Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Stephen J Fowler"'
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 26, Iss , Pp 9-19 (2022)
Antimicrobial resistance is increasing in prevalence and there is a clear need for the development of rapid detection methods in clinical diagnostics. This review explores –omics studies utilising mass spectrometry to investigate the molecular phen
Externí odkaz:
https://doaj.org/article/4180bb58d47e441a88a956a0804c16df
Autor:
Janelle Yorke, Stephen J Fowler, Jemma Haines, Jenny King, Jacklyn Ann Smith, James Wingfield-Digby
Publikováno v:
BMJ Open Respiratory Research, Vol 9, Iss 1 (2022)
Introduction Inducible laryngeal obstruction (ILO) describes transient laryngeal closure during respiration and can cause significant morbidity. Non-pharmacological behavioural therapy is the commonly cited treatment but efficacy is largely unknown.A
Externí odkaz:
https://doaj.org/article/0303069632734ca580c0b705d4700dca
Autor:
Richard Kwizera, Felix Bongomin, Ronald Olum, William Worodria, Freddie Bwanga, David B Meya, Bruce J Kirenga, Robin Gore, David W Denning, Stephen J Fowler
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252553 (2021)
BackgroundDiagnosis of fungal allergies in asthma remains problematic in low-and middle-income countries due to non-availability of point-of-care testing. In this study, we aimed to evaluate the performance of an Aspergillus immunochromatographic tec
Externí odkaz:
https://doaj.org/article/2d2584e926794581ac0ae186a2b5dec6
Publikováno v:
BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)
Introduction People with severe asthma experience unpredictable daily symptoms requiring an intense treatment regimen impacting on health-related quality of life (QoL). Sexuality contributes to this, yet there is a dearth of research exploring intima
Externí odkaz:
https://doaj.org/article/b68d5226ed91416d8d58ea1e1a31dadd
Autor:
Richard Kwizera, Joseph Musaazi, David B Meya, William Worodria, Freddie Bwanga, Henry Kajumbula, Stephen J Fowler, Bruce J Kirenga, Robin Gore, David W Denning
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216568 (2019)
BackgroundAsthma is one of the neglected diseases in Africa with a high prevalence. Allergic fungal diseases have been reported to complicate asthma progression and treatment outcomes. However, data about fungal asthma and its associated complication
Externí odkaz:
https://doaj.org/article/8418eee8c23a48608e0311ef8b3160ce
Autor:
Rosalia Emma, Aruna T Bansal, Johan Kolmert, Craig E Wheelock, Swen-Erik Dahlen, Matthew J Loza, Bertrand De Meulder, Diane Lefaudeux, Charles Auffray, Barbro Dahlen, Per S Bakke, Pascal Chanez, Stephen J Fowler, Ildiko Horvath, Paolo Montuschi, Norbert Krug, Marek Sanak, Thomas Sandstrom, Dominick E Shaw, Louise J Fleming, Ratko Djukanovic, Peter H Howarth, Florian Singer, Ana R Sousa, Peter J Sterk, Julie Corfield, Ioannis Pandis, Kian F Chung, Ian M Adcock, René Lutter, Lorena Fabbella, Massimo Caruso, U-BIOPRED Study Group
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203874 (2018)
Oxidative stress is believed to be a major driver of inflammation in smoking asthmatics. The U-BIOPRED project recruited a cohort of Severe Asthma smokers/ex-smokers (SAs/ex) and non-smokers (SAn) with extensive clinical and biomarker information ena
Externí odkaz:
https://doaj.org/article/a176a9f785e1455ab33c06826982b773
Publikováno v:
Analytical Science Advances. 4:104-131
Autor:
Ekaterina Khaleva, Anna Rattu, Chris Brightling, Andrew Bush, Arnaud Bourdin, Apostolos Bossios, Kian Fan Chung, Rekha Chaudhuri, Courtney Coleman, Ratko Djukanovic, Sven-Erik Dahlén, Andrew Exley, Louise Fleming, Stephen J. Fowler, Atul Gupta, Eckard Hamelmann, Gerard H. Koppelman, Erik Melén, Vera Mahler, Paul Seddon, Florian Singer, Celeste Porsbjerg, Valeria Ramiconi, Franca Rusconi, Valentyna Yasinska, Graham Roberts
Publikováno v:
Khaleva, E, Rattu, A, Brightling, C, Bush, A, Bourdin, A, Bossios, A, Chung, K F, Chaudhuri, R, Coleman, C, Djukanovic, R, Dahlén, S-E, Exley, A, Fleming, L, Fowler, S J, Gupta, A, Hamelmann, E, Koppelman, G H, Melén, E, Mahler, V, Seddon, P, Singer, F, Porsbjerg, C, Ramiconi, V, Rusconi, F, Yasinska, V & Roberts, G 2023, ' Definitions of non-response and response to biological therapy for severe asthma : a systematic review ', ERJ Open Research, vol. 9, no. 3, pp. 00444-2022 . https://doi.org/10.1183/23120541.00444-2022
BackgroundBiologics have proven efficacy for patients with severe asthma but there is lack of consensus on defining response. We systematically reviewed and appraised methodologically developed, defined and evaluated definitions of non-response and r
Autor:
P. Jane McDowell, John Busby, Catherine E. Hanratty, Ratko Djukanovic, Ashley Woodcock, Samantha Walker, Timothy Colin Hardman, Joseph R. Arron, David F. Choy, Peter Bradding, Chris E. Brightling, Rekha Chaudhuri, Douglas Cowan, Adel H. Mansur, Stephen J. Fowler, Sarah E. Diver, Peter Howarth, James Lordan, Andrew Menzies-Gow, Timothy Harrison, Douglas S. Robinson, Cecile T. J. Holweg, John G. Matthews, Ian D. Pavord, Liam G. Heaney
Publikováno v:
Am J Respir Crit Care Med
Rationale: The past 25 years have seen huge progress in understanding of the pathobiology of type-2 (T2) asthma, identification of measurable biomarkers, and the emergence of novel monoclonal antibody treatments. Although present in a minority of pat
Autor:
Benjamin Gaston, Donna D. Gardner, Kenzie Mahan, Praveen Akuthota, Eneida A. Mendonca, Hannah Durrington, Nadzeya Marozkina, Rocio T. Martinez-Nunez, Dawn Newcomb, Benjamin Ainsworth, Arthur H. Owora, Kian Fan Chung, Samantha Walker, Stephen J. Fowler, Salman Siddiqui, Tonya Winders, Joe Zein, Nizar Jarjour, Yvonne J. Huang, Katherine N. Cahill, Ratko Djukanovic
Publikováno v:
Gaston, B, Gardner, D D, Mahan, K, Akuthota, P, Mendonca, E A, Durrington, H, Marozkina, N, Martinez-Nunez, R T, Newcomb, D, Ainsworth, B, Owora, A H, Chung, K F, Walker, S, Fowler, S J, Siddiqui, S, Winders, T, Zein, J, Jarjour, N, Huang, Y J, Cahill, K N & Djukanovic, R 2023, ' Asthma innovations from the first International Collaborative Asthma Network forum ', ERJ Open Research, vol. 9, no. 3 . https://doi.org/10.1183/23120541.00090-2023
Many patients have uncontrolled asthma despite available treatments. Most of the new asthma therapies have focused on Type-2 (T2) inflammation, leaving an unmet need for innovative research into mechanisms of asthma beyond T2 and immunity. An interna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec9b54e200560e0ffb33ec7d1b8ca6e
https://doi.org/10.1183/23120541.00090-2023
https://doi.org/10.1183/23120541.00090-2023