Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Stephen I. Lentz"'
Autor:
Sarah E. Elzinga, Emily J. Koubek, John M. Hayes, A. Carter, Faye E. Mendelson, Ian Webber-Davis, Stephen I. Lentz, Eva L. Feldman
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionThe prevalence of obesity, prediabetes, and diabetes continues to grow worldwide. These metabolic dysfunctions predispose individuals to neurodegenerative diseases and cognitive impairment, including dementias such as Alzheimer’s diseas
Externí odkaz:
https://doaj.org/article/1fd9916d6ee84d1785c25eb27f1044cc
Autor:
Sarah E. Elzinga, Rosemary Henn, Benjamin J. Murdock, Bhumsoo Kim, John M. Hayes, Faye Mendelson, Ian Webber-Davis, Sam Teener, Crystal Pacut, Stephen I. Lentz, Eva L. Feldman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Obesity, prediabetes, and diabetes are growing in prevalence worldwide. These metabolic disorders are associated with neurodegenerative diseases, particularly Alzheimer’s disease and Alzheimer’s disease related dementias. Innate inflammatory sign
Externí odkaz:
https://doaj.org/article/9488b3682a0c4c8ea380c898b36a645c
Publikováno v:
Biosensors, Vol 13, Iss 3, p 382 (2023)
The free calcium (Ca2+) levels in pancreatic beta cell organelles have been the subject of many recent investigations. Under pathophysiological conditions, disturbances in these pools have been linked to altered intracellular communication and cellul
Externí odkaz:
https://doaj.org/article/477d56f6a916454bb4fbd6fb95366929
Autor:
Juliana Bragazzi Cunha, Jared S. Elenbaas, Dhiman Maitra, Ning Kuo, Rodrigo Azuero-Dajud, Allison C. Ferguson, Megan S. Griffin, Stephen I. Lentz, Jordan A. Shavit, M. Bishr Omary
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Congenital erythropoietic porphyria (CEP) is a rare genetic disorder leading to accumulation of uro/coproporphyrin-I in tissues due to inhibition of uroporphyrinogen-III synthase. Clinical manifestations of CEP include bone fragility, severe
Externí odkaz:
https://doaj.org/article/e06a443978e94eb7b7e1577a00409af2
Autor:
Jennifer Kollmer, Ute Hegenbart, Christoph Kimmich, Ernst Hund, Jan C. Purrucker, John M. Hayes, Stephen I. Lentz, Georges Sam, Johann M. E. Jende, Stefan O. Schönland, Martin Bendszus, Sabine Heiland, Markus Weiler
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 5, Pp 799-807 (2020)
Abstract Objective To quantify peripheral nerve lesions in symptomatic and asymptomatic hereditary transthyretin amyloidosis with polyneuropathy (ATTRv‐PNP) by analyzing the magnetization transfer ratio (MTR) of the sciatic nerve, and to test its p
Externí odkaz:
https://doaj.org/article/9e22a57b5bc84ab196b434c089e25a39
Autor:
Amy E. Rumora, Giovanni LoGrasso, Julia A. Haidar, Justin J. Dolkowski, Stephen I. Lentz, Eva L. Feldman
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 1, Pp 58-70 (2019)
Dyslipidemia associated with T2D leads to diabetic neuropathy, a complication characterized by sensory neuronal dysfunction and peripheral nerve damage. Sensory dorsal root ganglion (DRG) neurons are dependent on axonal mitochondrial energy productio
Externí odkaz:
https://doaj.org/article/331716c6c3ab44e6a916cf6594627d9d
Autor:
Erwin R. Arias‐Hervert, Nicole Xu, Meredith Njus, Geoff G. Murphy, Yanan Hou, John A. Williams, Stephen I. Lentz, Stephen A. Ernst, Edward L. Stuenkel
Publikováno v:
Physiological Reports, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Members of the Rab3 gene family are considered central to membrane trafficking of synaptic vesicles at mammalian central excitatory synapses. Recent evidence, however, indicates that the Rab27B‐GTPase, which is highly homologous to the Rab
Externí odkaz:
https://doaj.org/article/a7337df874db458c983324c141ce0c03
Autor:
Kelli A. Sullivan, John M. Hayes, Timothy D. Wiggin, Carey Backus, Sang Su Oh, Stephen I. Lentz, Frank Brosius, III, Eva L. Feldman
Publikováno v:
Neurobiology of Disease, Vol 28, Iss 3, Pp 276-285 (2007)
Diabetic neuropathy (DN) is a debilitating complication of type 1 and type 2 diabetes. Rodent models of DN do not fully replicate the pathology observed in human patients. We examined DN in streptozotocin (STZ)-induced [B6] and spontaneous type 1 dia
Externí odkaz:
https://doaj.org/article/e226b4e0acac404d9de97b13a82cc4b6
The following supporting information can be downloaded at: https://zenodo.org/record/7735311#.ZBExInZBxEY, Movie S1: Image series of DS-1-transduced INS1-832/13 cells treated by agents known to modulate the ER and mitochondria Ca2+. Green represents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16aa633b9b303a3111f3b86944ce4398
Autor:
Sabine Heiland, Johann M E Jende, Martin Bendszus, Ernst Hund, John M. Hayes, Markus Weiler, Christoph Kimmich, Georges Sam, Jan C. Purrucker, Jennifer Kollmer, Stephen I. Lentz, Ute Hegenbart, Stefan Schönland
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 5, Pp 799-807 (2020)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Objective To quantify peripheral nerve lesions in symptomatic and asymptomatic hereditary transthyretin amyloidosis with polyneuropathy (ATTRv‐PNP) by analyzing the magnetization transfer ratio (MTR) of the sciatic nerve, and to test its potential