Zobrazeno 1 - 2
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pro vyhledávání: '"Stephen J Coultrap"'
Publikováno v:
Journal of Neurochemistry. 115:1112-1122
Alcohol abuse leads to tolerance, dependence, and memory impairments that involve excitatory glutamatergic NMDA synaptic transmission. The NMDA receptor (NMDAR) is known to undergo activity-dependent adaptive functional changes. Since we observed tha
Publikováno v:
Molecular pharmacology. 80(3)
The hippocampal N-methyl-d-aspartate receptor (NMDAR) activity plays important roles in cognition and is a major substrate for ethanol-induced memory dysfunction. This receptor is a glutamate-gated ion channel, which is composed of NR1 and NR2 subuni