Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen J. McAndrew"'
Autor:
John K. Cini, Richard T. Kenney, Susan Dexter, Stephen J. McAndrew, Rukiye-Nazan Eraslan, Rich Brody, Darrel J. Rezac, Rebecca Boohaker, Suzanne E. Lapi, Pankaj Mohan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCytokines have been promising cancer immunotherapeutics for decades, yet only two are licensed to date. Interleukin-12 (IL-12) is a potent regulator of cell-mediated immunity that activates NK cells and interferon-γ (IFNγ) production. It
Externí odkaz:
https://doaj.org/article/438bbbcb4fa04e72a0a4640f320246d0
Autor:
John K. Cini, Susan Dexter, Darrel J. Rezac, Stephen J. McAndrew, Gael Hedou, Rich Brody, Rukiye-Nazan Eraslan, Richard T. Kenney, Pankaj Mohan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe potential synergy between interleukin-12 (IL-12) and IL-15 holds promise for more effective solid tumor immunotherapy. Nevertheless, previous clinical trials involving therapeutic cytokines have encountered obstacles such as short pharm
Externí odkaz:
https://doaj.org/article/ec5b713791af4cd19df56d27a6cab5cc
Autor:
John K. Cini, Stephen J. McAndrew, Nick Evans, Lucie Janeckova, Maryam Ahmadi, Rukiye-Nazan Eraslan, Miglena G. Prabagar, Susan Dexter, Richard T. Kenney
Publikováno v:
Cancer Research. 82:4229-4229
Combination approaches using stimulatory cytokines, checkpoint inhibitors, chemotherapy and/or radiation therapy are known to improve overall survival of cancer patients. Recombinant interleukins (IL) have had limited clinical success due to short ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61350d47d043e158ac403c2a20145347
https://doi.org/10.1158/1538-7445.am2022-4229
https://doi.org/10.1158/1538-7445.am2022-4229
Autor:
Luis Pasamontes, Lorraine Tomchak, Stephen J. Mcandrew, Denis Hug, Karin Becker, Kramer Richard Allen, Markus Hümbelin
Publikováno v:
Molecular and Biochemical Parasitology. 60:327-331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2785d86aa6e01bdcc338c75eb13658
https://doi.org/10.1016/0166-6851(93)90144-m
https://doi.org/10.1016/0166-6851(93)90144-m
Autor:
Lawrence E. Hightower, Joseph P. Brown, Ivone M. Takenaka, Sau-Mei Leung, Stephen J. McAndrew
Publikováno v:
The Journal of biological chemistry. 270(34)
A 15-mer phage display random peptide library was screened with purified bovine Hsc70, and nucleotide sequence analysis of the selected clones showed a large enrichment for peptides containing basic sequences with at least KK, KR, or RR. Binding affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a193f742490a64a65b5785bf3d0ff5
https://pubmed.ncbi.nlm.nih.gov/7649995
https://pubmed.ncbi.nlm.nih.gov/7649995
Autor:
Peter T. Lomedico, Stephen J. Mcandrew
Publikováno v:
Nature. 299(5880)
The functional assay of a eukaryotic mRNA, into which additional AUG codons have been introduced by in vitro mutagenesis, shows that a translational initiation site need not necessarily be the nearest AUG codon to the 5' end of a mRNA. Hence, the seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b0f1e7c393617d704e1bde3b7ca257
https://pubmed.ncbi.nlm.nih.gov/6955600
https://pubmed.ncbi.nlm.nih.gov/6955600
Autor:
Juan Carlos Lacal, Vicente Notario, Shigeko Yamazaki, Hsiang-Fu Kung, Eugenio Santos, Stephen J. Mcandrew, Mariano Barbacid, Robert M. Crowl, Craig Seamans
Publikováno v:
Scopus-Elsevier
The H-ras gene of the BALB murine sarcoma virus (BALB-MSV) was placed under the transcriptional control of the tightly regulated PL promoter of bacteriophage lambda in the expression vectors pEV-vrf-1 and pRC23. Upon derepression of the PL promoter,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f781c5b8f519b973bec88df1349b104
http://www.scopus.com/inward/record.url?eid=2-s2.0-0021231311&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0021231311&partnerID=MN8TOARS
Publikováno v:
Gene. 45:117
We have constructed a set of expression vectors which contain synthetic DNA sequences comprising a computer-generated model ribosomal binding site located downstream from the tightly regulated phage λ pL promoter. These vectors have been used in sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db10f87cdfd4a98997e9f5fcf039d02
https://doi.org/10.1016/0378-1119(86)90140-x
https://doi.org/10.1016/0378-1119(86)90140-x