Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Stephen J. Daly"'
Publikováno v:
Spectroscopy Letters. 38:229-245
Aflatoxin B1 (AFB1) is a highly toxic secondary metabolite of the fungal species Aspergillus flavus and Aspergillus parasiticus produced under certain environmental conditions. The gene encoding an AFB1‐specific single‐chain fragment variable (sc
Autor:
Bruce R. Westley, Brendan Drumm, Richard O'Kennedy, Paul P. Dillon, Felicity E. B. May, Stephen J. Daly, Marguerite Clyne
Publikováno v:
Proceedings of the National Academy of Sciences. 101:7409-7414
Why Helicobacter pylori colonizes only gastric tissue is unknown. It is found on gastric mucus-secreting cells and in the overlying gastric mucus but not deep in gastric glands. This localization mirrors the expression of trefoil factor 1, TFF1. We h
Publikováno v:
International Journal of Environmental Analytical Chemistry. 83:525-543
The interaction between antibody and antigen is characterised by relatively high affinity and specificity, making this type of reaction a prime candidate for use as an analytical tool. The interaction may be combined with biosensors in the production
Autor:
Paul P. Dillon, Anthony J. Killard, Richard O'Kennedy, Bernadette M. Manning, Stephen J. Daly
Publikováno v:
Journal of Immunological Methods. 276:151-161
A recombinant single-chain variable fragment (scFv) antibody to morphine-3-glucuronide (M3G) was produced using genetic material obtained from the spleen cells of mice immunised with a morphine-3-glucuronide-bovine serum albumin (M3G-BSA) conjugate.
Publikováno v:
Biosensors and Bioelectronics. 18:217-227
Polyclonal antibodies were produced for the development of competitive ELISA's and surface plasmon resonance (SPR)-based BIAcore inhibition assays for the detection of morphine-3-glucuronide (M3G, the main metabolite of heroin and morphine). A conjug
Publikováno v:
Analytical Letters. 36:511-537
Miniaturized screening devices (MSDs) are an emerging technology with a variety of possible applications e.g., detection of diseases, analysis of antibiotics or illicit drugs. MSDs include a variety of different working principles and components. The
Autor:
Paul P. Dillon, E.E.M.G. Loomans, John G. Browne, Bernadette M. Manning, Stephen J. Daly, Richard O'Kennedy, Aart van Amerongen
Publikováno v:
Food and Agricultural Immunology, 15(3-4), 225-234
Food and Agricultural Immunology 15 (2003) 3-4
Food and Agricultural Immunology 15 (2003) 3-4
Public concern surrounding antibiotic contamination in food and food products has made it imperative to develop analytical methods for their detection. Polyclonal antibodies were used in the development of a surface plasmon resonance (SPR)-based inhi
Autor:
Anthony J. Killard, Bernadette M. Manning, Stephen J. Daly, Paul P. Dillon, Lynsey Dunne, Richard O'Kennedy
Publikováno v:
Food and Agricultural Immunology. 14:255-274
The production and characterization of recombinant antibodies to aflatoxin B 1 (AFB 1 ), a potent mycotoxin and carcinogen is described. The antibody fragments produced were then applied for use in a surface plasmon resonance-based biosensor (BIAcore
Autor:
Jane Fitzpatrick, Lynsey Dunne, Paul P. Dillon, Joanne Brennan, Stephen J. Daly, Richard O'Kennedy
Publikováno v:
Analytical Letters. 34:1799-1827
Polyclonal and monoclonal antibody molecules have had a significant impact in analytical detection systems throughout the last few decades. Recently, the emergence of recombinant antibody technology is also playing a part in diagnostic applications.
Autor:
Bernadette M. Manning, Stephen J. Daly, John G. Quinn, Kenny Lang, Heather A. Lee, Richard O'Kennedy, Brian Fitzpatrick, Paul P. Dillon, Pritesh Patel, Marcos J. C. Alcocer, Michael R. A. Morgan
Publikováno v:
Biosensors and Bioelectronics. 14:587-595
The regeneration of antibody-binding surfaces is of major importance for re-usable sensor formats such as required for direct ‘real-time’ biosensing technologies and is often difficult to achieve. Antibodies commonly bind the antigen with high av