Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Stephen J Libby"'
Autor:
Sarah E Philo, Nicolette A Zhou, Lorraine M Lillis, Venkata Raghava, Dilip Abraham, Vinoth Kumar, Nirmal Kumar, Jonathan Rigby, Joanna Ciol Harrison, Christine S Fagnant-Sperati, Alexandra L Kossik, Angelo Q W Ong, Rachael Swanstrom, Elisabeth Burnor, Bethel Demeke, Nicola K Beck, Jeffry H Shirai, Stephen J Libby, David S Boyle, Nicholas Feasey, Gagandeep Kang, John Scott Meschke
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0301624 (2024)
Salmonella enterica serovar Typhi (S. Typhi) is the causative agent of Typhoid fever. Blood culture is the gold standard for clinical diagnosis, but this is often difficult to employ in resource limited settings. Environmental surveillance of waste-i
Externí odkaz:
https://doaj.org/article/ded1f68d5c724694b996ff43e517409d
Autor:
Dagmara I Kisiela, Sujay Chattopadhyay, Stephen J Libby, Joyce E Karlinsey, Ferric C Fang, Veronika Tchesnokova, Jeremy J Kramer, Viktoriya Beskhlebnaya, Mansour Samadpour, Krzysztof Grzymajlo, Maciej Ugorski, Emily W Lankau, Roderick I Mackie, Steven Clegg, Evgeni V Sokurenko
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002733 (2012)
Whereas the majority of pathogenic Salmonella serovars are capable of infecting many different animal species, typically producing a self-limited gastroenteritis, serovars with narrow host-specificity exhibit increased virulence and their infections
Externí odkaz:
https://doaj.org/article/5718067cd6364802a7764599f2dc22bd
Autor:
Anthony R Richardson, Khanh C Soliven, Margaret E Castor, Penelope D Barnes, Stephen J Libby, Ferric C Fang
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000451 (2009)
Intracellular pathogens must withstand nitric oxide (NO.) generated by host phagocytes. Salmonella enterica serovar Typhimurium interferes with intracellular trafficking of inducible nitric oxide synthase (iNOS) and possesses multiple systems to deto
Externí odkaz:
https://doaj.org/article/15e97fe3e0134252b1103e23fb839921
Autor:
Giannoula S Tansarli, Dustin R Long, Adam Waalkes, Lori A Bourassa, Stephen J Libby, Kelsi Penewit, Jared Almazan, Jason Matsumoto, Chloe Bryson-Cahn, Krista Rietberg, BreeAnna M Dell, Noël V Hatley, Stephen J Salipante, Ferric C Fang
Publikováno v:
The Lancet Infectious Diseases. 23:740-750
Autor:
W. Ryan Will, Peter Brzovic, Isolde Le Trong, Ronald E. Stenkamp, Matthew B. Lawrenz, Joyce E. Karlinsey, William W. Navarre, Kara Main-Hester, Virginia L. Miller, Stephen J. Libby, Ferric C. Fang
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Gene duplication and subsequent evolutionary divergence have allowed conserved proteins to develop unique roles. The MarR family of transcription factors (TFs) has undergone extensive duplication and diversification in bacteria, where they a
Externí odkaz:
https://doaj.org/article/6e89773f3ee944aa996a1cf09ab4bf04
Autor:
Elaine R. Frawley, Joyce E. Karlinsey, Anshika Singhal, Stephen J. Libby, Paschalis-Thomas Doulias, Harry Ischiropoulos, Ferric C. Fang
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Nitric oxide (NO·) produced by mammalian cells exerts antimicrobial actions that result primarily from the modification of protein thiols (S-nitrosylation) and metal centers. A comprehensive approach was used to identify novel targets of NO
Externí odkaz:
https://doaj.org/article/b1bf6fe5b949495ebbac88ff104fbf35
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT The Rcs phosphorelay and Psp (phage shock protein) systems are envelope stress responses that are highly conserved in gammaproteobacteria. The Rcs regulon was found to be strongly induced during metal deprivation of Salmonella enterica serov
Externí odkaz:
https://doaj.org/article/e45dd446afae4bac993976c697ee1195
Autor:
Matthew A. Crawford, Timothy Tapscott, Liam F. Fitzsimmons, Lin Liu, Aníbal M. Reyes, Stephen J. Libby, Madia Trujillo, Ferric C. Fang, Rafael Radi, Andrés Vázquez-Torres
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT The four-cysteine zinc finger motif of the bacterial RNA polymerase regulator DksA is essential for protein structure, canonical control of the stringent response to nutritional limitation, and thiol-based sensing of oxidative and nitrosativ
Externí odkaz:
https://doaj.org/article/0410db42924e46a1af7e678f52990e9d
Autor:
Larissa A. Singletary, Joyce E. Karlinsey, Stephen J. Libby, Jason P. Mooney, Kristen L. Lokken, Renée M. Tsolis, Mariana X. Byndloss, Lauren A. Hirao, Christopher A. Gaulke, Robert W. Crawford, Satya Dandekar, Robert A. Kingsley, Chisomo L. Msefula, Robert S. Heyderman, Ferric C. Fang
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Nontyphoidal Salmonella enterica serovar Typhimurium is a frequent cause of bloodstream infections in children and HIV-infected adults in sub-Saharan Africa. Most isolates from African patients with bacteremia belong to a single sequence typ
Externí odkaz:
https://doaj.org/article/18c0318f4ce24989a9672270a4aff640
Autor:
Shehla Yousuf, Christopher A. McDevitt, Stephen J. Libby, Ferric C. Fang, Joyce E. Karlinsey, Elaine R. Frawley, Stephanie L. Neville
Publikováno v:
Metallomics
Nitric oxide (NO˙) is a radical molecule produced by mammalian phagocytic cells as part of the innate immune response to bacterial pathogens. It exerts its antimicrobial activity in part by impairing the function of metalloproteins, particularly tho