Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Stephen J Evans"'
Autor:
Irene Petersen, Rachel L McCrea, Cormac J Sammon, David PJ Osborn, Stephen J Evans, Phillip J Cowen, Nick Freemantle, Irwin Nazareth
Publikováno v:
Health Technology Assessment, Vol 20, Iss 23 (2016)
Background: Although many women treated with psychotropic medication become pregnant, no psychotropic medication has been licensed for use in pregnancy. This leaves women and their health-care professionals in a treatment dilemma, as they need to bal
Externí odkaz:
https://doaj.org/article/e2fa027d51ba4c3297d56c7b44de6a9b
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Exposure to indoor air pollutants (IAP) has increased recently, with people spending more time indoors (i.e. homes, offices, schools and transportation). Increased exposures of IAP on a healthy population are poorly understood, and those wit
Externí odkaz:
https://doaj.org/article/d88f71a43d4c4005b226889c26edd53f
Publikováno v:
PLoS Medicine, Vol 6, Iss 9, p e1000154 (2009)
The results of clinical trials have suggested that the thiazolidinedione antidiabetic agents rosiglitazone and pioglitazone are associated with an increased risk of fractures, but such studies had limited power. The increased risk in these trials app
Externí odkaz:
https://doaj.org/article/d77a032f26f744d3a3f8367e812aeef2
Autor:
Scott Brown, Stephen J. Evans, Michael J. Burgum, Kirsty Meldrum, Jack Herridge, Blessing Akinbola, Llinos G. Harris, Rowena Jenkins, Shareen H. Doak, Martin J. D. Clift, Thomas S. Wilkinson
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 128 (2024)
The exposure of human lung and skin to carbon black (CB) is continuous due to its widespread applications. Current toxicological testing uses ‘healthy’ cellular systems; however, questions remain whether this mimics the everyday stresses that hum
Externí odkaz:
https://doaj.org/article/1d088c9d6c3e4db789994203ea74b278
Autor:
Michael J. Burgum, Martin J. D. Clift, Stephen J. Evans, Nicole Hondow, Afshin Tarat, Gareth J. Jenkins, Shareen H. Doak
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Toxicological evaluation of engineered nanomaterials (ENMs) is essential for occupational health and safety, particularly where bulk manufactured ENMs such as few-layer graphene (FLG) are concerned. Additionally, there is a necess
Externí odkaz:
https://doaj.org/article/7511988feba04f699dff1bcc0f42b3c6
Publikováno v:
Annals of Work Exposures and Health. 67:i44-i45
Exposure to indoor air pollutants (IAP) has increased recently, with people spending more time indoors. Increased exposures of IAP on a healthy population are poorly understood, and those with allergic respiratory conditions less so. The objective of
Autor:
Angela Saccardo, Stephen J Evans, Mariajose Lopez Tendero, José Balbuena, José M L Cormano, Gareth J S Jenkins, Martin J D Clift, Shareen H Doak
Publikováno v:
Annals of Work Exposures and Health. 67:i60-i61
The development of nanomaterials has seen exponential growth in the last two decades and, more recently, of complex multicomponent nanomaterials (MCNM), which represent challenges for human hazard testing. This study aims to determine exposure-dose-r
Autor:
Raffaella Corvi, Stephen J. Evans, Shareen H. Doak, Gilly Stoddart, Samantha Saunders, Stefan Pfuhler, Katherine Groff
Publikováno v:
Mutagenesis. 36:389-400
Abstract Scientific, financial, and ethical drivers have led to unprecedented interest in implementing human-relevant, mechanistic in vitro and in silico testing approaches. Further, as non-animal approaches are being developed and validated, researc
Autor:
Martin J. D. Clift, Gillian E. Conway, Tereza Cervena, Gareth J.S. Jenkins, Ume-Kulsoom Shah, Abdullah S Al Ali, Shareen H. Doak, Samantha V. Llewellyn, Stephen J. Evans
Publikováno v:
Mutagenesis
Following advancements in the field of genotoxicology, it has become widely accepted that 3D models are not only more physiologically relevant but also have the capacity to elucidate more complex biological processes that standard 2D monocultures are
Autor:
Stephen J Evans, Julia Fernando, Kirsty Meldrum, Michael J Burgum, Shareen H Doak, Martin J D Clift
Publikováno v:
Annals of Work Exposures and Health. 67:i58-i58
A primary toxicological focus has been the development of cellular models and exposure systems representative of nanomaterial inhalation due to the inevitable risk of environmental or occupational exposure. This current study compared the genotoxic a