Zobrazeno 1 - 10
of 332
pro vyhledávání: '"Stephen J, Wigmore"'
Publikováno v:
BMJ Open, Vol 14, Iss 8 (2024)
Introduction The efficiency of multidisciplinary teams (MDTs) in cancer care hinges on facilitating clinicians’ cognitive processes as they navigate complex and uncertain judgements during treatment planning. When systems and workflows are not desi
Externí odkaz:
https://doaj.org/article/ceadb0684bf94574a10e2b255203bcc1
Autor:
Ruridh Allen, MRCP, Chris J.C. Johnston, PhD, FRCS, Sarah Thomasset, PhD, FRCS, Rajan Ravindran, MS, FRCS, Stephen J. Wigmore, MD, FRCS, Nick I. Church, MD, FRCP
Publikováno v:
VideoGIE, Vol 8, Iss 11, Pp 464-468 (2023)
Externí odkaz:
https://doaj.org/article/e2540d50ab25439295e2604acc1bb975
Skeletal muscle analysis of cancer patients reveals a potential role for carnosine in muscle wasting
Autor:
Dheeraj Kumar Posa, Janice Miller, David Hoetker, Michael I. Ramage, Hong Gao, Jingjing Zhao, Benjamin Doelling, Aruni Bhatnagar, Stephen J. Wigmore, Richard J.E. Skipworth, Shahid P. Baba
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1802-1814 (2023)
Abstract Background Muscle wasting during cancer cachexia is mediated by protein degradation via autophagy and ubiquitin‐linked proteolysis. These processes are sensitive to changes in intracellular pH ([pH]i) and reactive oxygen species, which in
Externí odkaz:
https://doaj.org/article/c02fd9a25f77491299b8f06183dad31a
Autor:
Ewen M Harrison, Stephen R Knight, Thomas M Drake, Kenneth A McLean, Alessandro Sgrò, Stephen J Wigmore, Riinu Pius, William A Cambridge, Julian Camilleri-Brennan, Diana A Wu
Publikováno v:
BMJ Open, Vol 13, Iss 8 (2023)
Objective To identify whether socioeconomic deprivation is associated with worse health-related quality of life (HR-QoL), anxiety and depression following liver transplantation.Design Cross-sectional study.Setting and participants Liver transplant re
Externí odkaz:
https://doaj.org/article/01586ea76e10441ba22b9bc833a66d77
Autor:
Cameron J. Fairfield, Thomas M. Drake, Riinu Pius, Andrew D. Bretherick, Archie Campbell, David W. Clark, Jonathan A. Fallowfield, Caroline Hayward, Neil C. Henderson, Peter K. Joshi, Nicholas L. Mills, David J. Porteous, Prakash Ramachandran, Robert K. Semple, Catherine A. Shaw, Cathie L.M. Sudlow, Paul R.H.J. Timmers, James F. Wilson, Stephen J. Wigmore, Ewen M. Harrison, Athina Spiliopoulou
Publikováno v:
Hepatology Communications, Vol 6, Iss 2, Pp 297-308 (2022)
Genome‐wide association studies (GWAS) have identified several risk loci for nonalcoholic fatty liver disease (NAFLD). Previous studies have largely relied on small sample sizes and have assessed quantitative traits. We performed a case‐control G
Externí odkaz:
https://doaj.org/article/6838532b13294c6fa646e1703e80f182
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Introduction Surgeons need high fidelity, high quality, objective, non-judgemental and quantitative feedback to measure their performance in order to optimise their performance and improve patient safety. This can be provided through surgical saberme
Externí odkaz:
https://doaj.org/article/f1983219f8d146f1aadcec589082c134
Autor:
Kenneth A. McLean, Katie E. Mountain, Catherine A. Shaw, Thomas M. Drake, Riinu Pius, Stephen R. Knight, Cameron J. Fairfield, Alessandro Sgrò, Matt Bouamrane, William A. Cambridge, Mathew Lyons, Aya Riad, Richard J. E. Skipworth, Stephen J. Wigmore, Mark A. Potter, Ewen M. Harrison, TWIST Collaborators
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-9 (2021)
Abstract Surgical site infections (SSI) cause substantial morbidity and pose a burden to acute healthcare services after surgery. We aimed to investigate whether a smartphone-delivered wound assessment tool can expedite diagnosis and treatment of SSI
Externí odkaz:
https://doaj.org/article/ac3ff51ec06c40639ad19df305de1632
Autor:
Janice Miller, Gillian Dreczkowski, Michael I. Ramage, Stephen J. Wigmore, Iain J. Gallagher, Richard J.E. Skipworth
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 4, Pp 1141-1153 (2020)
Abstract Background Cancer cachexia is a poorly understood metabolic consequence of cancer. During cachexia, different adipose depots demonstrate differential wasting rates. Animal models suggest adipose tissue may be a key driver of muscle wasting t
Externí odkaz:
https://doaj.org/article/340e8ab0e8df4799a095196c862120dd
Autor:
Emma E Howie, Harini Dharanikota, Eilidh Gunn, Olivia Ambler, Roger Dias, Stephen J. Wigmore, Richard J.E. Skipworth, Steven Yule
Publikováno v:
Journal of Surgical Education. 80:311-322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0181e9d54e4fcbadafefef059245b529
https://doi.org/10.1016/j.jsurg.2022.12.010
https://doi.org/10.1016/j.jsurg.2022.12.010
Autor:
Katie L. Connor, Oliver Teenan, Carolynn Cairns, Victoria Banwell, Rachel A.B. Thomas, Julie Rodor, Sarah Finnie, Riinu Pius, Gillian M. Tannahill, Vishal Sahni, Caroline O.S. Savage, Jeremy Hughes, Ewen M. Harrison, Robert B. Henderson, Lorna P. Marson, Bryan R. Conway, Stephen J. Wigmore, Laura Denby
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Small noncoding RNAs, miRNAs (miRNAs), are emerging as important modulators in the pathogenesis of kidney disease, with potential as biomarkers of kidney disease onset, progression, or therapeutic efficacy. Bulk tissue small RNA-sequencing (sRNA-Seq)
Externí odkaz:
https://doaj.org/article/0e57397672654b13af1fc22e1d4a45d8