Zobrazeno 1 - 10
of 607
pro vyhledávání: '"Stephen J Pandol"'
Autor:
Aileen Baecker, Sungjin Kim, Harvey A Risch, Teryl K Nuckols, Bechien U Wu, Andrew E Hendifar, Stephen J Pandol, Joseph R Pisegna, Christie Y Jeon
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218580 (2019)
Background and objectiveEarly detection methods for pancreatic cancer are lacking. We aimed to develop a prediction model for pancreatic cancer based on changes in health captured by healthcare claims data.MethodsWe conducted a case-control study on
Externí odkaz:
https://doaj.org/article/8b3a381ace224c44b38a296cb51fc924
Autor:
Jingzhen Yuan, Burcu Hasdemir, Tanya Tan, Chintan Chheda, Jean Rivier, Stephen J Pandol, Aditi Bhargava
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217065 (2019)
Because little is known about the role of corticotropin-releasing factor (CRF) agonists in regulating responses in pancreatitis, we evaluated the effects of urocortin 2 (UCN2) and stressin1 in caerulein-induced acute pancreatitis (AP) model in rats.
Externí odkaz:
https://doaj.org/article/7d6edc5ca6704b4ab4ee7f3796e459f6
Autor:
Hui-Hua Chang, Aune Moro, Kazuki Takakura, Hsin-Yuan Su, Allen Mo, Masako Nakanishi, Richard T Waldron, Samuel W French, David W Dawson, O Joe Hines, Gang Li, Vay Liang W Go, James Sinnett-Smith, Stephen J Pandol, Aurelia Lugea, Anna S Gukovskaya, Michael O Duff, Daniel W Rosenberg, Enrique Rozengurt, Guido Eibl
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184455 (2017)
Epidemiologic data has linked obesity to a higher risk of pancreatic cancer, but the underlying mechanisms are poorly understood. To allow for detailed mechanistic studies in a relevant model mimicking diet-induced obesity and pancreatic cancer, a hi
Externí odkaz:
https://doaj.org/article/65f6fd5020ab4c38a849f10b7bae4ca6
Autor:
Danmei Su, Airu Zhu, Yuanyang Nie, Zishuo Chen, Pengfei Wu, Li Zhang, Mei Luo, Qun Sun, Linbi Cai, Yuchen Lai, Zhixiong Xiao, Zhongping Duan, Sujun Zheng, Guihui Wu, Richard Hu, Hidekazu Tsukamoto, Aurelia Lugea, Stephen J Pandol, Yuan-Ping Han
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Metabolic syndrome (MetS), characterized as obesity, insulin resistance, and non-alcoholic fatty liver diseases (NAFLD),is associated with vitamin D insufficiency/deficiency in epidemiological studies, while the underlying mechanism is poorly addre
Externí odkaz:
https://doaj.org/article/22406adf9c4b4a769a18add0daca67a6
Autor:
Nurshad Ali, Silvana Debernardi, Evelyn Kurotova, Jian Tajbakhsh, Nirdesh K. Gupta, Stephen J. Pandol, Patrick Wilson, Stephen P. Pereira, Bill Greenhalf, Oleg Blyuss, Tatjana Crnogorac-Jurcevic
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related death worldwide. Up to now, no specific screening or diagnostic tests are available for early PDAC detection. As a result, most patients are diagnosed with advance
Externí odkaz:
https://doaj.org/article/10656395436a4094a4771fd148554943
Autor:
Hsin-Yuan Su, Richard T Waldron, Raymond Gong, V Krishnan Ramanujan, Stephen J Pandol, Aurelia Lugea
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148999 (2016)
Activated pancreatic stellate cells (PaSC) are key participants in the stroma of pancreatic cancer, secreting extracellular matrix proteins and inflammatory mediators. Tumors are poorly vascularized, creating metabolic stress conditions in cancer and
Externí odkaz:
https://doaj.org/article/dbde9737c9e849ce9561a79273e8a230
Autor:
Stephen J Pandol, Mouad eEdderkaoui
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Pancreatic ductal adenocarcinoma is a devastating disease characterized by a dense desmoplastic stroma. Chemo- and radio-therapeutic strategies based on targeting cancer cells have failed in improving the outcome of this cancer suggesting important r
Externí odkaz:
https://doaj.org/article/400efbc6c9e94ab5bf550205f0487d72
Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness
Autor:
Maria Hatziapostolou, Marina Koutsioumpa, Abed M. Zaitoun, Christos Polytarchou, Mouad Edderkaoui, Swapna Mahurkar-Joshi, Jayakumar Vadakekolathu, Daniel D'Andrea, Anna Rose Lay, Niki Christodoulou, Thuy Pham, Tung-On Yau, Christina Vorvis, Suchit Chatterji, Stephen J. Pandol, George A. Poultsides, David W. Dawson, Dileep N. Lobo, Dimitrios Iliopoulos
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 5, Pp 687-702 (2024)
Background and Aims: Decoding pancreatic ductal adenocarcinoma heterogeneity and the consequent therapeutic selection remains a challenge. We aimed to characterize epigenetically regulated pathways involved in pancreatic ductal adenocarcinoma progres
Externí odkaz:
https://doaj.org/article/ed3b70b9de5c43699e1addca71804e12
Autor:
Christie Y Jeon, Stephen J Pandol, Bechien Wu, Galen Cook-Wiens, Roberta A Gottlieb, C Noel Bairey Merz, Marc T Goodman
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128730 (2015)
Externí odkaz:
https://doaj.org/article/52b5814a399846b7b336aa07d7f7442d
Autor:
Christie Y Jeon, Stephen J Pandol, Bechien Wu, Galen Cook-Wiens, Roberta A Gottlieb, C Noel Bairey Merz, Marc T Goodman
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121783 (2015)
Pancreatic cancer has poor prognosis and existing interventions provide a modest benefit. Statin has anti-cancer properties that might enhance survival in pancreatic cancer patients. We sought to determine whether statin treatment after cancer diagno
Externí odkaz:
https://doaj.org/article/5851cc332ad3470aa7b61685b7528216