Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Stephen J Moore"'
1
Akademický článek
Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunity.
Autor: Stephanie Ascough, Rebecca J Ingram, Karen K Chu, Catherine J Reynolds, Julie A Musson, Mehmet Doganay, Gökhan Metan, Yusuf Ozkul, Les Baillie, Shiranee Sriskandan, Stephen J Moore, Theresa B Gallagher, Hugh Dyson, E Diane Williamson, John H Robinson, Bernard Maillere, Rosemary J Boyton, Daniel M Altmann
Publikováno v: PLoS Pathogens, Vol 10, Iss 5, p e1004085 (2014)
Bacillus anthracis produces a binary toxin composed of protective antigen (PA) and one of two subunits, lethal factor (LF) or edema factor (EF). Most studies have concentrated on induction of toxin-specific antibodies as the correlate of protective i
Externí odkaz: https://doaj.org/article/2a3497e4431447f1bf25d62970f3f8fb
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2
Akademický článek
Screening of peptide libraries against protective antigen of Bacillus anthracis in a disposable microfluidic cartridge.
Autor: Joshua M Kogot, Yanting Zhang, Stephen J Moore, Paul Pagano, Dimitra N Stratis-Cullum, David Chang-Yen, Marek Turewicz, Paul M Pellegrino, Andre de Fusco, H Tom Soh, Nancy E Stagliano
Publikováno v: PLoS ONE, Vol 6, Iss 11, p e26925 (2011)
Bacterial surface peptide display has gained popularity as a method of affinity reagent generation for a wide variety of applications ranging from drug discovery to pathogen detection. In order to isolate the bacterial clones that express peptides wi
Externí odkaz: https://doaj.org/article/694fa127694b47aaa600ab6704739303
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3
Akademický článek
Impact of HLA Polymorphism on the Immune Response to Bacillus Anthracis Protective Antigen in Vaccination versus Natural Infection
Autor: Stephanie Ascough, Rebecca J. Ingram, Karen K. Y. Chu, Stephen J. Moore, Theresa Gallagher, Hugh Dyson, Mehmet Doganay, Gökhan Metan, Yusuf Ozkul, Les Baillie, E. Diane Williamson, John H. Robinson, Bernard Maillere, Rosemary J. Boyton, Daniel M. Altmann
Publikováno v: Vaccines, Vol 10, Iss 10, p 1571 (2022)
The causative agent of anthrax, Bacillus anthracis, evades the host immune response and establishes infection through the production of binary exotoxins composed of Protective Antigen (PA) and one of two subunits, lethal factor (LF) or edema factor (
Externí odkaz: https://doaj.org/article/f4a45dbbf1d740b49ccfbc1e65929d9a
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4
A Probody T Cell–Engaging Bispecific Antibody Targeting EGFR and CD3 Inhibits Colon Cancer Growth with Limited Toxicity
Autor: Leila M. Boustany, Sherry L. LaPorte, Laurie Wong, Clayton White, Veena Vinod, Joel Shen, Wendy Yu, David Koditek, Michael B. Winter, Stephen J. Moore, Li Mei, Linnea Diep, Yuanhui Huang, Shouchun Liu, Olga Vasiljeva, Jim West, Jennifer Richardson, Bryan Irving, Marcia Belvin, W. Michael Kavanaugh
Publikováno v: Cancer Research. 82:4288-4298
T cell–engaging bispecific antibodies (TCB) are highly potent therapeutics that can recruit and activate cytotoxic T cells to stimulate an antitumor immune response. However, the development of TCBs against solid tumors has been limited by signific
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6b4893c7751bd28d4c0d28835d032b
https://doi.org/10.1158/0008-5472.can-21-2483
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