Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stephen J. Pratt"'
Autor:
Stephen J. Pratt, Eleanor C Ory, Erick O. Hernández-Ochoa, Joseph P. Stains, Martin F. Schneider, Patrick C. Bailey, Julia A. Ju, Keyata Thompson, Christopher W. Ward, Trevor J. Mathias, Katarina T. Chang, David A Annis, Michele Vitolo, Rachel M. Lee, Stuart S. Martin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance In breast cancer, the chronically stiffening mechanical microenvironment promotes tumor growth/invasion. However, the molecular details and integration of cancer mechanotransduction signaling pathways are not well understood. We find tha
Autor:
Stephen J. Pratt, Rainer Reuss
Publikováno v:
Journal of Stored Products Research. 40:233-239
Exposing insects to toxicants such as phosphine (PH3) in sealed chambers is a common procedure in fumigant efficacy testing. During long exposures, carbon dioxide (CO2) produced by metabolic processes of fed insects may accumulate in the vessel. As C
Autor:
Laura Meek, Hélène Marie, David Attwell, Gregory D. Longmore, Josef T. Kittler, Martha Betson, Stephen J. Pratt, Holly Epple, Sergey M. Troyanovsky, Vania M.M. Braga, Stephen J. Moss
Publikováno v:
Journal of Biological Chemistry. 278:1220-1228
Cell-cell adhesive events affect cell growth and fate decisions and provide spatial clues for cell polarity within tissues. The complete molecular determinants required for adhesive junction formation and their function are not completely understood.
Autor:
Stephen J. Pratt
Publikováno v:
Journal of Stored Products Research. 39:507-520
Previous studies of phosphine (PH 3 ) uptake by insects have concentrated on the process as a whole (“gross uptake”), without distinguishing between absorption of the gas and oxidation to non-volatile products. The lower gross uptake by phosphine
Publikováno v:
Journal of Asia-Pacific Entomology. 5:237-240
Toxicity of various essential oils and their volatile components against the red flour beetle, Tribolium castaneum (Herbst) was determined. The most potent fumigant toxicity was found in essential oil from rosemary (LD 50 = 7.8 μl/l air) followed by
Autor:
Alison Brownlie, Bernard Thisse, Leonard I. Zon, Adriana Donovan, Yi Zhou, Ruth B. Phillips, Michael O. Dorschner, Barry H. Paw, Stephen J. Pratt, Christine Thisse
Publikováno v:
Blood. 100:4655-4659
Iron is an essential nutrient required for the function of all cells, most notably for the production of hemoglobin in red blood cells. Defects in the mechanisms of iron absorption, storage, or utilization can lead to disorders of iron-limited erythr
Publikováno v:
Development. 128:2095-2106
Mammalian lung develops as an evagination of ventral gut endoderm into the underlying mesenchyme. Iterative epithelial branching, regulated by the surrounding mesenchyme, generates an elaborate network of airways from the initial lung bud. Fibroblast
Autor:
Alison Brownlie, Kristen J. Dorian, Stephen L. Johnson, Danielle V. Irvine, Eric C. Liao, Andrew C. Oates, Andrew F. Wilks, Stephen J. Pratt, John H. Postlethwait, Leonard I. Zon, Barry H. Paw
Publikováno v:
Blood. 94:2622-2636
Members of the JAK family of protein tyrosine kinase (PTK) proteins are required for the transmission of signals from a variety of cell surface receptors, particularly those of the cytokine receptor family. JAK function has been implicated in hematop
Autor:
Patrik Wollberg, Andrew C. Oates, Leonard I. Zon, Stephen L. Johnson, Robert K. Ho, Barry H. Paw, Stephen J. Pratt, John H. Postlethwait, Andrew F. Wilks
Publikováno v:
Developmental Dynamics. 215:352-370
Transcription factors of the STAT family are required for cellular responses to multiple signaling molecules. After ligand binding-induced activation of cognate receptors, STAT proteins are phosphorylated, hetero- or homodimerize, and translocate to
Autor:
Heather MacLennan, Margaret S. Thompson, Yasuyuki Kishimoto, David C. Beier, Kyu-Ho Lee, Steven L. Johnson, Mattias Hammerschmidt, Leonard I. Zon, John H. Postlethwaite, Stephen J. Pratt, Jennifer J. Marden, Stefan Schulte-Merker
Publikováno v:
Developmental Genetics. 23:97-103
The BMP family of polypeptide growth factors has been shown to play diverse roles in establishing embryonic patterning and tissue fates. We report the cloning of the zebrafish homologue of BMP-2, examine its expression during embryogenesis, and find