Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephen H. Reaney"'
Autor:
Amy B. Manning-Boğ, W. Michael Caudle, Xiomara A. Perez, Stephen H. Reaney, Ronald Paletzki, Martha Z. Isla, Vivian P. Chou, Alison L. McCormack, Gary W. Miller, J. William Langston, Charles R. Gerfen, Donato A. DiMonte
Publikováno v:
Neurobiology of Disease, Vol 27, Iss 2, Pp 141-150 (2007)
Mutations in the gene for DJ-1 have been associated with early-onset autosomal recessive parkinsonism. Previous studies of null DJ-1 mice have shown alterations in striatal dopamine (DA) transmission with no DAergic cell loss. Here we characterize a
Externí odkaz:
https://doaj.org/article/361092cdf0f14aeea0d1a41938d92889
Autor:
Wenbo Zhou, Vladimir N. Uversky, Donato A. Di Monte, Anthony L. Fink, Chunmei Long, Stephen H. Reaney
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2010, 1802 (3), pp.322. ⟨10.1016/j.bbadis.2009.12.004⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2010, 1802 (3), pp.322. ⟨10.1016/j.bbadis.2009.12.004⟩
Oxidative stress and aggregation of the presynaptic protein alpha-synuclein (alpha-Syn) are implied in the pathogenesis of Parkinson's disease and several other neurodegenerative diseases. Various posttranslational modifications, such as oxidation, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a14bab764927702d7adf7251bc3d844
Autor:
Stephen H. Reaney, W. Michael Caudle, Martha Z. Isla, J. William Langston, Charles R. Gerfen, Vivian P. Chou, Donato DiMonte, Xiomara A. Perez, Ronald F. Paletzki, Amy B. Manning-Boğ, Alison L. McCormack, Gary W. Miller
Publikováno v:
Neurobiology of Disease, Vol 27, Iss 2, Pp 141-150 (2007)
Mutations in the gene for DJ-1 have been associated with early-onset autosomal recessive parkinsonism. Previous studies of null DJ-1 mice have shown alterations in striatal dopamine (DA) transmission with no DAergic cell loss. Here we characterize a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14006183dddac6ec51f8cc9d34bd801f
https://doi.org/10.1016/j.nbd.2007.03.014
https://doi.org/10.1016/j.nbd.2007.03.014
Publikováno v:
Toxicological Sciences. 93:114-124
Concern over the neurotoxic effects of chronic moderate exposures to manganese has arisen due to increased awareness of occupational exposures and to the use of methylcyclopentadienyl manganese tricarbonyl, a manganese-containing gasoline antiknock a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7996d87a2d7567d2601df662fe61d6df
https://doi.org/10.1093/toxsci/kfl028
https://doi.org/10.1093/toxsci/kfl028
Publikováno v:
Molecular Brain Research. 134:52-56
Mechanisms involved in paraquat neurotoxicity that selectively target nigrostriatal dopaminergic neurons remain relatively unknown. In this study, we tested the hypotheses that paraquat exposure leads to the production of reactive oxygen species (ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df805b0822a2ed8ff292961b453b7f4
https://doi.org/10.1016/j.molbrainres.2004.11.005
https://doi.org/10.1016/j.molbrainres.2004.11.005
Publikováno v:
Brain Research. 973:1-15
Manganese (Mn) may interfere with iron regulation by altering the binding of iron regulatory proteins (IRPs) to their response elements found on the mRNA encoding proteins critical to iron homeostasis. To explore this, the effects of 24-h in vitro ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c47e439c57b6ef0dec1ee01c1bfd802
https://doi.org/10.1016/s0006-8993(03)02457-0
https://doi.org/10.1016/s0006-8993(03)02457-0
Autor:
Abigail M. Batchelder, Robert A. Goldbeck, James W. Lewis, Stephen H. Reaney, David S. Kliger, Raymond M. Esquerra, Youxian Wen
Publikováno v:
Biophysical Journal. 78:3227-3239
The geminate ligand recombination reactions of photolyzed carbonmonoxyhemoglobin were studied in a nanosecond double-excitation-pulse time-resolved absorption experiment. The second laser pulse, delayed by intervals as long as 400 ns after the first,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca68cda2c5b4d52cdb7be609b9938095
https://doi.org/10.1016/s0006-3495(00)76859-7
https://doi.org/10.1016/s0006-3495(00)76859-7
Publikováno v:
The Journal of biological chemistry. 282(8)
Several observations have implicated oxidative stress and aggregation of the presynaptic protein alpha-synuclein in the pathogenesis of Parkinson disease. alpha-Synuclein has been shown to have affinity for unsaturated fatty acids and membranes enric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47813db6893cff901229bfc1122d2b09
https://pubmed.ncbi.nlm.nih.gov/17189262
https://pubmed.ncbi.nlm.nih.gov/17189262
Autor:
Amy B. Manning-Boğ, Donato A. Di Monte, Alison L. McCormack, Stephen H. Reaney, Vivian P. Chou, Jennifer A. Johnston, Louisa C. Johnston, J. William Langston
Publikováno v:
Annals of neurology. 60(2)
Systemic administration of ubiquitin-proteasome system inhibitors to rodents has been reported to induce certain behavioral and neuropathological features of Parkinson's disease. The goal of this study was to replicate these observations by administe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65261c6bdb0a09f4f757366a2b7cf4b
https://pubmed.ncbi.nlm.nih.gov/15236415
https://pubmed.ncbi.nlm.nih.gov/15236415
Publikováno v:
Experimental neurology. 202(2)
Impairment of the ubiquitin-proteasome system (UPS) has been implicated in the pathogenesis of Parkinson's disease (PD). Because the neurodegenerative process of PD results in a severe loss of dopaminergic cells, previous in vitro studies have invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96be8838ea010cd67dc4d95cd5899a0
https://pubmed.ncbi.nlm.nih.gov/16920101
https://pubmed.ncbi.nlm.nih.gov/16920101