Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Stephen I Alexander"'
Autor:
Chloe Sligar, Ellie Reilly, Peter Cuthbertson, Kara L Vine, Katrina M Bird, Amal Elhage, Stephen I Alexander, Ronald Sluyter, Debbie Watson
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Objectives Donor haematopoietic stem cell transplantation treats leukaemia by inducing graft‐versus‐leukaemia (GVL) immunity. However, this benefit is often mitigated by graft‐versus‐host disease (GVHD), which is reduced by post‐tr
Externí odkaz:
https://doaj.org/article/ff78bb68913b4966b944916c5799b624
Autor:
Deepti Pilli, Alicia Zou, Ruebena Dawes, Joseph A Lopez, Fiona Tea, Ganesha Liyanage, Fiona XZ Lee, Vera Merheb, Samuel D Houston, Aleha Pillay, Hannah F Jones, Sudarshini Ramanathan, Shekeeb Mohammad, Anthony D Kelleher, Stephen I Alexander, Russell C Dale, Fabienne Brilot
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Abstract Objectives A dysregulated inflammatory response against the dopamine‐2 receptor (D2R) has been implicated in movement and psychiatric disorders. D2R antibodies were previously reported in a subset of these patients; however, the role of T
Externí odkaz:
https://doaj.org/article/3c1620496ec24e049604b01b5889ece8
Autor:
Jimmy Jianheng Zhou, Yuan Min Wang, Vincent W S Lee, Geoff Yu Zhang, Heather Medbury, Helen Williams, Ya Wang, Thian Kui Tan, David C H Harris, Stephen I Alexander, Anne M Durkan
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195657 (2018)
Studies disrupting the chemokine pathway CX3CL1 (fractalkine)/ CX3CR1 have shown decreased atherosclerosis in animal models but the techniques used to interrupt the pathway have not been easily translatable into human trials. DNA vaccination potentia
Externí odkaz:
https://doaj.org/article/d7906966913146b28c7ecaf6b0ff111c
Autor:
Hope A. Tanudisastro, Katherine Holman, Gladys Ho, Elizabeth Farnsworth, Katrina Fisk, Thet Gayagay, Emma Hackett, Gemma Jenkins, Rahul Krishnaraj, Tiffany Lai, Karen Wong, Chirag Patel, Amali Mallawaarachchi, Andrew J. Mallett, Bruce Bennetts, Stephen I. Alexander, Hugh J. McCarthy
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Genetic testing in nephrology clinical practice has moved rapidly from a rare specialized test to routine practice both in pediatric and adult nephrology. However, clear information pertaining to the likely outcome of testing is still missin
Externí odkaz:
https://doaj.org/article/a7423469dafd4c0d913a4f96c90d30b8
Autor:
Simon H. Jiang, Vicki Athanasopoulos, Julia I. Ellyard, Aaron Chuah, Jean Cappello, Amelia Cook, Savit B. Prabhu, Jacob Cardenas, Jinghua Gu, Maurice Stanley, Jonathan A. Roco, Ilenia Papa, Mehmet Yabas, Giles D. Walters, Gaetan Burgio, Kathryn McKeon, James M. Byers, Charlotte Burrin, Anselm Enders, Lisa A. Miosge, Pablo F. Canete, Marija Jelusic, Velibor Tasic, Adrian C. Lungu, Stephen I. Alexander, Arthur R. Kitching, David A. Fulcher, Nan Shen, Todor Arsov, Paul A. Gatenby, Jeff J. Babon, Dominic F. Mallon, Carmen de Lucas Collantes, Eric A. Stone, Philip Wu, Matthew A. Field, Thomas D. Andrews, Eun Cho, Virginia Pascual, Matthew C. Cook, Carola G. Vinuesa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Function-altering variants of immune-related genes cause rare autoimmune syndromes, whereas their contribution to common autoimmune diseases remains uncharacterized. Here the authors show that rare variants of lupus-associated genes are present in th
Externí odkaz:
https://doaj.org/article/78a180011b6f49c096a0159adcd221f4
Autor:
Chandana Guha, Rabia Khalid, Anita van Zwieten, Anna Francis, Carmel M. Hawley, Allison Jauré, Armando Teixeira-Pinto, Alistair R. Mallard, Amelie Bernier-Jean, David W. Johnson, Deirdre Hahn, Donna Reidlinger, Elaine M. Pascoe, Elizabeth G. Ryan, Fiona Mackie, Hugh J. McCarthy, Jonathan C. Craig, Julie Varghese, Charani Kiriwandeniya, Kirsten Howard, Nicholas G. Larkins, Luke Macauley, Amanda Walker, Martin Howell, Michelle Irving, Patrina H. Y. Caldwell, Reginald Woodleigh, Shilpanjali Jesudason, Simon A. Carter, Sean E. Kennedy, Stephen I. Alexander, Steven McTaggart, Germaine Wong
Publikováno v:
Pediatric Nephrology. 38:1577-1590
Autor:
Samantha L. Ginn, Claus V. Hallwirth, Sophia H.Y. Liao, Erdahl T. Teber, Jonathan W. Arthur, Jianmin Wu, Hong Ching Lee, Szun S. Tay, Min Hu, Roger R. Reddel, Matthew P. McCormack, Adrian J. Thrasher, Marina Cavazzana, Stephen I. Alexander, Ian E. Alexander
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 6, Iss , Pp 1-14 (2017)
In early gene therapy trials for SCID-X1, using γ-retroviral vectors, T cell leukemias developed in a subset of patients secondary to insertional proto-oncogene activation. In contrast, we have reported development of T cell leukemias in SCID-X1 mic
Externí odkaz:
https://doaj.org/article/b02280667afa4fc3ad72ef3d4c6c6486
Autor:
Sarah L. White, PhD, William Rawlinson, FRACP, FRCPA, PhD, Peter Boan, FRACP, FRCPA, Vicky Sheppeard, FAFPHM, Germaine Wong, FRACP, PhD, Karen Waller, MBBS, Helen Opdam, FRACP, FCICM, John Kaldor, PhD, Michael Fink, MD, FRACS, Deborah Verran, MD, FRACS, Angela Webster, PhD, FRCP, FRACP, Kate Wyburn, FRACP, PhD, Lindsay Grayson, MD, FRACP, FAFPHM, FRCP, FIDSA, Allan Glanville, MD, FRACP, Nick Cross, MD, PhD, Ashley Irish, FRACP, Toby Coates, FRACP, PhD, Anthony Griffin, FRACS, Greg Snell, MD, FRACP, Stephen I. Alexander, MD, FRACP, Scott Campbell, FRACP, PhD, Steven Chadban, FRACP, PhD, Peter Macdonald, MD, FRACP, PhD, Paul Manley, FRACP, Eva Mehakovic, Vidya Ramachandran, MBBS, Alicia Mitchell, PhD, Michael Ison, MD
Publikováno v:
Transplantation Direct, Vol 5, Iss 1, p e416 (2019)
Abstract. In 2016, the Transplantation Society of Australia and New Zealand, with the support of the Australian Government Organ and Tissue authority, commissioned a literature review on the topic of infectious disease transmission from deceased dono
Externí odkaz:
https://doaj.org/article/ef8c065faade40b78960ef114e635c90
Autor:
Heon Yung Gee, Carolin E. Sadowski, Pardeep K. Aggarwal, Jonathan D. Porath, Toma A. Yakulov, Markus Schueler, Svjetlana Lovric, Shazia Ashraf, Daniela A. Braun, Jan Halbritter, Humphrey Fang, Rannar Airik, Virginia Vega-Warner, Kyeong Jee Cho, Timothy A. Chan, Luc G. T. Morris, Charles ffrench-Constant, Nicholas Allen, Helen McNeill, Rainer Büscher, Henriette Kyrieleis, Michael Wallot, Ariana Gaspert, Thomas Kistler, David V. Milford, Moin A. Saleem, Wee Teik Keng, Stephen I. Alexander, Rudolph P. Valentini, Christoph Licht, Jun C. Teh, Radovan Bogdanovic, Ania Koziell, Agnieszka Bierzynska, Neveen A. Soliman, Edgar A. Otto, Richard P. Lifton, Lawrence B. Holzman, Nicholas E. S. Sibinga, Gerd Walz, Alda Tufro, Friedhelm Hildebrandt
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Steroid-sensitive nephrotic syndrome (SRNS) can cause CKD and necessitate kidney transplant. Here the authors identify FAT1 mutations by homozygosity mapping and whole-exome sequencing in families with SRNS and provide functional mouse and zebrafish
Externí odkaz:
https://doaj.org/article/28d36207928640028a9a892d5c32fd4f
Publikováno v:
Pediatric Kidney Disease ISBN: 9783031116643
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c2cb6b1764d968b43f9cbf5355a27a
https://doi.org/10.1007/978-3-031-11665-0_13
https://doi.org/10.1007/978-3-031-11665-0_13