Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Stephen J Watt"'
Publikováno v:
JMIR Medical Informatics, Vol 12, Pp e64143-e64143 (2024)
AbstractCardiovascular drug development requires synthesizing relevant literature about indications, mechanisms, biomarkers, and outcomes. This short study investigates the performance, cost, and prompt engineering trade-offs of 3 large language mode
Externí odkaz:
https://doaj.org/article/33ad9fd0b283420d8275c624f05ac429
Autor:
Maggie Jalowsky BS, Brett Hauber PhD, Mariah Jacqueline Scott MS, MPH, Steven Arkin MD, Joshua R. Coulter MA, Stephen J Watt MD, L Mariah G Kelly RN, Ashley Valentine MRes
Publikováno v:
Journal of Patient Experience, Vol 10 (2023)
Involving patients as co-leaders and co-creators in research is key to reflecting the patient’s voice in decision-making. However, co-creation of patient-centered data to inform decisions is rare, especially in early drug development where patient
Externí odkaz:
https://doaj.org/article/8e69adb0d64d47c79bbbbf6ef04d8b11
Autor:
Stephen J Watt, Carlo R Carere, Sergio E. Morales, Chris Greening, Matthew C. Taylor, Gunjan Pandey, John G. Oakeshott, Matthew B. Stott, Andrew C. Warden, Colin J. Jackson, F. Hafna Ahmed, Ambarish Biswas, Blair Ney
Publikováno v:
The ISME Journal. 11:125-137
F420 is a low-potential redox cofactor that mediates the transformations of a wide range of complex organic compounds. Considered one of the rarest cofactors in biology, F420 is best known for its role in methanogenesis and has only been chemically i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c955b6aa865a7a7da597ad5da3dcde60
https://doi.org/10.1038/ismej.2016.100
https://doi.org/10.1038/ismej.2016.100
Autor:
Frank Sobott, Stephen J. Watt, Mariola J. Edelmann, Benedikt M. Kessler, Julia Smith, Holger B. Kramer
Ubiquitination has emerged as one of the major post-translational modifications that decide on protein fate, targeting, and regulation of protein function. Whereas the ubiquitination of proteins can be monitored with classic biochemical methods, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2155265d7fbff803db26e5bdf93b1c6d
https://doi.org/10.1016/j.jasms.2009.04.023
https://doi.org/10.1016/j.jasms.2009.04.023
Publikováno v:
2016 IEEE International Symposium on Antennas and Propagation (APSURSI).
In simultaneous transmit and receive (STAR) systems, multi-tap RF self-interference cancellation (RF-SIC) filters are employed to prevent receiver saturation and achieve STAR communication. Specifically, RF-SIC filters aim to reproduce the frequency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bfbe6710de8aa4bd60d1bacd906f064
https://doi.org/10.1109/aps.2016.7696765
https://doi.org/10.1109/aps.2016.7696765
Autor:
Tara L. Pukala, Rebecca J. Jackway, John H. Bowie, Stephen J. Watt, Jennifer L. Beck, Thitima Urathamakul
Publikováno v:
Rapid Communications in Mass Spectrometry. 22:3501-3509
Amphibian peptides which inhibit the formation of nitric oxide by neuronal nitric oxide synthase (nNOS) do so by binding to the protein cofactor, Ca 2+ calmodulin (Ca 2+ CaM). Complex formation between active peptides and Ca 2+ CaM has been demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2896768834fc1403edcc254cdbe27174
https://doi.org/10.1002/rcm.3757
https://doi.org/10.1002/rcm.3757
Autor:
Margaret M. Sheil, Jennifer L. Beck, Nicholas E. Dixon, Stephen J. Watt, Gottfried Otting, Pavel Prosselkov
Publikováno v:
Journal of the American Society for Mass Spectrometry. 18:1605-1611
Changes in protein conformation are thought to alter charge state distributions observed in electrospray ionization mass spectra (ESI-MS) of proteins. In most cases, this has been demonstrated by unfolding proteins through acidification of the soluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b3d5c04f05b7cce58f339e44de80b3
https://doi.org/10.1016/j.jasms.2007.06.004
https://doi.org/10.1016/j.jasms.2007.06.004
Autor:
Stephen J. Watt, J. Andrew Aquilina
Publikováno v:
Biochemical and Biophysical Research Communications. 353:1115-1120
Alpha-crystallin, a major structural protein of the lens can also function as a molecular chaperone by binding to unfolding substrate proteins. We have used a combination of limited proteolysis at low temperature, and mass spectrometry to identify th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff475d1f11107280cfb587ca1554387
https://doi.org/10.1016/j.bbrc.2006.12.176
https://doi.org/10.1016/j.bbrc.2006.12.176
Publikováno v:
2015 IEEE International Symposium on Antennas and Propagation & USNC/URSI National Radio Science Meeting.
To minimize self-interference in Simultaneous Transmit and Receive (STAR) communication systems, multi-tap analog cancelling filters are employed to emulate coupling between transmit and receive antennas. This paper presents the design and simulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3286c98f5dfcca76e956d3a1bbf3e72f
https://doi.org/10.1109/aps.2015.7304450
https://doi.org/10.1109/aps.2015.7304450
Autor:
Stephen J. Watt, John L. Volakis, Abe A. Akhiyat, Brian Dupaix, Elias A. Alwan, Waleed Khalil, Kevin L. Scherer
Publikováno v:
2015 IEEE International Symposium on Antennas and Propagation & USNC/URSI National Radio Science Meeting.
Simultaneous transmit and receive systems (STAR) are proposed to double the spectral efficiency and enhance spectrum utilization in the traditional microwave band. A major problem is high power self-interference (SI) due to the proximity of the trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90695f82687a8fa5a32b24999c5c1d31
https://doi.org/10.1109/aps.2015.7304646
https://doi.org/10.1109/aps.2015.7304646