Výsledky vyhledávání - "Stephen J. Marsh"

Akademický článek

Functional significance of M-type potassium channels in nociceptive cutaneous sensory endings

Autor: Gayle M. Passmore, Joanne M. Reilly, Matthew eThakur, Vanessa N. Keasberry, Stephen J. Marsh, Anthony H. Dickenson, David A. Brown

Publikováno v: Frontiers in Molecular Neuroscience, Vol 5 (2012)

M-channels carry slowly activating potassium currents that regulate excitability in a variety of central and peripheral neurons. Functional M-channels and their Kv7 channel correlates are expressed throughout the somatosensory nervous system where th

Externí odkaz: https://doaj.org/article/4c5b9aad46da47d9bc568d7c1570948a

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Coupling of m2 and m4 muscarinic acetylcholine receptor subtypes to Ca 2+ -dependent K + channels in transformed NL308 neuroblastoma x fibroblast hybrid cells

Autor: Stephen J. Marsh, David A. Brown, Mami Noda, Shigeru Yokoyama, Haruhiro Higashida, Kazuhiko Fukuda, Naoto Hoshi, Jon Robbins, Morio Katayama, Nobuto Ishizaka

Publikováno v: Proceedings of the Royal Society of London. Series B: Biological Sciences. 251:215-224

Muscarinic acetylcholine receptor (mAChR) subtype (m1--m4)-specific cDNAs were transfected into NL308 neuroblastoma-fibroblast hybrid cells and clones expressing each of the individual mAChR subtypes m1, m2, m3 and m4 obtained. Acetylcholine increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de1feece4042dfcc16db5a3fbab8254
https://doi.org/10.1098/rspb.1993.0032

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Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition

Autor: David A, Brown, Simon A, Hughes, Stephen J, Marsh, Andrew, Tinker

Publikováno v: The Journal of physiology. 582(Pt 3)

M-channels are voltage-gated K+ channels that regulate the excitability of many neurons. They are composed of Kv7 (KCNQ) family subunits, usually Kv7.2 + Kv7.3. Native M-channels and expressed Kv7.2 + 7.3 channels are inhibited by stimulating G(q/11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f54401ecfa16d87613563d9030e95fd
https://pubmed.ncbi.nlm.nih.gov/17395626

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Probing the regulation of M (Kv7) potassium channels in intact neurons with membrane-targeted peptides

Autor: Jon Robbins, David A. Brown, Stephen J. Marsh

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(30)

M-type (Kv7) potassium channels are closed by Gq/11 G-protein-coupled receptors. Several membrane- or channel-associated molecules have been suggested to contribute to this effect, including depletion of phosphatidylinositol-4,5-bisphosphate (PIP2) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b338d1875b8a5d4effb159956636b2a
https://pubmed.ncbi.nlm.nih.gov/17058328

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Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors

Autor: Alexander K, Filippov, Jose M, Fernández-Fernández, Stephen J, Marsh, Joseph, Simon, Eric A, Barnard, David A, Brown

Publikováno v: Molecular pharmacology. 66(3)

Neuronal signaling by G protein-coupled P2Y nucleotide receptors is not well characterized. We studied here the coupling of different molecularly defined P2Y receptors to neuronal G protein-gated inward rectifier K(+) (GIRK) channels. Individual P2Y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aef2ddca2ecb1bf06666924b496b156a
https://pubmed.ncbi.nlm.nih.gov/15322238

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Reply [to 'Comment on ‘Negatively charged precipitation in a New Mexico thunderstorm’ by Thomas C. Marshall and Stephen J. Marsh and ‘Charged precipitation measurements before the first lightning flash in a thunderstorm’ by Stephen J. Marsh and Thomas C. Marshall']

Autor: Stephen J. Marsh, Thomas C. Marshall

Publikováno v: Journal of Geophysical Research. 100:16869

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e19a3a5a944430209d635e10258168a
https://doi.org/10.1029/95jd01366

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Charged precipitation measurements before the first lightning flash in a thunderstorm

Autor: Stephen J. Marsh, Thomas C. Marshall

Publikováno v: Journal of Geophysical Research. 98:16605

On August 15, 1984, we made balloon measurements of the electric field and of the charge and vertical velocity of precipitation particles in a thunderstorm over Langmuir Laboratory. Substantial quantities of positively charged precipitation, comprisi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9beaba6faee192860e403d7c8687394b
https://doi.org/10.1029/93jd00419

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4-Aminopyridine and dendrotoxin induce repetitive firing in rat visceral sensory neurones by blocking a slowly inactivating outward current

Autor: C. E. Stansfeld, J.V. Halliwell, Stephen J. Marsh, D.A. Brown

Publikováno v: Neuroscience letters. 64(3)

In a subpopulation of rat visceral afferent neurones we have identified a potassium (K) current which is novel to mammalian neurones. It activates rapidly at potentials positive to - 70 mV but shows only slow and incomplete inactivation and is inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6bde0eba71892c9c0cc10755601a11
https://pubmed.ncbi.nlm.nih.gov/2421213

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