Zobrazeno 1 - 10
of 728
pro vyhledávání: '"Stephen J, Simpson"'
Autor:
Kathryn M. Farris, Alistair M. Senior, Débora R. Sobreira, Robert M. Mitchell, Zachary T. Weber, Lars R. Ingerslev, Romain Barrès, Stephen J. Simpson, Angela J. Crean, Marcelo A. Nobrega
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Diet is a key lifestyle component that influences metabolic health through several factors, including total energy intake and macronutrient composition. While the impact of caloric intake on gene expression and physiological phenomena in var
Externí odkaz:
https://doaj.org/article/7dbebc4349a940b19cdb5cc883a0451e
Autor:
Rebecca Luong, Rosilene V Ribeiro, Vasant Hirani, Stephen J Simpson, David G Le Couteur, David Raubenheimer, Alison K Gosby
Publikováno v:
Public Health Nutrition, Vol 26, Pp 3023-3037 (2023)
Abstract Objective: Diets with a low proportion of energy from protein have shown to cause overconsumption of non-protein energy, known as Protein Leverage. Older adults are susceptible to nutritional inadequacy. The aim was to investigate associati
Externí odkaz:
https://doaj.org/article/39bd3dae05b749278c60affe9ec2fba0
Autor:
Jibran A. Wali, Duan Ni, Harrison J. W. Facey, Tim Dodgson, Tamara J. Pulpitel, Alistair M. Senior, David Raubenheimer, Laurence Macia, Stephen J. Simpson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The metabolic effects of sugars and fat lie at the heart of the “carbohydrate vs fat” debate on the global obesity epidemic. Here, we use nutritional geometry to systematically investigate the interaction between dietary fat and the majo
Externí odkaz:
https://doaj.org/article/f5a90d3a385d45ddb77b2968864670c5
Autor:
Mirei Okada, Melissa J. Pehlivan, Jane Miskovic-Wheatley, Sarah Barakat, Kristi R. Griffiths, Stephen W. Touyz, Stephen J. Simpson, Sarah Maguire, Andrew J. Holmes
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionSelf-directed dieting (i.e., unsupervised) is very common among adolescents and young adults but has had almost no direct research. This paper describes the protocol for the My Diet Study, a two-arm observational investigation of the natu
Externí odkaz:
https://doaj.org/article/141ccbcc9d4b49438913a11623738f7b
Autor:
Samantha M. Solon-Biet, Ximonie Clark, Kim Bell-Anderson, Patricia M. Rusu, Ruth Perks, Therese Freire, Tamara Pulpitel, Alistair M. Senior, Andrew J. Hoy, Okka Aung, David G. Le Couteur, David Raubenheimer, Adam J. Rose, Arthur D. Conigrave, Stephen J. Simpson
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113536- (2023)
Summary: Fibroblast growth factor 21 (FGF21), an endocrine signal robustly increased by protein restriction independently of an animal’s energy status, exerts profound effects on feeding behavior and metabolism. Here, we demonstrate that considerin
Externí odkaz:
https://doaj.org/article/67b2b68aaa1d44e198ce08c2781e6b02
Autor:
Jian Tan, Rosilene V. Ribeiro, Christopher Barker, Claire Daien, Erick De Abreu Silveira, Andrew Holmes, Ralph Nanan, Stephen J. Simpson, Laurence Macia
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTDietary fiber plays a crucial role in maintaining gut and overall health. The objective of this study was to investigate whether different types of dietary fiber elicited specific changes in gut microbiota composition and the production of sh
Externí odkaz:
https://doaj.org/article/c26ec314093d49c0a5bc8c20b2bf96b6
Autor:
Wanchuang Zhu, Roman Marchant, Richard W. Morris, Louise A. Baur, Stephen J. Simpson, Sally Cripps
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background When tackling complex public health challenges such as childhood obesity, interventions focused on immediate causes, such as poor diet and physical inactivity, have had limited success, largely because upstream root causes remain
Externí odkaz:
https://doaj.org/article/b8e8c5423b3f43deb4ed1585e0c700f6
Autor:
Alistair M. Senior, Véronique Legault, Francis B. Lavoie, Nancy Presse, Pierrette Gaudreau, Valérie Turcot, David Raubenheimer, David G. Le Couteur, Stephen J. Simpson, Alan A. Cohen
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Little is known about how normal variation in dietary patterns in humans affects the ageing process. To date, most analyses of the problem have used a unidimensional paradigm, being concerned with the effects of a single nutrient
Externí odkaz:
https://doaj.org/article/03a2395839b541ea9cc6137260cf87e6
Autor:
Jian Tan, Duan Ni, Jemma Taitz, Gabriela Veronica Pinget, Mark Read, Alistair Senior, Jibran Abdul Wali, Reem Elnour, Erin Shanahan, Huiling Wu, Steven J. Chadban, Ralph Nanan, Nicholas Jonathan Cole King, Georges Emile Grau, Stephen J. Simpson, Laurence Macia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Secretory IgA plays vital roles interfacing between the host immune system and the resident microbiota at the mucosal surface. Here the authors explore the effect of dietary protein on the production of secretory IgA, driven by the production of extr
Externí odkaz:
https://doaj.org/article/1a558a672c5147d9bc844ff084a46355
Autor:
Samantha M. Solon-Biet, Lucy Griffiths, Sophie Fosh, David G. Le Couteur, Stephen J. Simpson, Alistair M. Senior
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The role of dietary branched chain amino acids (BCAAs) and their effect on metabolic health is complex. How dietary BCAA levels and their interaction with background nutrition affect health is unclear. Here, we used meta-analysis
Externí odkaz:
https://doaj.org/article/9aba48b7982f47f2a756a6c4bd886f16