Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stephen J. Rosenfeld"'
Publikováno v:
Research Ethics Review, Vol 19 (2023)
The current system of ethical oversight in the United States is based on Institutional Review Board (IRB) review. The system was established in response to well-known and egregious mistreatment of subjects in both biomedical and social and behavioral
Externí odkaz:
https://doaj.org/article/acf19524ca9741039979fd09c58d6899
Publikováno v:
Annals of Internal Medicine. 173:558-562
Evaluating the quality and effectiveness of the institutional review boards (IRBs) responsible for overseeing research involving human participants is critically important but perpetually challenging. Seemingly common-sense measures, such as the numb
Autor:
Stephen J. Rosenfeld
Publikováno v:
The Ochsner Journal
Background: Satisfactory measurements of the quality of institutional review board (IRB) reviews and services continue to be elusive. For evaluative purposes, the review process can be separated into two parts: the administrative functions that suppo
Autor:
Barbara E. Bierer, Holly Fernandez Lynch, Andrea Seykora, Carl H. Coleman, Stephen J. Rosenfeld
Publikováno v:
Ethicshuman researchReferences. 43(6)
Institutional review boards (IRBs) have been criticized for inconsistency and lack of transparency in decision-making, problems that undermine both trust in their ability to protect human research participants and respect for their decisions among re
Autor:
Stephen J. Rosenfeld
Publikováno v:
The Ochsner Journal
The well-worn adage “you can’t manage what you can’t measure” captures a particular view of management that has been reinforced by ideas such as continuous quality improvement. The idea that management means optimizing measurable outcomes mak
Autor:
Richard W. Childs, J Preuss, Sheila Phang, Engler H, Carlos Sánchez, Cynthia E. Dunbar, Michelle Plante, F van Rhee, Stephen J. Rosenfeld, Austin John Barrett
Publikováno v:
Bone Marrow Transplantation. 22:889-893
Nine of 56 (20% actuarial) patients receiving a T cell-depleted, HLA-identical sibling BMT for hematological malignancy developed hemorrhagic cystitis (HC) 15-368 days post BMT. Hematuria was severe and prolonged (median duration 18 days). In eight p
Autor:
Kristin Hansmann, McDonald K. Horne, Margaret E. Rick, Laurie P. McKeown, William A. Gahl, Kathryn E. Rosenfeld, Stephen J. Rosenfeld, Olga J. Wilson, Harvey R. Gralnick
Publikováno v:
American Journal of Hematology. 59:115-120
The Hermansky-Pudlak Syndrome (HPS) is an autosomal recessive inherited disorder characterized by oculocutaneous albinism, tissue accumulation of ceroid pigment, and a mild to moderate bleeding diathesis attributed to storage-pool deficient (SPD) pla
Autor:
Stephen J. Rosenfeld
Independent Institutional Review Boards (IRBs) are a product of the evolving research environment in the United States. They serve the need created by the migration of clinical research from the university hospital to the doctor's office, and they re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9c8219e0f6b3090eb57bb05a9883abd
https://doi.org/10.1016/b978-0-12-382167-6.00006-0
https://doi.org/10.1016/b978-0-12-382167-6.00006-0
Autor:
Paul S. Albert, Olivia T. Bartlett, Angela Bates, David A. Bluemke, Craig B. Borkowf, John T. Burklow, Susan Lowell Butler, Robert M. Califf, Leighton Chan, James J. Cimino, Melissa C. Colbert, Irene Dankwa-Mullan, Dennis O. Dixon, Ezekiel J. Emanuel, Thomas A. Fleisher, Bradley D. Freeman, Lawrence M. Friedman, William A. Gahl, Elaine K. Gallin, John I. Gallin, Lynn H. Gerber, Bruce Goldstein, Michael M. Gottesman, Christine Grady, P. Suzanne Hart, Clare Hastings, David K. Henderson, Nicholas C. Ide, Laura Lee Johnson, Jillian Kallman Price, Barbara I. Karp, Miriam Kelty, Harvey G. Klein, Bruce R. Korf, Rhonda G. Kost, Patricia A. Kvochak, Laura M. Lee, Juan J.L. Lertora, Nianjun Liu, Songtao Liu, Thomas C. Markello, Margaret A. Matula, Patrick McGarey, Patrick R. Murray, Charles Natanson, Robert B. Nussenblatt, Frederick P. Ognibene, Christopher O. Olopade, Olufunmilayo I. Olopade, Sope Olugbile, Vivian W. Pinn, Karen E. Pitt, Michael A. Proschan, Alan T. Remaley, Denise T. Resnik, Kyu Bak Louis Rhee, Stephen J. Rosenfeld, Pamela A. Shaw, Joanna H. Shih, Amy P.N. Skubitz, Marjorie Speers, Diane C. St. Germain, Catherine M. Stoney, Stephen E. Straus, Junfeng Sun, Nancy S. Sung, Tony Tse, Konstantina M. Vanevski, Alison Wichman, Rebecca J. Williams, Jennifer Yessis, Robert A. Yetter, Deborah A. Zarin, Kathryn C. Zoon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8257de7f0fd3693a57182f85c91b6fe
https://doi.org/10.1016/b978-0-12-382167-6.01002-x
https://doi.org/10.1016/b978-0-12-382167-6.01002-x
Publikováno v:
Human Gene Therapy. 5:1121-1129
Cystic fibrosis (CF) results from mutations of the CF transmembrane conductance regulator (CFTR) gene and the consequent defective regulation of cAMP-stimulated Cl- permeability across epithelial cell apical membranes. Given that in vitro transfer of