Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stephen H. Lai"'
Autor:
Carol L. Vinton, Carly E. Starke, Alexandra M. Ortiz, Stephen H. Lai, Jacob K. Flynn, Ornella Sortino, Kenneth Knox, Irini Sereti, Jason Brenchley
Publikováno v:
Pathogens and Immunity, Vol 5, Iss 1, Pp 68-88 (2020)
Abstract Background: Microbial translocation occurs after damage to the structural and/or immunological barrier of the gastrointestinal (GI) tract into circulation. Microbial components that translocate from the lumen of the GI tract directly stimula
Externí odkaz:
https://doaj.org/article/d13267769b144025882a00af089fc6cc
Autor:
Irini Sereti, Kenneth S. Knox, Jacob K. Flynn, Jason M. Brenchley, Stephen H. Lai, Alexandra M. Ortiz, Ornella Sortino, Carol L. Vinton, Carly E. Starke
Publikováno v:
Pathogens and Immunity, Vol 5, Iss 1, Pp 68-88 (2020)
Pathogens and Immunity
Pathogens and Immunity
Background: Microbial translocation occurs after damage to the structural and/or immunological barrier of the gastrointestinal (GI) tract into circulation. Microbial components that translocate from the lumen of the GI tract directly stimulate the im
Autor:
Xiuning Le, Minghao Dang, Venkatesh L. Hegde, Bo Jiang, Ravaen Slay, Weihong Xiao, Keiko Akagi, Joseph Fresquez, Kathrina L. Marcelo, Qianyun Luo, Pragya Sinha, Ananta V. Yanamandra, Joe Dan Dunn, Diana Bell, Michelle Williams, Edwin Parra, Ryan Goepfert, Stephen H. Lai, Neil Gross, Amit Agrawal, Alexandre Reuben, Jeffrey Myers, Michael A. Curran, K. Jagannadha Sastry, Linghua Wang, Maura L. Gillison
The authors have withdrawn their manuscript because a major revision is in progress to incorporate additional data. Therefore, the authors do not wish this work to be cited as reference for the project. If you have any questions, please contact the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef65d3876e88b562fd9139ddc404a426
https://doi.org/10.1101/2021.12.02.21266776
https://doi.org/10.1101/2021.12.02.21266776
Autor:
Joseph C. Mudd, R. Keith Reeves, Virginia Sheik, Brian Richardson, David Palesch, Andrea Lisco, Mirko Paiardini, Kathleen Busman-Sahay, Jacob D. Estes, Irini Sereti, Jason M. Brenchley, Stephen H. Lai, Sarah R. DiNapoli, Claire Deleage, Mark J. Cameron
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Innate lymphoid cells (ILCs) play critical roles in mucosal barrier defense and tissue homeostasis. While ILCs are depleted in HIV-1 infection, this phenomenon is not a generalized feature of all viral infections. Here we show in untreated SIV-infect
Autor:
Sarah R. DiNapoli, Carly E. Starke, Jacob D. Estes, Jason M. Brenchley, Alexandra M. Ortiz, Ornella Sortino, Stephen H. Lai, Carol L. Vinton, Kathleen Busman-Sahay, Leslie Johnston, Yasmine Belkaid, Jacob K. Flynn, Ivan Vujkovic-Cvijin, Joseph C. Mudd, MacKenzie K.E. Long
Publikováno v:
Nature medicine
Intestinal microbial dysbiosis has been described in individuals with an HIV-1 infection and may underlie persistent inflammation in chronic infection, thereby contributing to disease progression. Herein, we induced an HIV-1-like intestinal dysbiosis
Simian Immunodeficiency Virus Infects Functionally Polarized Memory CD4 T Cells Equivalently In Vivo
Autor:
Jason M. Brenchley, Carol L. Vinton, Jacob K. Flynn, Stephen H. Lai, Alexandra M. Ortiz, Joseph C. Mudd, Carly E. Starke
Among the numerous immunological abnormalities observed in chronically human immunodeficiency virus (HIV)-infected individuals, perturbations in memory CD4 T cells are thought to contribute specifically to disease pathogenesis. Among these, functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d62916fa5ff84afd2e149aeb6ebc6ea
https://europepmc.org/articles/PMC6475783/
https://europepmc.org/articles/PMC6475783/
Autor:
Joseph C. Mudd, Samuel Darko, James E. McLaren, Carly E. Starke, Fan Wu, Kristin Ladell, Vanessa M. Hirsch, Alexandra M. Ortiz, David Price, Jacob K. Flynn, Jason M. Brenchley, Stephen H. Lai, Daniel C. Douek, Carol L. Vinton
Publikováno v:
J Clin Invest
CD8(+) T cell responses are necessary for immune control of simian immunodeficiency virus (SIV). However, the key parameters that dictate antiviral potency remain elusive, conceivably because most studies to date have been restricted to analyses of c