Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Stephen I Alexander"'
Autor:
Chloe Sligar, Ellie Reilly, Peter Cuthbertson, Kara L Vine, Katrina M Bird, Amal Elhage, Stephen I Alexander, Ronald Sluyter, Debbie Watson
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Objectives Donor haematopoietic stem cell transplantation treats leukaemia by inducing graft‐versus‐leukaemia (GVL) immunity. However, this benefit is often mitigated by graft‐versus‐host disease (GVHD), which is reduced by post‐tr
Externí odkaz:
https://doaj.org/article/ff78bb68913b4966b944916c5799b624
Autor:
Deepti Pilli, Alicia Zou, Ruebena Dawes, Joseph A Lopez, Fiona Tea, Ganesha Liyanage, Fiona XZ Lee, Vera Merheb, Samuel D Houston, Aleha Pillay, Hannah F Jones, Sudarshini Ramanathan, Shekeeb Mohammad, Anthony D Kelleher, Stephen I Alexander, Russell C Dale, Fabienne Brilot
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Abstract Objectives A dysregulated inflammatory response against the dopamine‐2 receptor (D2R) has been implicated in movement and psychiatric disorders. D2R antibodies were previously reported in a subset of these patients; however, the role of T
Externí odkaz:
https://doaj.org/article/3c1620496ec24e049604b01b5889ece8
Autor:
Jimmy Jianheng Zhou, Yuan Min Wang, Vincent W S Lee, Geoff Yu Zhang, Heather Medbury, Helen Williams, Ya Wang, Thian Kui Tan, David C H Harris, Stephen I Alexander, Anne M Durkan
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195657 (2018)
Studies disrupting the chemokine pathway CX3CL1 (fractalkine)/ CX3CR1 have shown decreased atherosclerosis in animal models but the techniques used to interrupt the pathway have not been easily translatable into human trials. DNA vaccination potentia
Externí odkaz:
https://doaj.org/article/d7906966913146b28c7ecaf6b0ff111c
Autor:
Anita van Zwieten, Elizabeth G. Ryan, Patrina Caldwell, Kirsten Howard, Allison Tong, Jonathan C. Craig, Stephen I. Alexander, Martin Howell, Armando Teixeira-Pinto, Carmel M. Hawley, Shilpanjali Jesudason, Amanda Walker, Fiona Mackie, Sean E. Kennedy, Steven McTaggart, Hugh J. McCarthy, Simon A. Carter, Siah Kim, Reginald Woodleigh, Anna Francis, Alistair R. Mallard, Amélie Bernier-Jean, David W. Johnson, Deirdre Hahn, Donna Reidlinger, Elaine Pascoe, Julie Varghese, Charani Kiriwandeniya, Liza Vergara, Nicholas Larkins, Luke Macauley, Michelle Irving, Rabia Khalid, Chandana Guha, Germaine Wong
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-4 (2022)
Abstract Background This update summarises key changes made to the protocol since the publication of the original protocol for the NAVKIDS2 trial of patient navigators for children with chronic kidney disease (CKD) experiencing social disadvantage an
Externí odkaz:
https://doaj.org/article/e9aefbd2b33b4ee98efbd4bb646dec48
Autor:
Edmund Y. M. Chung, MD, Katrina Blazek, BMedSci, Armando Teixeira-Pinto, PhD, Ankit Sharma, PhD, Siah Kim, PhD, Yingxin Lin, PhD, Karen Keung, PhD, Bhadran Bose, MBBS, Lukas Kairaitis, PhD, Hugh McCarthy, PhD, Pierre Ronco, PhD, Stephen I. Alexander, MD, Germaine Wong, PhD
Publikováno v:
Transplantation Direct, Vol 8, Iss 9, p e1357 (2022)
Background. Recurrent membranous nephropathy (MN) posttransplantation affects 35% to 50% of kidney transplant recipients (KTRs) and accounts for 50% allograft loss 5 y after diagnosis. Predictive factors for recurrent MN may include HLA-D risk allele
Externí odkaz:
https://doaj.org/article/be8d4697ae2c4af78ad7b0e22122bbcc
Autor:
Edmund Y. M. Chung, Katie Trinh, Jennifer Li, Sebastian Hayden Hahn, Zoltan H. Endre, Natasha M. Rogers, Stephen I. Alexander
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Heart and kidney failure often co-exist and confer high morbidity and mortality. The complex bi-directional nature of heart and kidney dysfunction is referred to as cardiorenal syndrome, and can be induced by acute or chronic dysfunction of either or
Externí odkaz:
https://doaj.org/article/43499c857416413bb4cd0ac53dfb06a9
Autor:
Chandana Guha, Rabia Khalid, Anita van Zwieten, Anna Francis, Carmel M. Hawley, Allison Jauré, Armando Teixeira-Pinto, Alistair R. Mallard, Amelie Bernier-Jean, David W. Johnson, Deirdre Hahn, Donna Reidlinger, Elaine M. Pascoe, Elizabeth G. Ryan, Fiona Mackie, Hugh J. McCarthy, Jonathan C. Craig, Julie Varghese, Charani Kiriwandeniya, Kirsten Howard, Nicholas G. Larkins, Luke Macauley, Amanda Walker, Martin Howell, Michelle Irving, Patrina H. Y. Caldwell, Reginald Woodleigh, Shilpanjali Jesudason, Simon A. Carter, Sean E. Kennedy, Stephen I. Alexander, Steven McTaggart, Germaine Wong
Publikováno v:
Pediatric Nephrology. 38:1577-1590
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6519b9291b2c3f3d9d44a681a88eeeb1
https://doi.org/10.1007/s00467-022-05772-2
https://doi.org/10.1007/s00467-022-05772-2
Publikováno v:
Pediatric Kidney Disease ISBN: 9783031116643
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c2cb6b1764d968b43f9cbf5355a27a
https://doi.org/10.1007/978-3-031-11665-0_13
https://doi.org/10.1007/978-3-031-11665-0_13
Membranous nephropathy: Clearer pathology and mechanisms identify potential strategies for treatment
Autor:
Edmund Y. M. Chung, Yuan M. Wang, Karen Keung, Min Hu, Hugh McCarthy, Germaine Wong, Lukas Kairaitis, Bhadran Bose, David C. H. Harris, Stephen I. Alexander
Publikováno v:
Frontiers in immunology. 13
Primary membranous nephropathy (PMN) is one of the common causes of adult-onset nephrotic syndrome and is characterized by autoantibodies against podocyte antigens causingin situimmune complex deposition. Much of our understanding of the disease mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b6d46109de1a4443ea79bebee314e8
https://pubmed.ncbi.nlm.nih.gov/36405681
https://pubmed.ncbi.nlm.nih.gov/36405681
Autor:
Katrina M. Bird, Sam R. Adhikary, Leigh Nicholson, Ronald Sluyter, Peter Cuthbertson, Chloe Sligar, Philip J. O'Connell, Stephen I. Alexander, Min Hu, Debbie Watson
Publikováno v:
Immunology
Graft‐versus‐host disease (GVHD) is a major complication of allogeneic haematopoietic stem cell transplantation (allo‐HSCT) that develops when donor T cells in the graft become reactive against the host. Post‐transplant cyclophosphamide (PTCy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74b8e74538fe7e6ab91745857646a63
https://doi.org/10.1111/imm.13374
https://doi.org/10.1111/imm.13374