Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stephen J. Libertini"'
Autor:
Alexander J. Platero, Alan P. Lombard, Maria Mudryj, Paramita M. Ghosh, Ai Hong Ma, Stephen J. Libertini, Kristine S. Nishida, Chong-Xian Pan, Kimberley Katleba, Han Bit Baek, Maria Malvina Tsamouri
Publikováno v:
Cancer Lett
Bladder cancer (BlCa) exhibits a gender disparity where men are three times more likely to develop the malignancy than women suggesting a role for the androgen receptor (AR). Here we report that BlCa cells express low molecular weight (LMW) AR isofor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df581cc7afca6041c7c65a9f5c7d94fb
https://escholarship.org/uc/item/5rn509g0
https://escholarship.org/uc/item/5rn509g0
Autor:
Aleida Fernandez-Rubio, Regina F Gandour-Edwards, Robert H. Weiss, Han Bit Baek, Ruth Louise Vinall, Hiromi I. Wettersten, Kristine S. Nishida, Alan P. Lombard, Stephen J. Libertini, Paramita M. Ghosh, Yosef Landesman, Rachel M. Nakagawa, Kathleen D. Vidallo, Maria Mudryj, Salma Siddiqui
Publikováno v:
Oncotarget, vol 9, iss 77
Oncotarget
Oncotarget
Treatment options for high grade urothelial cancers are limited and have remained largely unchanged for several decades. Selinexor (KPT-330), a first in class small molecule that inhibits the nuclear export protein XPO1, has shown efficacy as a singl
Autor:
Stephen J. Libertini, Kristin A Olson, John Douglas Mcpherson, Karen Matsukuma, Alexander Ladenheim, Alae Yaseen
Publikováno v:
Pathology - Research and Practice. 220:153406
Gut-associated lymphoid tissue (GALT) carcinoma is a colorectal neoplasm characterized by cystically dilated neoplastic glands that extend into prominent, well-circumscribed submucosal lymphoid tissue. Although often subtle, lamina propria between an
Autor:
Kathleen D. Vidallo, Rebecca M. Lim, Nicole Costanzo, Alan P. Lombard, Maria Mudryj, Benjamin A. Mooso, Paramita M. Ghosh, Stephen J. Libertini, Rachel M. Nakagawa
Publikováno v:
Molecular Carcinogenesis. 55:757-767
Urothelial cell carcinoma of the bladder (UCCB) is the most common form of bladder cancer and it is estimated that ~15,000 people in the United States succumbed to this disease in 2013. Bladder cancer treatment options are limited and research to und
Autor:
Tilak Koilvaram, Honglin Chen, Michael D. George, Stephen J. Libertini, Maria Mudryj, Bushra al-Bataina, Allen C. Gao
Publikováno v:
The Prostate. 72:649-660
BACKGROUND The E2F/RB pathway is frequently disrupted in multiple human cancers. E2F3 levels are elevated in prostate tumors and E2F3 overexpression independently predicts clinical outcome. The goals of this study were to identify direct transcriptio
Autor:
Honglin Chen, Hsing Jien Kung, Satya Dandekar, Michael D. George, Maria Mudryj, Paramita M. Ghosh, Clifford G. Tepper, Bushra al-Bataina, Stephen J. Libertini
Publikováno v:
Endocrine-Related Cancer. 17:857-873
Prostate carcinoma (CaP) is a heterogeneous multifocal disease where gene expression and regulation are altered not only with disease progression but also between metastatic lesions. The androgen receptor (AR) regulates the growth of metastatic CaPs;
Autor:
Maria Mudryj, Hsing Jien Kung, Paramita M. Ghosh, Stephen J. Libertini, Yu Wang, Honglin Chen
Publikováno v:
Journal of Biological Chemistry. 285:2368-2374
Androgen ablation therapy is effective in treating androgen-dependent prostate tumors; however, tumors that can proliferate in castrate levels of androgen eventually arise. We previously reported that in CWR22Rv1 (Rv1) cells, the protease calpain 2 c
Autor:
Alan P. Lombard, Alexander J. Platero, Stephen J. Libertini, Maria Mudryj, Kathleen D. Vidallo, Rebecca M. Lim, Rachel M. Nakagawa
Publikováno v:
Oncology reports. 34(3)
Dicer expression is frequently altered in cancer and affects a wide array of cellular functions acting as an oncogene or tumor suppressor in varying contexts. It has been shown that Dicer expression is also deregulated in urothelial cell carcinoma of
Autor:
Alan P, Lombard, Benjamin A, Mooso, Stephen J, Libertini, Rebecca M, Lim, Rachel M, Nakagawa, Kathleen D, Vidallo, Nicole C, Costanzo, Paramita M, Ghosh, Maria, Mudryj
Publikováno v:
Molecular carcinogenesis. 55(5)
Urothelial cell carcinoma of the bladder (UCCB) is the most common form of bladder cancer and it is estimated that ~15,000 people in the United States succumbed to this disease in 2013. Bladder cancer treatment options are limited and research to und
Autor:
Moraima Guadalupe, David M. Asmuth, Clifford G. Tepper, Stephen J. Libertini, Maria Mudryj, Ying Lu
Publikováno v:
The Prostate. 66:70-81
INTRODUCTION AND OBJECTIVES To investigate the role of E2F/RB in androgen independent proliferation, differentiation, and sensitivity to apoptotic stimuli of LNCaP prostate cancer cells. METHODS The effects of E2F1 overexpression on androgen independ