Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Stephen J Williams"'
Autor:
Pierluigi Scalia, Stephen J. Williams
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Recently published work provide the first known evidence of a malignancy-associated regulatory mechanism, functionally connecting a phospho-regulated degron domain embedded in a receptor tyrosine kinase (RTK), with its ectopic expression in cancer, c
Externí odkaz:
https://doaj.org/article/f25a6dd6e0464beaa2f64a2d63fa6562
Autor:
Adam C. Schneider, Michael C. Cushing, Robert A. Stiller, Jeffrey A. Munn, Frederick J. Vrba, Justice Bruursema, Stephen J. Williams, Michael C. Liu, Alexia Bravo, Jacqueline K. Faherty, Austin Rothermich, Emily Calamari, Dan Caselden, Martin Kabatnik, Arttu Sainio, Thomas P. Bickle, William Pendrill, Nikolaj Stevnbak Andersen, Melina Thévenot
Publikováno v:
The Astronomical Journal, Vol 168, Iss 4, p 165 (2024)
We have used the UKIRT Hemisphere Survey combined with the UKIDSS Galactic Cluster Survey, the UKIDSS Galactic Plane Survey, and the CatWISE2020 catalog to search for new substellar members of the nearest open cluster to the Sun, the Hyades. Eight ne
Externí odkaz:
https://doaj.org/article/93005704f93047cd96d8c1b3bcc0d382
Autor:
Pierluigi Scalia, Ignazio R. Marino, Salvatore Asero, Giuseppe Pandini, Adda Grimberg, Wafik S. El-Deiry, Stephen J. Williams
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 40 (2023)
The paraneoplastic syndrome referred in the literature as non-islet-cell tumor hypoglycemia (NICTH) and extra-pancreatic tumor hypoglycemia (EPTH) was first reported almost a century ago, and the role of cancer-secreted IGF-II in causing this blood g
Externí odkaz:
https://doaj.org/article/3c7870cc7551453b8fd353a4e829dc43
Autor:
Adam C. Schneider, Adam J. Burgasser, Justice Bruursema, Jeffrey A. Munn, Frederick J. Vrba, Dan Caselden, Martin Kabatnik, Austin Rothermich, Arttu Sainio, Thomas P. Bickle, Scott E. Dahm, Aaron M. Meisner, J. Davy Kirkpatrick, Genaro Suárez, Jonathan Gagné, Jacqueline K. Faherty, Johanna M. Vos, Marc J. Kuchner, Stephen J. Williams, Daniella Bardalez Gagliuffi, Christian Aganze, Chih-Chun Hsu, Christopher Theissen, Michael C. Cushing, Federico Marocco, Sarah Casewell, The Backyard Worlds: Planet 9 Collaboration
Publikováno v:
The Astrophysical Journal Letters, Vol 943, Iss 2, p L16 (2023)
We present the discovery of CWISE J050626.96+073842.4 (CWISE J0506+0738), an L/T transition dwarf with extremely red near-infrared colors discovered through the Backyard Worlds: Planet 9 citizen science project. Photometry from UKIRT and CatWISE give
Externí odkaz:
https://doaj.org/article/32c925b93a444637813f9fe405d28b9c
Publikováno v:
Cells, Vol 12, Iss 13, p 1680 (2023)
Until recently, Deltex (DTX) proteins have been considered putative E3 ligases, based on the presence of an E3 RING domain in their protein coding sequence. The human DTX family includes DTX1, DTX2, DTX3, DTX3L and DTX4. Despite the fact that our kno
Externí odkaz:
https://doaj.org/article/29860b8057544dc58d3d36c337a7dbb4
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1655 (2023)
Regulation of the human IGF2 gene displays multiple layers of control, which secures a genetically and epigenetically predetermined gene expression pattern throughout embryonal growth and postnatal life. These predominantly nuclear regulatory mechani
Externí odkaz:
https://doaj.org/article/7b555bc2a4f04424aa15368e65392194
Autor:
Pierluigi Scalia, Carmen Merali, Carlos Barrero, Antonio Suma, Vincenzo Carnevale, Salim Merali, Stephen J. Williams
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7380 (2023)
EphB4 angiogenic kinase over-expression in Mesothelioma cells relies upon a degradation rescue signal provided by autocrine IGF-II activation of Insulin Receptor A. However, the identity of the molecular machinery involved in EphB4 rapid degradation
Externí odkaz:
https://doaj.org/article/cf203344c2c04db588f9902480733f6f
Autor:
Adam C. Schneider, Jeffrey A. Munn, Frederick J. Vrba, Justice Bruursema, Scott E. Dahm, Stephen J. Williams, Michael C. Liu, Bryan N. Dorland
Publikováno v:
The Astronomical Journal, Vol 166, Iss 3, p 103 (2023)
We present the positions, proper motions, and near-infrared photometry for 966 known objects with spectral types later than M that were observed as part of the the UKIRT Hemisphere Survey (UHS). We augment the photometry and astrometry from UHS with
Externí odkaz:
https://doaj.org/article/4786891e36054da08b264823e41eff76
Publikováno v:
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 19, Iss , Pp - (2020)
Vascular bypass graft infection with Mycobacterium bovis following Bacillus Calmette–Guérin (BCG) immunotherapy for bladder cancer is an incredibly rare complication. We present the case of an 85-year-old man with a history of femorofemoral bypass
Externí odkaz:
https://doaj.org/article/ba14bbc7153541c0b94e7a5a32bd3473
Publikováno v:
Cell Cycle. 22:1-37
In proliferating cells and tissues a number of checkpoints (G1/S and G2/M) preceding cell division (M-phase) require the signal provided by growth factors present in serum. IGFs (I and II) have been demonstrated to constitute key intrinsic components