Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stephen J. Howard"'
Publikováno v:
Health education research. 33(5)
Advertisements are persuasive texts designed to communicate ideas explicitly and implicitly through visual grammar. Counter-advertisements allow students to engage with advertising texts as creators rather than consumers and challenge media messages.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4761c01047550aa5cfaa65cb10db2ed8
https://pubmed.ncbi.nlm.nih.gov/30137323
https://pubmed.ncbi.nlm.nih.gov/30137323
Autor:
Hari Krishna Santhapuram, Stephen J. Howard, Le-Cun Xu, Christopher P. Leamon, Elaine Westrick, P. Ron Ellis, Alicia Bloomfield, Iontcho Radoslavov Vlahov, Yingjuan Lu, Philip S. Low, Patrick J. Klein
Publikováno v:
The AAPS Journal. 11:628-638
Cancer vaccine/immunotherapy rarely involves systemic administration of an immunogenic compound to an actively immunized host. We have developed such a strategy that utilizes folate to deliver antigenic haptens [e.g., fluorescein (FITC) and dinitroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9e66e880625c9f2b94c67d990b68e2
https://doi.org/10.1208/s12248-009-9139-7
https://doi.org/10.1208/s12248-009-9139-7
Autor:
Hari Krishna Santhapuram, Elaine Westrick, Iontcho Radoslavov Vlahov, Christopher P. Leamon, Joseph A. Reddy, Fei You, Paul J. Kleindl, Stephen J. Howard, Yu Wang
Publikováno v:
The Journal of Organic Chemistry. 72:5968-5972
We describe the development of methodology which allows for the introduction of a second disulfide bond into a molecular framework with a pre-existing disulfide linker system. Compounds which contain an S-9-fluorenylmethyl-protected thiol and an addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d2ceb949f7b674076a79050dd2ebd0
https://doi.org/10.1021/jo070411z
https://doi.org/10.1021/jo070411z
Autor:
Francis F.Y. Lee, Fei You, Iontcho Radoslavov Vlahov, Stephen J. Howard, Paul J. Kleindl, Hari Krishna Santhapuram, Yu Wang, Gregory D. Vite, Christopher P. Leamon, Soong-Hoon Kim
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(15)
Efficient regioselective syntheses of conjugates of folic acid and cytotoxic agents derived from natural epothilones are described. These folate receptor (FR) targeting compounds are water soluble and incorporate a hydrophilic peptide-based spacer un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3a073ce6aa53e33ccca9a92b340779
https://pubmed.ncbi.nlm.nih.gov/20594844
https://pubmed.ncbi.nlm.nih.gov/20594844
Autor:
Marilynn Vetzel, Iontcho Radoslavov Vlahov, Ravi V. J. Chari, Hari Krishna Santhapuram, Victor S. Goldmacher, Stephen J. Howard, Michael L. Miller, Christopher Paul Leamon, Joseph A. Reddy, Elaine Westrick
Publikováno v:
Cancer research. 67(13)
EC131, a new folate receptor (FR)–targeted drug conjugate, was prepared by covalently attaching the vitamin folic acid (FA) to a potent microtubule-inhibiting agent, maytansinoid DM1, via an intramolecular disulfide bond. When tested on cells in cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900466a9721e554b51b83a056645f6ae
https://pubmed.ncbi.nlm.nih.gov/17616697
https://pubmed.ncbi.nlm.nih.gov/17616697
Autor:
Hari Krishna Santhapuram, Iontcho Radoslavov Vlahov, Paul J. Kleindl, Stephen J. Howard, Christopher P. Leamon, Katheryn Marie Stanford
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(19)
An efficient synthesis of the folate receptor (FR) targeting conjugate EC145 is described. EC145 is a water soluble derivative of the vitamin folic acid and the potent cytotoxic agent, desacetylvinblastine monohydrazide. Both molecules are connected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0692bc273d54ecd8f9b0e02d3a233d20
https://pubmed.ncbi.nlm.nih.gov/16870437
https://pubmed.ncbi.nlm.nih.gov/16870437
Autor:
Hari Krishna Santhapuram, Stephen J. Howard, Iontcho Radoslavov Vlahov, Joseph A. Reddy, Elaine Westrick, Christopher P. Leamon
Publikováno v:
Cancer chemotherapy and pharmacology. 58(2)
Purpose: Folate receptor (FR) targeted drug conjugates were prepared by covalently attaching the vitamin folate, to the potent anticancer drug, mitomycin C (MMC). One such conjugate, called EC72, was synthesized with an intramolecular disulfide bond,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b500ea5ce4224142ead78d532661026
https://pubmed.ncbi.nlm.nih.gov/16331500
https://pubmed.ncbi.nlm.nih.gov/16331500
Autor:
Stephen J. Howard, Pierre Wils, Hans Hofland, Christopher P. Leamon, Chandrika Abburi, Iontcho Radoslavov Vlahov, Joseph A. Reddy
Publikováno v:
Gene therapy. 9(22)
A folate-targeted, cationic lipid based transfection complex was developed and found to specifically transfect folate receptor-expressing cells and tumors. These liposomal vectors were comprised of protamine-condensed plasmid DNA, a mixture of cation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a025ba27f4c06946a0ed46d09c1dc8
https://pubmed.ncbi.nlm.nih.gov/12407426
https://pubmed.ncbi.nlm.nih.gov/12407426
Publikováno v:
Analytical Biochemistry. 154:110-117
The possibility of producing biospecific affinity ligands for separating cells in two polymer aqueous phase systems on the basis of cell surface antigens was investigated. Rabbit anti-human erythrocyte IgG was reacted with cyanuric chloride-activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfae63103290dcc3449b46594b09e40f
https://doi.org/10.1016/0003-2697(86)90503-8
https://doi.org/10.1016/0003-2697(86)90503-8