumor cells and virus-infected cells. The ability to expand human NK cells in culture provides a ready source of cells for disease mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9907e42b7c8d9b5011faf1d68d0cd78
https://doi.org/10.4049/jimmunol.206.supp.26.03
https://doi.org/10.4049/jimmunol.206.supp.26.03
Autor:
Sharon A. Louis, Marta A. Walasek, Jackie Damen, Stephen J. Szilvassy, Allen C. Eaves, Ali G. Turhan, Hanyang Lin, Albertus W. Wognum
Publikováno v:
Experimental Hematology. 90:52-64.e11
Research on chronic and acute myeloid leukemia (CML/AML) is focused on the development of novel therapeutic strategies to eliminate leukemic stem/progenitor cells that are responsible for drug resistance and disease relapse. Methods to culture hemato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9715a2db57cf3dffb09cdb00c36cf5c3
https://doi.org/10.1016/j.exphem.2020.08.004
https://doi.org/10.1016/j.exphem.2020.08.004
Autor:
Sharon A. Louis, Crystal Chau, Matthew Richardson, Stephen J. Szilvassy, Christian Barborini, Marta A. Walasek, Albertus W. Wognum, Allen C. Eaves, Terry Thomas
Publikováno v:
Blood. 134:1189-1189
Erythroid cells generated from human pluripotent stem cells (hPSCs) can potentially offer an unlimited and safe supply of red blood cells (RBCs) for transfusion. Human PSC-derived erythroid cells at various stages of differentiation can also be used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84bdf42ba4b1e66dcf377df719398ede
https://doi.org/10.1182/blood-2019-128830
https://doi.org/10.1182/blood-2019-128830
Autor:
Stephen J. Szilvassy, Jackie Damen, Leon Lin, Allen C. Eaves, Terry Thomas, Albertus W. Wognum
Publikováno v:
Experimental Hematology. 76:S75
Studies of hematopoietic stem and progenitor cells (HSPCs) in Acute and Chronic Myeloid Leukemia (AML and CML) are often hampered by limited access to patient samples and poor yield/viability of cryopreserved cells. We developed a culture system that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::decbdc5d7dce3d22da6fa63974d55b3b
https://doi.org/10.1016/j.exphem.2019.06.395
https://doi.org/10.1016/j.exphem.2019.06.395
Publikováno v:
Blood. 106:1479-1487
To test the hypothesis that aging has negative effects on stem-cell homing and engraftment, young or old C57BL/6 bone marrow (BM) cells were injected, using a limiting-dilution, competitive transplantation method, into old or young Ly5 congenic mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0363937bb96dbed640329e539056a0
https://doi.org/10.1182/blood-2004-11-4282
https://doi.org/10.1182/blood-2004-11-4282
Publikováno v:
Experimental Hematology. 32:60-67
Objective It is notable that there is significant inter-individual variability in humans and inter-strain variability in mice in the ability to mobilize hematopoietic stem and progenitor cells, suggesting that there is genetic regulation of mobilizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef5840450764bf14eb0a6399f096cea
https://doi.org/10.1016/j.exphem.2003.09.015
https://doi.org/10.1016/j.exphem.2003.09.015