Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Stephen J. Barigye"'
Autor:
Kevin Castillo-Mendieta, Guillermin Agüero-Chapin, Edgar A. Marquez, Yunierkis Perez-Castillo, Stephen J. Barigye, Nelson Santiago Vispo, Cesar R. García-Jacas, Yovani Marrero-Ponce
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-18 (2024)
Abstract Peptides are promising drug development frameworks that have been hindered by intrinsic undesired properties including hemolytic activity. We aim to get a better insight into the chemical space of hemolytic peptides using a novel approach ba
Externí odkaz:
https://doaj.org/article/4cd69d0a7ddc43d3a8057d947214606c
Autor:
Laureano E. Carpio, Marta Olivares, Alfonso Benítez-Paez, Eva Serrano-Candelas, Stephen J. Barigye, Yolanda Sanz, Rafael Gozalbes
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5744 (2024)
The role of the gut microbiota and its interplay with host metabolic health, particularly in the context of type 2 diabetes mellitus (T2DM) management, is garnering increasing attention. Dipeptidyl peptidase 4 (DPP4) inhibitors, commonly known as gli
Externí odkaz:
https://doaj.org/article/4a026f65921840ea9ead33f0fa477c8c
Autor:
Soroush Moasses Ghafary, Paula M. Soriano-Teruel, Shima Lotfollahzadeh, Mónica Sancho, Eva Serrano-Candelas, Fatemeh Karami, Stephen J. Barigye, Iván Fernández-Pérez, Rafael Gozalbes, Maryam Nikkhah, Mar Orzáez, Saman Hosseinkhani
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1651 (2022)
Inflammasomes are multiprotein complexes that represent critical elements of the inflammatory response. The dysregulation of the best-characterized complex, the NLRP3 inflammasome, has been linked to the pathogenesis of diseases such as multiple scle
Externí odkaz:
https://doaj.org/article/e6a1c1142a1f4ec899beb5196c854715
Autor:
José R. Valdés-Martiní, Yovani Marrero-Ponce, César R. García-Jacas, Karina Martinez-Mayorga, Stephen J. Barigye, Yasser Silveira Vaz d‘Almeida, Hai Pham-The, Facundo Pérez-Giménez, Carlos A. Morell
Publikováno v:
Journal of Cheminformatics, Vol 9, Iss 1, Pp 1-26 (2017)
Abstract Background In previous reports, Marrero-Ponce et al. proposed algebraic formalisms for characterizing topological (2D) and chiral (2.5D) molecular features through atom- and bond-based ToMoCoMD-CARDD (acronym for Topological Molecular Comput
Externí odkaz:
https://doaj.org/article/f67517b919f8485d973e753d195433dd
Autor:
Elizabeth Goya Jorge, Anita Maria Rayar, Stephen J. Barigye, María Elisa Jorge Rodríguez, Maité Sylla-Iyarreta Veitía
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 6, p 881 (2016)
A quantitative structure-activity relationship (QSAR) study of the 2,2-diphenyl-l-picrylhydrazyl (DPPH•) radical scavenging ability of 1373 chemical compounds, using DRAGON molecular descriptors (MD) and the neural network technique, a technique ba
Externí odkaz:
https://doaj.org/article/39d0110cdc4c4f1eb67d7acc4835d3d9
Autor:
Oscar Martínez-Santiago, Yovani Marrero-Ponce, Stephen J. Barigye, Huong Le Thi Thu, F. Javier Torres, Cesar H. Zambrano, Jorge L. Muñiz Olite, Maykel Cruz-Monteagudo, Ricardo Vivas-Reyes, Liliana Vázquez Infante, Luis M. Artiles Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 6, p 812 (2016)
This report examines the interpretation of the Graph Derivative Indices (GDIs) from three different perspectives (i.e., in structural, steric and electronic terms). It is found that the individual vertex frequencies may be expressed in terms of the g
Externí odkaz:
https://doaj.org/article/4b2d2917c78743e2b42b015aed912081
Exploring proteasome inhibition using atomic weighted vector indices and machine learning approaches
Autor:
Yoan Martínez-López, Juan A. Castillo-Garit, Gerardo M. Casanola-Martin, Bakhtiyor Rasulev, Ansel Y. Rodríguez-Gonzalez, Oscar Martínez-Santiago, Stephen J. Barigye
Publikováno v:
Molecular Diversity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a71bed3ffc5ccd3c6e5d3fcd4334b5
https://doi.org/10.1007/s11030-023-10638-2
https://doi.org/10.1007/s11030-023-10638-2
Autor:
Kevin Castillo-Mendieta, Guillermin Agüero-Chapin, Nelson Santiago Vispo, Edgar A. Márquez, Yunierkis Perez-Castillo, Stephen J. Barigye, Yovani Marrero-Ponce
Peptides are promising drug development frameworks thanks to their high target selectivity, tolerability and relatively low production cost. However, despite the fact that several thousand potentially therapeutic peptides reported, only sixty have ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c4f0efe4b4dc1bee56147b72b10f38
Publikováno v:
Chemometrics and Cheminformatics in Aquatic Toxicology. :125-155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b45a33d62ce6c094fe8d94abb34e68f1
https://doi.org/10.1002/9781119681397.ch7
https://doi.org/10.1002/9781119681397.ch7
Publikováno v:
Molecular Diversity
Scientific and consumer interest in healthy foods (also known as functional foods), nutraceuticals and cosmeceuticals has increased in the recent years, leading to an increased presence of these products in the market. However, the regulations across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b39ec90d19e41068626c387d1187ba
https://doi.org/10.1007/s11030-021-10277-5
https://doi.org/10.1007/s11030-021-10277-5