Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Stephen J. Getting"'
Publikováno v:
Cells, Vol 11, Iss 1, p 132 (2021)
Increased osteoclast (OC) differentiation and activity is the critical event that results in bone loss and joint destruction in common pathological bone conditions, such as osteoporosis and rheumatoid arthritis (RA). RANKL and its decoy receptor, ost
Externí odkaz:
https://doaj.org/article/3717b258980941ad9d05132c01709d1b
Publikováno v:
The Scientific World Journal, Vol 10, Pp 434-456 (2010)
Saliva has been described as the mirror of the body. In a world of soaring healthcare costs and an environment where rapid diagnosis may be critical to a positive patient outcome, saliva is emerging as a viable alternative to blood sampling. In this
Externí odkaz:
https://doaj.org/article/29d79a0f717c4e5e9ad2acfa48b91ea5
Autor:
Stephen J. Getting
Publikováno v:
The Scientific World Journal, Vol 7, Pp 1463-1464 (2007)
Externí odkaz:
https://doaj.org/article/3acfae814e96411bbe6aa1cc9195722d
Publikováno v:
The FEBS Journal. 289:1801-1822
Alzheimer's disease and dementia are among the most significant current healthcare challenges given the rapidly growing elderly population, and the almost total lack of effective therapeutic interventions. Alzheimer's disease pathology has long been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888e1042a62c5c29e8c1c9918704d689
https://doi.org/10.1111/febs.15861
https://doi.org/10.1111/febs.15861
Autor:
Mc Trotta, Paolo Grieco, Francesco Testa, Rosa Maisto, Enrico Maria Surace, Francesca Simonelli, Francesco Merlino, Settimio Rossi, Michele D'Amico, Mauro Perretti, C Di Filippo, Stephen J. Getting, Magdalena Kaneva, Francesca Ferraraccio, Carlo Gesualdo
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Mediators of Inflammation
Mediators of Inflammation
We hypothesize that melanocortin receptors (MC) could activate tissue protective circuit in a model of streptozotocin- (STZ-) induced diabetic retinopathy (DR) in mice. At 12-16 weeks after diabetes induction, fluorescein angiography (FAG) revealed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62628b240050ba0d02df73461696769
https://doaj.org/article/865ba96633c7475aa3afebfe07231666
https://doaj.org/article/865ba96633c7475aa3afebfe07231666
Autor:
Stephen J. Getting, Simon McArthur, Bradley T. Elliott, Edward S. Wickstead, Christopher S. Biggs
Neuroinflammation driven primarily by microglia directly contributes to neuronal death in many neurodegenerative diseases. Classical anti-inflammatory approaches aim to suppress pro-inflammatory mediator production, but exploitation of inflammatory r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fead3db98dfda3756711ce491a289da
https://doi.org/10.1101/2020.07.09.195198
https://doi.org/10.1101/2020.07.09.195198
Autor:
Roberta E Manuel, Simon McArthur, Christopher S. Biggs, Stephen J. Getting, Husnain A Karim, Edward S. Wickstead
Background and PurposeMicroglial inflammatory activity is thought to be a major contributor to the pathology of neurodegenerative conditions such as Alzheimer’s disease (AD), and strategies to restrain their behaviour are under active investigation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126d1d7bd4d3f92dae7512fed717935f
https://doi.org/10.1101/2020.02.13.947051
https://doi.org/10.1101/2020.02.13.947051
Autor:
Husnain A Karim, Stephen J. Getting, Christopher S. Biggs, Simon McArthur, Edward S. Wickstead, Roberta E Manuel
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Microglial inflammatory activity is thought to be a major contributor to the pathology of neurodegenerative conditions such as Alzheimer’s disease (AD), and strategies to restrain their behaviour are under active investigation. Classically, anti-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6bfb5a1c854b256a04c85dfd69786a
Autor:
Mark J.P. Kerrigan, Francesco Merlino, Paolo Grieco, V.C. Can, Stephen J. Getting, Clara De Pascale, Magdalena Kaneva, Ian C. Locke
Publikováno v:
European journal of pharmacology. 872
Human melanocortin MC1 and MC3 receptors expressed on C-20/A4 chondrocytes exhibit chondroprotective and anti-inflammatory effects when activated by melanocortin peptides. Nearly 9 million people in the UK suffer from osteoarthritis, and bacterial in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cefa7cfabc6617ac73dd63572cc6bf
https://pubmed.ncbi.nlm.nih.gov/32004526
https://pubmed.ncbi.nlm.nih.gov/32004526
Extracellular vesicles (EVs) are a heterogenous population of vesicles originate from cells. EVs are found in different biofluids and carry different macromolecules, including proteins, lipids, and nucleic acids, providing a snap shot of the parental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d678af8c393bcf879213fd7028a949dd
https://nrl.northumbria.ac.uk/id/eprint/35188/1/Momen_Heravi_et_al_Uwe.pdf
https://nrl.northumbria.ac.uk/id/eprint/35188/1/Momen_Heravi_et_al_Uwe.pdf