Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Stephen J, Gandy"'
Autor:
Jonathan R. Weir-McCall, Matthew Lambert, Stephen J. Gandy, Jill J. F. Belch, Ian Cavin, Shelley A. Henderson, Roberta Littleford, Jennifer A. Macfarlane, Shona Z. Matthew, R. Stephen Nicholas, Allan D. Struthers, Frank Sullivan, Richard D. White, J. Graeme Houston
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background Arteriosclerosis (arterial stiffening) is associated with future cardiovascular events, with this effect postulated to be due to its effect on cardiac afterload, atherosclerosis (plaque formation) progression or both, but with lim
Externí odkaz:
https://doaj.org/article/e78a96c2264e4fc3b2609d3ac6ba7055
Autor:
Jonathan R Weir-McCall, Faisel Khan, Deirdre B Cassidy, Arsh Thakur, Jennifer Summersgill, Shona Z Matthew, Fiona Adams, Fiona Dove, Stephen J Gandy, Helen M Colhoun, Jill JF Belch, J Graeme Houston
Publikováno v:
BMC Cardiovascular Disorders, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Carotid-femoral pulse wave velocity (cf-PWV) and aortic PWV measured using MRI (MRI-PWV) show good correlation, but with a significant and consistent bias across studies. The aim of the current study was to evaluate whether the di
Externí odkaz:
https://doaj.org/article/a10199071a8f4ccf9a0a527355facf51
Autor:
Deepa Sumukadas, S. Richard Nicholas, Clare Clarke, Miles D. Witham, Anita Hutcheon, Christopher Gingles, Jacob George, Allan D. Struthers, Lukasz Priba, Ian Cavin, Rebecca R. Chungath, Stephen J. Gandy
Publikováno v:
JCSM Clinical Reports. 6:71-79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b9025dc24dd21834c49cfa3ef46673c
https://doi.org/10.1002/crt2.33
https://doi.org/10.1002/crt2.33
Autor:
A Hutcheon, Jacob George, L Priba, R R Chungath, Deepa Sumukadas, Stephen J. Gandy, Miles D. Witham, C Gingles, Clare Clarke, A D Struthers, S Nicholas, Ian Cavin
Publikováno v:
Age and Ageing. 50:i12-i42
Background Mitochondrial dysfunction has been proposed as a therapeutic target to improve muscle strength and endurance, but the contribution that mitochondrial dysfunction makes to impaired skeletal muscle performance in older people remains unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e12db5c591a5a48d363fe337c90ece5
https://doi.org/10.1093/ageing/afab030.03
https://doi.org/10.1093/ageing/afab030.03
Autor:
Alan G. Jardine, Allan D. Struthers, J. Graeme Houston, Rosemary Woodward, Elaine Rutherford, Graham A. Stewart, Sheila Ireland, Stephen J. Gandy, Petra Rauchhaus, Miles D. Witham, Kenneth Mangion, Giles Roditi, Patrick B. Mark, Mark S. MacGregor
Publikováno v:
Kidney International Reports
Introduction Increased left ventricular mass index (LVMI) is associated with mortality in end-stage renal disease. LVMI regression may improve outcomes. Allopurinol has reduced LVMI in randomized controlled trials in chronic kidney disease, diabetes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f20e2ecb88a9aeeb79fb0c90052ac78
http://europepmc.org/articles/PMC7783562
http://europepmc.org/articles/PMC7783562
Autor:
Ian Cavin, Stephen J. Gandy, Allan D. Struthers, Christopher Gingles, Clare Clarke, Deepa Sumukadas, Lukasz Priba, Jacob George, R S Nicholas, Anita Hutcheon, Miles D. Witham
Publikováno v:
Age and Ageing
Background Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e663f987b1fbf51c133da29805a128d
https://doi.org/10.1093/ageing/afaa061
https://doi.org/10.1093/ageing/afaa061
Autor:
Ewan R. Pearson, Jagdeep Singh, Anna Maria Choy, Stephen J. Gandy, J. Graeme Houston, Ify R. Mordi, Amir Fathi, Mohapradeep Mohan, Jacob George, Keeran Vickneson, Faisel Khan, Peter T. Donnan, Allan D. Struthers, Chim C. Lang
Publikováno v:
Diabetes Care
OBJECTIVE To determine the effects of dapagliflozin in patients with heart failure (HF) and type 2 diabetes mellitus (T2DM) on left ventricular (LV) remodeling using cardiac MRI. RESEARCH DESIGN AND METHODS We randomized 56 patients with T2DM and HF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b2e8a2f28e087ec1e615ca5ff4e3ae
https://doi.org/10.2337/dc19-2187
https://doi.org/10.2337/dc19-2187
Autor:
Christopher R, Gingles, Ruth, Symon, Stephen J, Gandy, Allan D, Struthers, Graeme, Houston, Thomas M, MacDonald, Chim C, Lang, Peter T, Donnan, Jacob, George
Publikováno v:
Journal of Hypertension
Objectives: Previous studies have demonstrated that high-dose allopurinol is able to regress left ventricular (LV) mass in cohorts with established cardiovascular disease. The aim of this study was to assess whether treatment with high-dose allopurin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4bf41ad2613f22cbc7a8e04449103b9c
http://europepmc.org/articles/PMC6855336
http://europepmc.org/articles/PMC6855336
Autor:
Jacob George, John Graeme Houston, Shona Z. Matthew, U Bhalraam, Fatima Baig, Ify Mordi, Faisel Khan, Jagdeep Singh, Allan D. Struthers, Angela McKinnie, Anna Maria Choy, Shaween Al-Talabany, Chim C. Lang, Mohapradeep Mohan, Muhammad S. Hussain, Stephen J. Gandy
Publikováno v:
European Heart Journal
Aim We tested the hypothesis that metformin may regress left ventricular hypertrophy (LVH) in patients who have coronary artery disease (CAD), with insulin resistance (IR) and/or pre-diabetes. Methods and results We randomly assigned 68 patients (mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35815d4caaed3323b79f626492d815a4
https://doi.org/10.1093/eurheartj/ehz203
https://doi.org/10.1093/eurheartj/ehz203
Autor:
Jonathan R Weir-McCall, Faisel Khan, Matthew A Lambert, Carly L Adamson, Michael Gardner, Stephen J Gandy, Prasad Guntur Ramkumar, Jill J F Belch, Allan D Struthers, Petra Rauchhaus, Andrew D Morris, J Graeme Houston
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99190 (2014)
Common carotid intima media thickness (CIMT) and ankle brachial pressure index (ABPI) are used as surrogate marker of atherosclerosis, and have been shown to correlate with arterial stiffness, however their correlation with global atherosclerotic bur
Externí odkaz:
https://doaj.org/article/7d61aa1063714777972bf91a175cdab5