Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Stephen J Evans"'
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Exposure to indoor air pollutants (IAP) has increased recently, with people spending more time indoors (i.e. homes, offices, schools and transportation). Increased exposures of IAP on a healthy population are poorly understood, and those wit
Externí odkaz:
https://doaj.org/article/d88f71a43d4c4005b226889c26edd53f
Autor:
Scott Brown, Stephen J. Evans, Michael J. Burgum, Kirsty Meldrum, Jack Herridge, Blessing Akinbola, Llinos G. Harris, Rowena Jenkins, Shareen H. Doak, Martin J. D. Clift, Thomas S. Wilkinson
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 128 (2024)
The exposure of human lung and skin to carbon black (CB) is continuous due to its widespread applications. Current toxicological testing uses ‘healthy’ cellular systems; however, questions remain whether this mimics the everyday stresses that hum
Externí odkaz:
https://doaj.org/article/1d088c9d6c3e4db789994203ea74b278
Autor:
Michael J. Burgum, Martin J. D. Clift, Stephen J. Evans, Nicole Hondow, Afshin Tarat, Gareth J. Jenkins, Shareen H. Doak
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Toxicological evaluation of engineered nanomaterials (ENMs) is essential for occupational health and safety, particularly where bulk manufactured ENMs such as few-layer graphene (FLG) are concerned. Additionally, there is a necess
Externí odkaz:
https://doaj.org/article/7511988feba04f699dff1bcc0f42b3c6
Autor:
Stephen J. Evans, Martin J. D. Clift, Neenu Singh, John W. Wills, Nicole Hondow, Thomas S. Wilkinson, Michael J. Burgum, Andy P. Brown, Gareth J. Jenkins, Shareen H. Doak
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background It is well established that toxicological evaluation of engineered nanomaterials (NMs) is vital to ensure the health and safety of those exposed to them. Further, there is a distinct need for the development of advanced physiologi
Externí odkaz:
https://doaj.org/article/dec2e27c1c4e4f959e7e1a2b2e8b27fe
Autor:
Ane Ruiz-de-Angulo, Marc Bilbao-Asensio, James Cronin, Stephen J. Evans, Martin J.D. Clift, Jordi Llop, Irene V.J. Feiner, Rhiannon Beadman, Kepa Zamacola Bascarán, Juan C. Mareque-Rivas
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101499- (2020)
Summary: Immunotherapy has yielded impressive results, but only for a minority of patients with cancer. Therefore, new approaches that potentiate immunotherapy are a pressing medical need. Ferroptosis is a newly described type of programmed cell deat
Externí odkaz:
https://doaj.org/article/a5826939d70947b2815106ea34cb9aab
Publikováno v:
Annals of Work Exposures and Health. 67:i44-i45
Exposure to indoor air pollutants (IAP) has increased recently, with people spending more time indoors. Increased exposures of IAP on a healthy population are poorly understood, and those with allergic respiratory conditions less so. The objective of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf78f97087b1dd590a5cfd7e2ea6d788
https://doi.org/10.1093/annweh/wxac087.108
https://doi.org/10.1093/annweh/wxac087.108
Autor:
Angela Saccardo, Stephen J Evans, Mariajose Lopez Tendero, José Balbuena, José M L Cormano, Gareth J S Jenkins, Martin J D Clift, Shareen H Doak
Publikováno v:
Annals of Work Exposures and Health. 67:i60-i61
The development of nanomaterials has seen exponential growth in the last two decades and, more recently, of complex multicomponent nanomaterials (MCNM), which represent challenges for human hazard testing. This study aims to determine exposure-dose-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20854491f3bb793451dabb84269996b9
https://doi.org/10.1093/annweh/wxac087.146
https://doi.org/10.1093/annweh/wxac087.146
Autor:
Raffaella Corvi, Stephen J. Evans, Shareen H. Doak, Gilly Stoddart, Samantha Saunders, Stefan Pfuhler, Katherine Groff
Publikováno v:
Mutagenesis. 36:389-400
Abstract Scientific, financial, and ethical drivers have led to unprecedented interest in implementing human-relevant, mechanistic in vitro and in silico testing approaches. Further, as non-animal approaches are being developed and validated, researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6648e6e26259f992a7fcefce147a0716
https://doi.org/10.1093/mutage/geab035
https://doi.org/10.1093/mutage/geab035
Autor:
Martin J. D. Clift, Gillian E. Conway, Tereza Cervena, Gareth J.S. Jenkins, Ume-Kulsoom Shah, Abdullah S Al Ali, Shareen H. Doak, Samantha V. Llewellyn, Stephen J. Evans
Publikováno v:
Mutagenesis
Following advancements in the field of genotoxicology, it has become widely accepted that 3D models are not only more physiologically relevant but also have the capacity to elucidate more complex biological processes that standard 2D monocultures are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4511305c9ae8085d0d46faa3aead79a3
https://doi.org/10.1093/mutage/geab013
https://doi.org/10.1093/mutage/geab013
Autor:
Stephen J Evans, Julia Fernando, Kirsty Meldrum, Michael J Burgum, Shareen H Doak, Martin J D Clift
Publikováno v:
Annals of Work Exposures and Health. 67:i58-i58
A primary toxicological focus has been the development of cellular models and exposure systems representative of nanomaterial inhalation due to the inevitable risk of environmental or occupational exposure. This current study compared the genotoxic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::720abbd783ca992b1c3d2e75d3720365
https://doi.org/10.1093/annweh/wxac087.140
https://doi.org/10.1093/annweh/wxac087.140