Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stephen J. Assinder"'
Autor:
Stephen J. Assinder, Vanitha Bhoopalan
Publikováno v:
Diagnostics, Vol 7, Iss 1, p 6 (2017)
It has been estimated that globally there is a death attributable to prostate cancer every four minutes. As life expectancy in all world regions increases, so too incidence of this disease of the ageing male will increase. For many men diagnosis occu
Externí odkaz:
https://doaj.org/article/cac273cd03b2474398b7c47ec09c7429
Autor:
Syer C. Lim, Zaklina Kovacevic, Patric J. Jansson, Des R. Richardson, Sanaz Maleki, Stephen J. Assinder
Publikováno v:
The FASEB Journal. 34:11511-11528
The androgen receptor (AR) is a major driver of prostate cancer (PCa) and a key therapeutic target for AR inhibitors (ie, Enzalutamide). However, Enzalutamide only inhibits androgen-dependent AR signaling, enabling intrinsic AR activation via androge
Autor:
Stephen J, Assinder
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2384
Oxytocin and oxytocin receptors are synthesized in the periphery where paracrine/autocrine actions have been described alongside endocrine actions effected by central release of oxytocin from the posterior pituitary. In the female reproductive system
Autor:
Badwi B. Boumelhem, Jacek L. Kolanowski, Stuart T. Fraser, Chelsea Pilgrim, Katrina A. Jolliffe, Elizabeth J. New, Margot L. Day, Stephen J. Assinder, Vincent E. Zwicker, Jia Hao Yeo
Publikováno v:
Journal of cell science. 135(5)
The lipid content of mammalian cells varies greatly between cell type. Current methods for analysing lipid components of cells are technically challenging and destructive. Here, we report a facile, inexpensive method to identify lipid content – int
Publikováno v:
Molecular and cellular endocrinology. 534
A model of oxytocin in the regulation of metabolic status has described one of oxytocin synthesis and release from the neurohypophysis in response to leptin, to suppress further leptin release. In addition, a lipogenic role for oxytocin has been sugg
Oxytocin stimulates lipolysis, prostaglandin E2 synthesis, and leptin secretion in 3T3-L1 adipocytes
Publikováno v:
Molecular and Cellular Endocrinology. 534:111381
A model of oxytocin in the regulation of metabolic status has described one of oxytocin synthesis and release from the neurohypophysis in response to leptin, to suppress further leptin release. In addition, a lipogenic role for oxytocin has been sugg
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2029
The urothelium of the bladder and urethra are derived from the definitive endoderm during development. Cellular signaling molecules important to the developmental specification of the urothelium are also implicated in the dysregulation of the tissue
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996308
The urothelium of the bladder and urethra are derived from the definitive endoderm during development. Cellular signaling molecules important to the developmental specification of the urothelium are also implicated in the dysregulation of the tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::597d9e7991ca644d8a9386c0e6b1523f
https://doi.org/10.1007/978-1-4939-9631-5_9
https://doi.org/10.1007/978-1-4939-9631-5_9
Publikováno v:
Adipocyte. 6(2)
Understanding adipose tissue heterogeneity is hindered by the paucity of methods to analyze mature adipocytes at the single cell level. Here, we report a system for analyzing live adipocytes from different adipose depots in the adult mouse. Single ce
Autor:
Mu Yao, Marzieh Niknami, Soma Vignarajan, Leila Hejazi, Qihan Dong, Zhen Gong, Des R. Richardson, Paul K. Witting, Stephen J. Assinder, Sheng Hua, Ying Teng
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:1146-1157
Constitutive phosphorylation of protein kinase B (AKT) is a common feature of cancer caused by genetic alteration in the phosphatase and tensin homolog (PTEN) gene and is associated with poor prognosis. This study determined the role of cytosolic pho